Eldepryl (Selegiline)

Indications

Eldepryl (generic name selegiline) is a medication used to treat the symptoms of Parkinson's disease. Eldepryl is a monoamine oxidase-B (MAO-B) inhibitor. It works by increasing dopamine levels in the brain, a neurotransmitter involved in regulating movement.

Eldepryl can be used in combination with other medications for Parkinson's disease. However, Eldepryl does not cure Parkinson's disease, but it can help improve symptoms such as stiffness, tremors, and difficulty with movement.

Use and Dosage

Selegiline, also known as Eldepryl, is usually taken orally twice daily with breakfast and lunch. Taking selegiline late in the day may interfere with sleep. Take the dosage as directed by your doctor based on your medical condition and response to therapy. Do not increase the dosage or take it more often than prescribed.

After taking selegiline for two to three days, your doctor may instruct you to lower your levodopa dose. Follow your doctor's instructions closely and do not stop or change the dose of any medication without consulting your doctor.

It may take several weeks before the full benefit of the medication is observed. Do not stop taking the drug without first consulting with your doctor. Do not take more or less of it or take it more often than prescribed as this can cause a sudden and dangerous increase in blood pressure.If the medication ceases to work effectively or if your condition worsens, speak with your doctor.

Side Effects

Common Side Effects of Eldepryl (Selegiline):

• Constipation
• Dizziness
• Mouth sores or ulcers
• Nausea
• Pain with swallowing
• Skin rash or other irritation
• Sleep problems
• Stomach pain

Serious Side Effects of Eldepryl (Selegiline):

• Agitation
• Anxiety
• Blurred vision
• Confusion
• Diarrhea
• Difficulty breathing
• Fainting
• Fast heart rate
• Fever
• Hallucinations
• Hives
• Increased sexual urges
• Increased tremors
• Lightheadedness
• Loss of coordination
• Nausea
• Overactive reflexes
• Pounding heartbeats
• Pounding in your neck or ears
• Seizure
• Severe chest pain
• Severe headache
• Shortness of breath
• Swelling of your face lips tongue or throat
• Uncontrolled muscle movements
• Unusual thoughts or behavior
• Unusual urges to gamble or other intense urges
• Vomiting
• Worsening side effects of your other medications

Forms and Strength

Eldepryl (Selegiline) is available in the following forms and strength:

Eldepryl: Tablet

• 5 mg
• 10 mg

Selegiline: Tablet

• 5 mg

Cautions

• Eldepryl may increase the risk of high blood pressure, so your blood pressure may need to be monitored regularly while taking this medication.
• Selegiline may interact with other medications, inform your doctor of all the medications you are taking, including prescription, over the counter, and herbal products.
• Eldepryl may cause dizziness or lightheadedness, avoid activities that require alertness until you know how the medication affects you.
• Eldepryl may cause side effects such as nausea, vomiting, and dry mouth, which may be bothersome for some people.
• Selegiline should not be taken with other medications that increase dopamine levels, such as levodopa, without the guidance of a doctor.
• Eldepryl may increase the risk of hallucinations or psychotic behavior, especially in elderly patients or those with a history of mental illness.
• Selegiline may cause a potentially life-threatening condition called serotonin syndrome when used with certain other medications, such as antidepressants. Symptoms of serotonin syndrome may include agitation, confusion, fever, sweating, and muscle stiffness.
• Eldepryl may cause a rare side effect called orthostatic hypotension, which is a sudden drop in blood pressure when standing up from a sitting or lying position. This may result in dizziness, lightheadedness, or fainting.
• Eldepryl should not be taken with other medications that also contain selegiline, as this may increase the risk of side effects or overdose.

Frequently Asked Questions (FAQ)

How long does it take for Eldepryl to start working?

The amount of time it takes for Eldepryl to start working may vary from person to person. It may take several weeks to see the full effects of the medication. Your doctor may adjust your dose or prescribe additional medications to improve your symptoms.

Is Eldepryl safe for everyone to take?

Eldepryl may not be safe for everyone to take, especially those with a history of mental illness, high blood pressure, or certain medical conditions. It may also interact with other medications.

Can Eldepryl be taken during pregnancy or while breastfeeding?

The effects of Eldepryl during pregnancy and breastfeeding are not well known. You should discuss any plans for pregnancy or breastfeeding with your doctor before taking this medication.

What should I do if I miss a dose of Eldepryl?

If you miss a dose of Eldepryl, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

Resources

• https://medlineplus.gov/druginfo/meds/a697046.html
• https://www.drugs.com/eldepryl.html
• https://www.webmd.com/drugs/2/drug-13490/eldepryl-oral/details
• https://www.rxlist.com/eldepryl-drug.htm
• https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/020647s006s007lbl.pdf
• https://www.goodrx.com/selegiline/what-is