Stalevo 200 (Carbidopa/levodopa/entacapone) Shopper Approved

Prescription Prescription Required FormationFormulation: Tablet

Stalevo 200

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Prescription Prescription Required FormationFormulation: Tablet


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Stalevo 200 is a medication that is used to treat the symptoms of Parkinson's disease. It is typically prescribed for patients with advanced Parkinson's disease who require high doses of levodopa. It is a combination of three active ingredients: levodopa, carbidopa, and entacapone.

Levodopa is converted into dopamine in the brain, which helps to alleviate the symptoms of Parkinson's, while carbidopa helps prevent the breakdown of levodopa before it can reach the brain. Entacapone helps to prolong the effect of levodopa by slowing down its breakdown in the body.

Use and Dosage

Stalevo comes in the form of a tablet, typically taken 3 to 4 times a day, as prescribed by a doctor. Only take one tablet per dose, and swallow the tablet whole, without crushing, chewing, or splitting it. Doing so incorrectly may result in the wrong dose and can also cause staining of the mouth, dentures, and saliva.

To reduce nausea, Stalevo can be taken with food, but avoid a high-protein diet during treatment, unless directed otherwise by a doctor. Iron supplements or products containing iron should be taken as far apart in time from Stalevo as possible, as iron can reduce the medication's absorption by the body. Additionally, taking the medication with a high-fat, high-calorie meal can delay the onset of its effects by up to two hours.

The correct dosage of Stalevo will depend on the individual patient's medical condition and response to treatment, take it regularly and at the same time each day for maximum benefits.

Do not stop taking Stalevo tablets without consulting your doctor. Some conditions may become worse when the Stalevo is suddenly stopped. Also, if you suddenly stop using the medication, you may have withdrawal symptoms (such as anxiety, depression, confusion, fever, and muscle stiffness). To help prevent withdrawal, your doctor may lower your dose slowly. Withdrawal is more likely if you have used the tablet for a long time or in high doses.

Side Effect

Common Side Effects of Stalevo 200 (Carbidopa-Levodopa-Entacapone):

  • Agitation
  • Anxiety
  • Back pain
  • Blurred vision
  • Changes in your sense of taste
  • Constipation
  • Difficulty sleeping (insomnia)
  • Dizziness
  • Drowsiness
  • Dry mouth
  • Headache
  • Loss of appetite
  • Muscle cramps
  • Nausea
  • Skin rash or itching
  • Stomach pain or upset
  • Strange dreams
  • Unusual skin changes
  • Vomiting

Serious Side Effects of Stalevo 200 (Carbidopa-Levodopa-Entacapone):

  • Black or tarry stools
  • Blurred vision
  • Changes in the amount of urine
  • Chest pain
  • Confusion
  • Diarrhea
  • Difficulty breathing
  • Difficulty swallowing
  • Easy bleeding or bruising
  • Eye pain
  • Fainting
  • Fast or irregular heartbeat
  • Fever
  • Greatly increased eye blinking or twitching
  • Hallucinations
  • Hives
  • Involuntary movements (especially twitching of the eyelid)
  • Mental/mood changes (such as confusion hallucinations thoughts of suicide)
  • Muscle pain, tenderness, or weakness
  • New or worsening muscle spasms
  • Persistent diarrhea
  • Persistent sore throat
  • Rapid breathing and
  • Signs of infection (persistent sore throat)
  • Stomach/abdominal pain
  • Sweating
  • Swelling of your face lips tongue or throat
  • Thoughts of suicide
  • Tingling of the hands or feet
  • Unusual muscle stiffness
  • Unusual strong urges (increased gambling or sexual urges)
  • Unusual tiredness
  • Vision changes
  • Vomit that looks like coffee grounds

Forms and Strength

Stalevo 200 (Carbidopa-Levodopa-Entacapone) is available in the following forms and strength:

Stalevo 200: Tablet

  • 50/200/200mg


  • Allergic reactions: Patients who are allergic to levodopa, carbidopa, entacapone, or any of the other ingredients in Stalevo should not take the medication.
  • Cardiovascular events: Patients with a history of cardiovascular disease should be monitored closely while taking Stalevo, as it has been associated with an increased risk of cardiovascular events such as heart attack or stroke.
  • Dosage adjustments: The dosage of Stalevo may need to be adjusted in patients with liver or kidney problems, or in those taking certain medications.
  • Drinking alcohol: While taking Stalevo may increase the risk of side effects, such as drowsiness or dizziness. Talk to your healthcare provider about any potential interactions between alcohol and Stalevo before consuming alcohol while taking the medication.
  • Drug interactions: Stalevo may interact with other medications, consult a healthcare provider before taking it to avoid adverse effects.
  • Hallucinations and psychosis: Stalevo may cause hallucinations or psychosis, particularly in patients with a history of these conditions. If these symptoms occur, patients should seek medical attention immediately.
  • Impulse control disorders: Stalevo has been associated with the development of impulse control disorders, such as compulsive gambling or shopping. Patients should be instructed to report any unusual behavior to their healthcare provider.
  • Monitoring: Patients taking Stalevo should be monitored for changes in blood pressure, heart rate, and mental status.
  • Pregnancy and breastfeeding: Stalevo should be used with caution in pregnant or breastfeeding women, as its safety has not been established in these populations.
  • Side effects: Stalevo may cause side effects such as nausea, vomiting, dizziness, and dyskinesia.
  • Withdrawal symptoms: Abruptly discontinuing Stalevo may cause withdrawal symptoms such as muscle stiffness, fever, and confusion. Patients should be instructed to gradually taper off the medication under the supervision of a healthcare provider.

Frequently Asked Questions (FAQ)

Is Stalevo 200 suitable for all patients with Parkinson's disease?

Stalevo 200 is not suitable for everyone with Parkinson's disease. A doctor must assess individual needs and responses to determine if Stalevo 200 is an appropriate treatment option.

Can Stalevo 200 be taken with food?

Stalevo 200 should be taken with food to improve absorption and reduce nausea.

What should I do if I miss a dose of Stalevo 200?

If a dose of Stalevo 200 is missed, it should be taken as soon as possible. However, if it is close to the next scheduled dose, skip the missed dose and resume the regular dosing schedule.

How long does it take for Stalevo 200 to start working?

Stalevo 200 can start working within 30 minutes to an hour after taking it. However, individual response may vary, and the full effects of the medication can take several weeks to become apparent.


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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Stalevo 200 (Carbidopa/levodopa/entacapone). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Stalevo 200 (Carbidopa/levodopa/entacapone).