Indications
Tirosint is a medication used to treat hypothyroidism, or an underactive thyroid. It contains levothyroxine sodium. Levothyroxine is a synthetic version of the thyroid hormone thyroxine (T4) and is typically taken orally as a capsule. It replaces or provides more thyroid hormone, which is normally produced by the thyroid gland. Levothyroxine helps to restore normal levels of hormones in the body and can help improve symptoms associated with these conditions.
Levothyroxine is used to replace the hormone that is not being produced by the thyroid gland in sufficient quantities, which can cause symptoms such as fatigue, weight gain, cold intolerance, and dry skin. When taken as prescribed, levothyroxine can help patients manage their symptoms and improve their quality of life.
Uses and Dosage
Levothyroxine oral should be taken on an empty stomach, 30 to 60 minutes before breakfast for optimal efficacy. Swallow the capsule whole with a full glass (8 ounces) of water to prevent the tablet from dissolving too quickly and potentially swelling in your throat. Follow the dosing instructions provided by your healthcare provider and take the medication at the same time each day.
The dosage of Tirosint can vary depending on factors such as age, weight, and medical history, and should be determined by a healthcare provider. The recommended starting dose for adults with hypothyroidism is typically between 50 and 100 micrograms once a day, which may be gradually increased over several weeks. The recommended full replacement dose for adults diagnosed with hypothyroidism is around 1.6 mcg/kg/day based on ideal body weight or lean body mass.
Side Effect
Common Side Effects of Tirosint (Levothyroxine):
- Changes in appetite or changes in weight
- Changes in menstrual periods, and temporary hair loss
- Fever
- Headache
- Hot flashes
- Irritability
- Nausea
- Nervousness
- Sensitivity to heat
- Sleep problems (insomnia)
- Sweating
Serious Side Effects of Tirosint (Levothyroxine):
- Appetite changes
- Chest pain
- Dryness of your skin or hair
- Fast or irregular heartbeats
- Feeling depressed or irritable
- Feeling nervous or irritable
- Fever
- Hot flashes and sweating
- Irregular menstrual periods
- Memory problems
- Pain spreading to your jaw or shoulder
- Shortness of breath
- Sleep problems (insomnia)
- Tiredness
- Tremors
- Weakness
- Weight changes
Form and Strength
Tirosint (Levothyroxine) is available in the following forms and strength:
Tirosint: Capsule
- 0.050 mg
- 0.075 mg
- 0.100 mg
- 0.1120 mg
Caution
- Tirosint can interact with other medications, tell a healthcare provider about all medications (prescription and over the counter) and supplements being taken before starting Tirosint.
- It should only be used under the supervision of a healthcare provider and never for the treatment of obesity or weight loss.
- It should not be used by people with certain medical conditions, such as thyrotoxicosis or uncorrected adrenal problems.
- It can interact with other medications, tell a healthcare provider about all medications (prescription and over the counter) and supplements being taken before starting Tirosint.
- The dosage may need to be adjusted during pregnancy or in people with certain medical conditions, such as cardiovascular disease, diabetes, or malabsorption.
- Before taking levothyroxine, tell your doctor or pharmacist if you are allergic to it or if you have any other allergies. It may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Frequently Asked Questions (FAQ)
How long does Tirosint stay in your system?
The half-life of levothyroxine (including Tirosint) is about 6 to 7 days, meaning it can take several weeks for the medication to be fully eliminated from your system.
How long does it take for Tirosint to start working?
It may take several weeks for the full effects of Tirosint (or any form of levothyroxine) to be realized.
Can Tirosint cause weight loss?
Although weight loss can be a side effect of Tirosint in people taking it for low thyroid levels (hypothyroidism), it is not a guaranteed effect and may not be desirable for everyone.
Can iodine supplements help with hypothyroidism?
If the underactive thyroid is not caused by iodine deficiency, then iodine supplements give no benefit and should not be taken.
How should Tirosint be taken?
Tirosint should be taken on an empty stomach, either 30 minutes to 1 hour before breakfast or at bedtime, at least 3 hours after the last meal.
Can Tirosint be taken during pregnancy?
Yes, Tirosint can be taken during pregnancy, although the dosage may need to be adjusted.
Resources
- https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5d378add-f13d-40f2-99dc-0f2340ab44b7
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/022121lbl.pdf
- https://www.drugs.com/levothyroxine.html#side-effects
- https://www.rxlist.com/synthroid_vs_tirosint/drugs-condition.htm
- https://www.webmd.com/drugs/2/drug-153788/tirosint-oral/details
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