Prescription Required
Formulation: Prolonged Release Tablet
Prescription Required
Formulation: Prolonged Release Tablet
(Generic Alternative)
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Sinemet CR is a medication used to treat symptoms of Parkinson’s disease and syndrome. It is a combination of two active ingredients: carbidopa and levodopa.
Levodopa changes into dopamine in the brain, helping to control movement. Carbidopa prevents the breakdown of levodopa in the bloodstream so more levodopa can enter the brain. Carbidopa can also reduce some of levodopa’s side effects such as nausea and vomiting. The combination works together to increase dopamine levels in the brain, thereby improving movement and reducing symptoms such as tremors, stiffness, and difficulty moving.
Sinemet CR is a sustained-release formulation, which means it releases the medication slowly over time, allowing for more continuous and consistent symptom control.
Sinemet CR comes in the form of tablet to take by mouth with or without food as directed by your doctor, usually 2 to 3 times a day. Doses are usually taken 4 to 8 hours apart while awake. Doing so can release all the drug at once, increasing side effects risk. Swallow the whole or split tablet without crushing or chewing. Also, do not split the tablets unless they have a score line, and your doctor or pharmacist tells you to do so.
Taking Sinemet CR with food may help to decrease nausea. Avoid a high-protein diet (it decreases the amount of levodopa that your body takes in) during treatment, unless directed otherwise by your doctor. Separate your dose of this medication for as many hours as possible from any iron supplements or products containing iron (such as multivitamins with minerals) you may take. Iron can reduce the amount of this medication absorbed by the body. Consult your doctor or pharmacist for more details.
Use Sinemet CR tablet regularly to get the most benefit from it. To help you remember, take it at the same time each day. Do not stop taking Sinemet CR tablet without consulting your doctor. Some conditions may become worse when Sinemet CR is suddenly stopped. Also, if you suddenly stop using the tablet, you may have withdrawal symptoms (such as anxiety, depression, confusion, fever, muscle stiffness). To help prevent withdrawal, your doctor may lower your dose slowly. Withdrawal is more likely if you have used this medication for a long time or in high doses. Tell your doctor or pharmacist right away if you have withdrawal.
Sinemet CR (Carbidopa/Levodopa) is available in the following forms and strength:
Yes, Sinemet CR can interact with other medications, including antidepressants, antipsychotics, and blood pressure medications. Discuss all medications you are taking with your healthcare provider before starting Sinemet CR.
Sinemet CR is not typically used to treat Parkinson’s disease in children, and its safety and efficacy in children have not been well studied.
Sinemet CR is a controlled-release formulation of carbidopa/levodopa, which means it releases the medication over a longer period than regular Sinemet.
Yes, Sinemet CR can be used in combination with other medications such as dopamine agonists or MAO-B inhibitors, to improve motor symptoms of Parkinson’s disease.
| Generic name: | Carbidopa/Levodopa |
|---|---|
| Formulation: | CR Tablet, Prolonged Release Tablet |
| Strength(s): | 25/100mg, 50/200mg |
| Quantities Available: | 100 |
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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Sinemet CR (Carbidopa/Levodopa). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Sinemet CR (Carbidopa/Levodopa).
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