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Azilect generically known as rasagiline is a prescription medication used to treat symptoms of Parkinson's disease. It is classified as a MAO-B inhibitor. It works by increasing certain brain chemicals that help control movement. It works by slowing down the breakdown of dopamine in the brain, which is a chemical that regulates movement in the body.
Rasagiline is available in tablet form and is typically taken once a day with or without food. It can be used alone or in combination with other medications to improve mobility, reduce tremors, and stabilize mood. It helps improve stiffness, shakiness, and difficulty moving. It can be taken with or without a dopamine agonist and may also help reduce the amount of "off" time, which is the period of slow movement or stiffness experienced by patients.
Uses and Dosage
Azilect (Rasagiline) is usually prescribed to be taken once or twice a day, orally by mouth with or without food as directed by the doctor. If the medication is taken once, it is usually recommended to be taken at bedtime. To ensure maximum benefits, take Nizatidine regularly, preferably at the same time every day.
Do not increase the dosage or take the medication more frequently or for longer than prescribed, as doing so may increase the risk of side effects and will not improve the condition any faster. Continue taking the medication for the entire duration of the prescribed treatment, even if symptoms improve. Always consult with a healthcare provider for personalized recommendations on dosing, frequency, and duration of treatment, as they may vary depending on the individual's medical condition and needs.
- For monotherapy for Parkinson's disease, the typical dose is 1 mg per day taken orally.
- For adjunct therapy, the typical dose is also 1 mg per day, either alone or with a levodopa medication.
- In cases where Azilect is used as adjunct therapy with levodopa, the starting dose is usually 0.5 mg per day, which may be gradually increased up to 1 mg per day.
Common Side Effects of Azilect (Rasagiline):
- Dry mouth
- Joint pain
- Loss of appetite
- Stomach upset
- Weight loss
Serious Side Effects of Azilect (Rasagiline):
- Easy bruising and bleeding
- Hypertensive crisis (severe headache, irregular heartbeat, chest pain, neck stiffness, severe vomiting, widened pupils, increased sensitivity to light)
- Loss of balance
- Mental or mood changes
- Swollen ankles
- Symptoms of serotonin syndrome (fast heartbeat, hallucinations, agitation, loss of coordination, severe dizziness, unexplained fever)
- Unusual strong urges
- Worsening muscle stiffness
Form and Strength
Azilect (Rasagiline) is available in the following forms and strength:
- 0.5 mg
- 1 mg
- 0.5 mg
- 1 mg
- Interactions with other medications: Rasagiline can interact with other medications, including some antidepressants and opioids. Certain foods and beverages, such as aged cheese and wine, also contain substances that can interact with Azilect.
- Rasagiline may cause low blood pressure (hypotension), especially in elderly patients. Patients should be monitored for signs of hypotension, such as dizziness and light-headedness.
- There have been rare reports of impulse control disorders, such as pathological gambling and hypersexuality, in patients taking Azilect.
- There have been reports of an increased risk of melanoma in patients taking Azilect.
- Azilect may cause or exacerbate sleep disorders, such as insomnia and vivid dreams.
- Rasagiline may increase the risk of cardiovascular events, such as stroke and heart attack, in patients with preexisting cardiovascular disease.
- Azilect should be used with caution in patients with liver impairment, as it may increase the risk of liver damage.
- Azilect should be used with caution in patients with severe renal impairment, as it may increase the risk of adverse effects.
- Patients taking Rasagiline should inform their healthcare providers before undergoing any surgical procedures, as Azilect may interact with certain anesthetics and pain medications.
- Azilect should not be used during pregnancy or breastfeeding, as there is a lack of available data on its safety and efficacy in these populations.
Frequently Asked Questions (FAQ)
Can Azilect be crushed or split?
Do not crush or split Azilect tablets without consulting a pharmacist first.
What should I do if I miss a dose of Azilect?
If you miss a dose of Azilect, take it as soon as you remember. However, if it is close to the time of your next dose, skip the missed dose and continue with your regular dosing schedule.
Can I adjust the dose of Azilect on my own?
No, follow the dosing instructions provided by your healthcare provider. Do not adjust the dose of Azilect without consulting with them first.
Are there any foods or medications to avoid while taking Azilect?
Yes, there are certain foods and medications that should be avoided while taking Azilect. Consult with your healthcare provider for a complete list.
How long does it take rasagiline (Azilect) to work?
Rasagiline (Azilect) can start to improve your PD symptoms within 1 week of starting the medication.
It's important to purchase Azilect from verified Canadian pharmacy.