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Zonegran, containing the active ingredient zonisamide, is a prescription oral medication prescribed in conjunction with other drugs to treat partial seizures in adults and teenagers ages 16 or older with epilepsy. Zonisamide works by reducing brain activity and blocking sodium channels, helping to prevent seizure activity.
Zonegran can be used alone or in combination with other medications to control seizures. It helps to prevent and control episodes of seizures by binding to sodium and voltage-sensitive calcium channels, resulting in decreased neuronal depolarization and hyper synchronization. Capsule forms of Zonegran are available in 100 mg, 50 mg, and 25 mg dosages.
Uses and Dosage
Zonegran should be taken exactly as prescribed by a healthcare provider. It can be taken with or without food, but should be swallowed whole and not chewed, crushed, or broken. Patients should not stop taking Zonegran or adjust the dosage without first consulting with their doctor.
To ensure the effectiveness of Zonegran, it should be taken regularly and maintained at a stable level in the body. A dosing schedule should be created and followed to prevent missed doses. Always follow your doctor's instructions and avoid altering your Zonegran dosage or abruptly stopping the medication, as doing so could result in worsening your condition.
The recommended dosage of Zonegran can vary based on a variety of factors, including age, weight, and medical history. However, the initial dose of Zonegran is typically 100 mg per day, with the option to increase to 200 mg per day after two weeks. The dosage may be further increased to 300 or 400 mg per day to achieve the desired therapeutic effect but should not exceed 600 mg/day. Consult with a healthcare professional before starting or adjusting the dosage of Zonegran.
Common Side Effects of Zonegran (Zonisamide):
- Blurred vision
- Double vision
- Insomnia or trouble sleeping
- Lack of coordination
- Loss of appetite
Serious Side Effects of Zonegran (Zonisamide):
- Change in urine output
- Decreased sweating
- Depression or suicidal thoughts
- Eye pain
- Mental or mood problems
- Painful urination
- Speech problems
- Sudden abdominal pain
- Symptoms of metabolic acidosis (bone pain, irregular heartbeat, severe drowsiness)
Form and strength
Zonegran (Zonisamide) is available in the following forms and strength:
- 25 mg
- 50 mg
- 100 mg
- Do drink alcohol while taking Zonegran, as it may increase the risk of certain side effects such as drowsiness or dizziness.
- Caution is advised when starting or stopping Zonegran or changing the dose. Patients should inform their doctor of any other medications they are taking before starting treatment with Zonegran due to drug interactions.
- Zonisamide may cause drowsiness, dizziness, or difficulty with concentration, so patients should be cautious when driving or operating heavy machinery until they know how the medication affects them.
- Depression is a possible side effect of taking Zonisamide, and patients should consult with their doctors if they experience any mood changes or depressive symptoms while taking the medication.
- The safety of Zonegran during pregnancy is not well established, and women who are pregnant or planning to become pregnant should consult with their healthcare provider before taking the medication.
- Individuals taking Zonisamide may experience suicidal thoughts or behavior. This risk may be higher in individuals with a history of depression or other mental health conditions.
- Individuals may have an allergic reaction to Zonegran. Symptoms of an allergic reaction may include hives, difficulty breathing, or swelling of the face, lips, tongue, or throat.
- Zonegran may increase the risk of kidney stone formation in some individuals. This risk may be higher in individuals who have a history of kidney stones or who are taking other medications that may increase the risk of kidney stones.
Frequently Asked Questions (FAQ)
How does Zonegran work to prevent seizures?
It is not exactly clear how Zonegran works to prevent seizures, but it is believed to reduce the excessive and abnormal activity in the brain that leads to seizures.
Is Zonegran safe to use during pregnancy?
The safety of Zonegran during pregnancy is not well established, and women who are pregnant or planning to become pregnant should consult with their healthcare provider before taking the medication.
Is it safe to drink alcohol while taking Zonegran?
Do drink alcohol while taking Zonegran, as it may increase the risk of certain side effects such as drowsiness or dizziness.
How long does it take for Zonegran to start working?
The effects of Zonegran may take several weeks to become apparent, and the medication should be taken regularly to achieve maximum benefit.
It's important to purchase Zonegran from verified Canadian pharmacy.