Neuleptil (Pericyazine)

Indications

Neuleptil is an oral medication used to control symptoms of hostility, impulsiveness, and aggressiveness when used with other medications in adults and children over 5 years old.

Neuleptil contains the active ingredient periciazine and is typically prescribed for certain mental disorders such as psychosis. It is generally used to treat certain mental disorders such as psychosis. Neuleptil works by blocking dopamine receptors in the brain, which can help to reduce dopamine activity and stabilize mood.

Periciazine is available in oral form and requires several days to take effect. It has been the subject of several clinical trials studying its effectiveness in treating mood and behavior disorders.

Use and Dosage

Neuleptil comes in the form of Capsule to take orally by mouth, typically twice a day as prescribed by your doctor or pharmacist. Swallow the entire capsule and drink a glass of water afterward. If a different schedule is appropriate, they may suggest it. To maintain the beneficial effects, take it regularly and continuously.

Do not use Neuleptil tablet more than prescribed or stop using it suddenly, especially if you have been taking it for several weeks. If you are considering stopping the medication, talk to your doctor or pharmacist first.

To ensure the exact dosage, measure each dose with an accurate measuring device. If you forget a dose, take it as soon as you remember, unless it is almost time for the next dose. In that case, skip the missed dose. Doubling the next dose to catch up should be avoided.

Taking Neuleptil with food is recommended to avoid stomach irritation. Avoid spicy foods, coffee, or alcohol, as the latter may intensify the effect of this medication. Hence, avoid the consumption of alcohol or alcohol-containing products while taking this medication.

Side Effects

Common Side Effects of Neuleptil (Pericyazine):

• Dizziness
• Drowsiness
• Nausea
• Headache
• Dry mouth
• Weight changes
• Blurred vision
• Decreased interest in sex

Serious Side Effects of Neuleptil (Pericyazine):

• Abnormal movements
• Decrease in white blood cell count
• Irregular heart rhythm
• Seizures
• Fainting
• Chest pain
• Shortness of breath
• Neuroleptic malignant syndrome

Forms and Strength

Neuleptil (Pericyazine) is available in the following forms and strengths:

Neuleptil: Oral drops

• 5 mg
• 10 mg
• 10mg/mL

Cautions

• Neuroleptic Malignant Syndrome (NMS): Neuleptil may cause a rare, but serious condition called NMS, which can cause high fever, muscle stiffness, tremors, and other symptoms. Seek medical attention immediately if you experience any of these symptoms.
• Tardive dyskinesia: Long-term use of Neuleptil can cause tardive dyskinesia, a condition characterized by involuntary movements of the face and body. This condition may not go away even after stopping the medication.
• Cardiovascular effects: Neuleptil can cause changes in the heart rhythm, which can be serious or even life-threatening in some cases, particularly in predisposed patients with underlying heart conditions.
• Anticholinergic effects: Neuleptil can cause anticholinergic effects, such as dry mouth, constipation, blurred vision, and cognitive impairment.
• Use in elderly patients: Elderly patients may be at higher risk for developing tardive dyskinesia and other side effects due to the use of Neuleptil. The medication should be used with caution in this patient population.
• Pregnancy and breastfeeding: Neuleptil should only be used in pregnancy or breastfeeding if the benefits outweigh the potential risks, as it may cause harm to a developing fetus or infant.
• Hepatic and renal impairment: The medication should be used with caution in patients with liver or kidney problems, as it is eliminated from the body primarily through these organs.
• Seizures: Neuleptil may lower the seizure threshold and increase the risk of seizures in patients with a history of seizures or epilepsy.
• Hypotension: Neuleptil may cause a drop in blood pressure, especially upon standing or changing positions. Patients should be monitored for symptoms such as dizziness or lightheadedness.
• Interactions with other medications: Neuleptil may interact with other medications, including medications used to treat heart conditions, antihistamines, and certain antibiotics, among others.

Frequently Asked Questions (FAQ)

Can Neuleptil be stopped suddenly?

No, Neuleptil should not be stopped suddenly without first consulting with a healthcare provider. Abruptly stopping the medication can cause withdrawal symptoms and possibly worsen the underlying condition.

Is it safe to operate heavy machinery while taking Neuleptil?

Neuleptil may cause drowsiness, dizziness, or other side effects that can impair your ability to operate heavy machinery or perform other tasks that require mental alertness. You should avoid driving or operating heavy machinery until you know how the medication affects you.

Are there any dietary restrictions while taking Neuleptil?

There are no specific dietary restrictions while taking Neuleptil but maintain a healthy diet and exercise regularly to help manage potential weight gain associated with the medication.

How long does it take for Neuleptil to work?

The onset of action of Neuleptil can vary depending on the patient and the condition being treated. It may take several weeks to see the full benefits of the medication.

Is Neuleptil addictive?

This type of medication does not come with the potential for abuse or addiction. This is also not classified as a controlled substance. However, self-medication and taking this drug more frequently than prescribed can cause drug dependence.

Resources

• https://www.iamentalhealth.ca/Get-Help/Resources/Medication-Resource-Centre/Specific-Antipsychotic-Medications/Neuleptil-(periciazine)
• https://www.uniprix.com/en/drug-lexicon/01926756/neuleptil
• https://myhealth.alberta.ca/Health/medications/Pages/conditions.aspx?hwid=fdb1287
• https://www.rxfiles.ca/rxfiles/uploads/documents/dementia-newsletter-overview-booklet-web.pdf