Prolopa CR (Levodopa/Benserazide)

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Prolopa CR Brand
Dosage Quantity & Price
Levodopa/Benserazide (Generic alternate to Prolopa CR) Generic

We don't sell this generic-version medication.

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Table of contents:

Prolopa CR is an oral medication used in the treatment of Parkinson's disease. Prolopa CR is a controlled-release formulation of the medication, which means that it is designed to release the active ingredients slowly over time, providing more consistent symptom control throughout the day compared to immediate-release formulations.

Prolopa is a combination of two active ingredients, levodopa and benserazide. Levodopa is converted into dopamine in the brain, which helps to improve motor function in individuals with Parkinson's disease. Benserazide helps to increase the effectiveness of levodopa by preventing it from being broken down in the body before it can reach the brain.

Use and Dosage

Prolopa CR is available in capsule form and should be taken orally with or without food, one to three times per day. It should be taken exactly as prescribed by a doctor. It should not be crushed or split as it is designed to release the active ingredients slowly over time. Altering the medication can affect its release pattern and effectiveness.

The dosage and frequency of the medication may vary depending on the individual's specific symptoms. Take Prolopa CR at the same time each day to maintain a consistent level of medication in the body.

If you miss a dose of Prolopa CR, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not double up on doses to make up for a missed one.

Side Effects

Common Side Effects of Prolopa CR (Levodopa/Benserazide):

  • Agitation
  • Anxiety
  • Blurred vision
  • Confusion
  • Dizziness
  • Drowsiness
  • Dry mouth
  • Headache
  • Insomnia
  • Loss of appetite
  • Muscle cramps
  • Nausea
  • Skin rash
  • Sweating
  • Urinary retention
  • Vomiting

Serious Side Effects of Prolopa CR (Levodopa/Benserazide):

  • Hallucinations
  • Psychosis
  • Compulsive behaviors (such as gambling, shopping, and sex)
  • Orthostatic hypotension (drop in blood pressure upon standing)
  • Dyskinesia (involuntary movements)
  • Worsening of Parkinson's disease symptoms (when medication wears off)
  • Neuroleptic malignant syndrome (rare but potentially life-threatening reaction)

Forms and Strength

Prolopa CR (Levodopa/Benserazide) is available in the following forms and strength:

Prolopa CR: Controlled Release Capsule

  • 100/25mg


  • Interactions with other medications: Prolopa CR can interact with other medications, so inform your doctor of all medications you are taking, including over-the-counter medications and supplements.
  • Side effects: Prolopa CR can cause some side effects, such as nausea, vomiting, dizziness, and confusion, particularly at higher doses. It can also cause dyskinesias, which are involuntary movements, or fluctuations in response, which are unpredictable wearing-off of the effect.
  • Pre-existing conditions: Prolopa CR may not be recommended for individuals with certain pre-existing conditions, such as glaucoma, heart disease, or a history of gastric ulcers.
  • Pregnancy and breastfeeding: Prolopa CR is not recommended for use during pregnancy or breastfeeding as its safety during these times has not been established.
  • Abnormal movements: Prolopa CR may cause or worsen abnormal movements, such as tics or tremors, in some individuals.
  • Mental health: Prolopa CR may cause or worsen mental health conditions such as depression, anxiety, or hallucinations.
  • Kidney or liver function: Prolopa CR may not be recommended for individuals with impaired kidney or liver function, as it is metabolized in the liver and excreted by the kidneys.
  • Avoiding high-protein foods: Prolopa CR may not work as well if it is taken with high-protein foods or supplements, so avoid these foods or supplements within 1 hour before and after taking the medication.
  • Withdrawal symptoms: Prolopa CR should be gradually reduced under medical supervision to avoid withdrawal symptoms such as fever, muscle stiffness, or increased Parkinson's symptoms.
  • Driving and operating machinery: Prolopa CR may cause drowsiness or dizziness, so caution should be taken when driving or operating machinery.

Frequently Asked Questions (FAQ)

How long does it take for Prolopa CR to start working?

The time it takes for Prolopa CR to start working can vary depending on the individual and their specific symptoms. It may take several weeks for the full effect of the medication to be felt.

Does Prolopa CR need to be taken at specific times during the day?

Prolopa CR should be taken at specific times during the day as directed by a doctor. The timing of the doses may depend on the individual's specific symptoms and response to the medication.

Can Prolopa CR be taken by pregnant or breastfeeding women?

Prolopa CR is not recommended for use during pregnancy or breastfeeding as its safety during these times has not been established. Talk to a doctor before stopping or starting any medications during pregnancy or breastfeeding.

Does Prolopa CR cure Parkinson's disease?

Prolopa CR is not a cure for Parkinson's disease, but it can help to improve motor function and reduce symptoms associated with the disease. Treatment with Prolopa CR should be continued as directed by a doctor.


It's important to purchase Prolopa CR from verified Canadian pharmacy.

Additional information

Generic name:



Controlled Release Capsule



Quantities Available:



Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Prolopa CR (Levodopa/Benserazide). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Prolopa CR (Levodopa/Benserazide).