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Formulation: Tablet
Prescription Required
Formulation: Tablet
(Generic Alternative)
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Trilafon contains the active ingredient perphenazine. It is a prescription medication used to treat certain mental health conditions.
Trilafon is used to manage symptoms of schizophrenia and other psychotic disorders.
These conditions may cause symptoms such as:
Trilafon can help reduce these symptoms and improve thinking and behavior in some people.
Perphenazine has also been used for the short-term treatment of severe anxiety in certain situations.
Because it can cause significant side effects, it is generally not a first-choice treatment for routine anxiety and is used only when a healthcare provider decides it is appropriate.
Trilafon belongs to a group of medications called typical, or first-generation, antipsychotics.
It works mainly by blocking dopamine D2 receptors in the brain.
Dopamine is a chemical messenger involved in mood, thinking, movement, and behavior.
In some psychotic disorders, dopamine activity may be too high in certain parts of the brain.
By reducing dopamine signaling, Trilafon can help:
For schizophrenia, Trilafon may be used as a longer-term treatment if it continues to help and side effects remain manageable.
It does not cure schizophrenia, but it can help control symptoms.
Your healthcare provider will monitor your response to treatment and watch for side effects, especially movement-related side effects that can occur with typical antipsychotics.
Trilafon tablets are taken by mouth, usually 2 to 4 times daily, depending on the condition being treated and the dose prescribed by your healthcare provider.
Try to take each dose at about the same time every day.
Take Trilafon exactly as prescribed. Do not take more medication, take it more often, or change your dose unless your healthcare provider tells you to.
For adults with schizophrenia who are not hospitalized:
Starting dose: 4 to 8 mg three times daily.
Once symptoms are controlled, the dose should usually be reduced to the lowest effective dose.
For hospitalized adults with schizophrenia:
Usual dose: 8 to 16 mg taken 2 to 4 times daily.
Doses above 24 mg per day should generally be reserved for patients who are hospitalized or closely monitored because the risk of movement-related side effects increases as the dose rises.
Doses above 64 mg per day should be avoided.
Older adults may be more sensitive to perphenazine and may have higher medication levels in the body from the same dose.
A lower starting dose is generally recommended.
Your healthcare provider may increase the dose slowly and monitor you more closely for side effects such as dizziness, low blood pressure, drowsiness, or movement problems.
Continue taking Trilafon as prescribed even if you begin to feel better.
The medication may take time to provide its full benefit, and stopping treatment too soon may cause symptoms to return.
Do not change your treatment schedule without speaking with your healthcare provider.
Do not suddenly stop taking Trilafon unless your healthcare provider tells you to.
Stopping perphenazine abruptly after regular use may cause symptoms such as:
Your healthcare provider may gradually reduce your dose when treatment needs to be stopped.
If you miss a dose of Trilafon, take it when you remember unless it is almost time for your next scheduled dose.
If your next dose is approaching, skip the missed dose and continue with your regular schedule.
Do not take two doses at the same time to make up for a missed dose.
Your Trilafon dose is individualized based on your condition, symptoms, response to treatment, age, and side effects.
Because higher doses increase the risk of movement-related side effects, your healthcare provider will generally aim to use the lowest dose that effectively controls your symptoms.
Trilafon (perphenazine) is available in the following forms and strength:
Trilafon is not approved to treat dementia-related psychosis.
Older adults with dementia-related psychosis who take antipsychotic medications have an increased risk of death.
Long-term use of Trilafon can cause tardive dyskinesia, a movement disorder that may become permanent.
Symptoms may include:
The risk increases with longer treatment and higher total exposure, and it is higher in older adults.
Your healthcare provider will usually aim to use the lowest effective dose and reassess regularly whether treatment is still needed.
Rarely, Trilafon can cause neuroleptic malignant syndrome (NMS), a serious and potentially life-threatening reaction to antipsychotic medications.
Symptoms may include:
Seek emergency medical attention if these symptoms occur.
Perphenazine has been associated with leukopenia, neutropenia, and agranulocytosis, which are conditions involving dangerously low numbers of certain white blood cells.
The risk may be greater if you already have a low white blood cell count or have previously developed low blood counts from another medication.
Contact your healthcare provider if you develop fever, chills, sore throat, or other signs of infection. Your healthcare provider may order blood tests if you are at increased risk.
Trilafon can cause a sudden drop in blood pressure when you stand up, called orthostatic hypotension.
This may cause:
Drowsiness and problems with balance can also increase the risk of falls, especially in older adults.
Stand up slowly from a sitting or lying position.
Trilafon can cause drowsiness and may impair your thinking, coordination, or reaction time.
Avoid driving, operating machinery, or doing other activities that require full alertness until you know how the medication affects you.
Trilafon may lower the seizure threshold.
Tell your healthcare provider if you have epilepsy or a history of seizures before starting treatment.
Your healthcare provider may monitor you more closely if seizure risk is a concern.
Perphenazine and other phenothiazine antipsychotics can affect the heart’s electrical activity and have been associated with abnormal heart rhythms.
Tell your healthcare provider if you have:
Seek medical attention if you develop fainting, severe dizziness, or a fast or irregular heartbeat.
People with depression or other psychiatric conditions should be monitored for worsening mood or suicidal thoughts during treatment.
Tell your healthcare provider promptly if you develop new or worsening depression, thoughts of self-harm, or major changes in mood or behavior.
Seek immediate help if there is an immediate risk of self-harm.
Trilafon can interact with medications that affect the brain and nervous system.
These may include:
Alcohol can increase drowsiness, dizziness, and other nervous-system effects.
Tell your healthcare provider about all prescription medications, over-the-counter products, vitamins, supplements, and herbal products you use.
Do not take Trilafon if you have had a serious allergic reaction to perphenazine or another phenothiazine medication.
Seek immediate medical attention if you develop:
Tell your healthcare provider if you are pregnant or planning to become pregnant.
Perphenazine should be used during pregnancy only when the expected benefit outweighs the potential risk.
Babies exposed to antipsychotics during the third trimester may develop temporary movement problems or withdrawal symptoms after birth, including tremors, muscle stiffness or weakness, sleepiness, breathing problems, or feeding difficulties.
The safety of perphenazine during breastfeeding has not been fully established.
Tell your healthcare provider if you are breastfeeding or planning to breastfeed. Your healthcare provider will weigh the potential benefits of treatment against possible risks to the nursing infant.
During treatment, your healthcare provider may monitor you for:
Regular monitoring helps determine whether Trilafon remains safe and whether the dose should be adjusted.
Trilafon may begin to reduce symptoms such as agitation or severe anxiety within several days. Other symptoms, especially those related to schizophrenia or psychosis, may take several weeks to improve more fully. Continue taking Trilafon as prescribed even if you do not notice an immediate change.
Trilafon is not considered addictive and does not usually cause cravings or compulsive use. However, your body can become used to the medication over time. Stopping Trilafon suddenly may cause symptoms such as nausea, vomiting, dizziness, shakiness, or a return of the condition being treated. Do not stop taking Trilafon without speaking with your healthcare provider. Your dose may need to be reduced gradually.
Yes. Weight gain can occur while taking Trilafon, although it does not affect everyone. Changes in appetite, activity level, or metabolism may contribute. Your healthcare provider may monitor your weight during treatment, especially if you are taking Trilafon for a long period. Contact your healthcare provider if you notice rapid or significant weight gain.
| Generic name: | Perphenazine |
|---|---|
| Formulation: | Tablet |
| Strength(s): | 2mg, 4mg, 8mg, 16mg |
| Quantities Available: | 100 |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Trilafon (perphenazine) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.
Here’s what you need to know:
Dosage and Quantity: Trilafon is commonly prescribed in dosages of 2 mg, 4 mg, 8 mg or 16 mg, taken multiple times daily. For example, if prescribed 16 mg taken twice daily, then for a 90-day supply, you would order 180 tablets (90 days x 2 tablets per day).
Yes, we sell perphenazine on our website. You can enjoy low prices when you order through us. To purchase perphenazine, you will need a valid prescription from your healthcare provider. We require this prescription to dispense the medication safely and appropriately. You have the option to submit your prescription by mailing it to us, faxing it, or uploading it through your online account.
Yes, we ship Trilafon (perphenazine) to both the United States and Puerto Rico.
Watch how Online Pharmacies Canada is helping customers save money on their medications.
Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Trilafon (Perphenazine). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Trilafon (Perphenazine).
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