Cytomel (Liothyronine)

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Cytomel Brand
Dosage Quantity & Price
Liothyronine (Generic alternate to Cytomel) Generic
Dosage Quantity & Price
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Table of contents:

Cytomel generically known as Liothyronine is a prescription medication used to treat symptoms of low thyroid hormone (hypothyroidism), an enlarged thyroid gland (nontoxic goiter), myxedema, and myxedema coma. Cytomel belongs to a class of drugs known as thyroid products, which are used to help regulate the body's levels of thyroid hormones. Liothyronine works by replacing the missing or deficient thyroid hormones that are normally produced in the body.

It may be used alone or in combination with other medications. Cytomel may be used to treat conditions such as myxedema coma, a severe form of hypothyroidism, as well as other types of thyroid disorders. It can also be used to test for thyroid problems and as an adjunct to radioiodine therapy in the management of thyroid cancer. Additionally, it can be used to reduce the size of nodular goiters and to treat certain types of obesity.

Uses and Dosage

Cytomel is taken orally in tablet form and should be taken as prescribed by your doctor. take Cytomel regularly to get the most benefit from it, and it should not be stopped without first consulting with your doctor since thyroid replacement treatment is usually taken for life.

The dosage of Cytomel is based on your medical condition, age, lab test results, and response to treatment. Your doctor may need to adjust your dosage over time to ensure you are getting the most benefit from the medication.

  • For hypothyroidism, the recommended dosage range of Cytomel is 25 to 75 mcg once daily.
  • For thyroid cancer, the dose will depend on the target TSH (thyroid stimulating hormone) level set by your provider.
  • For thyroid suppression tests, Cytomel is typically taken at a dose of 75 to 100 mcg once daily for 7 days.

Side Effects

Common Side Effects of Liothyronine:

  • Constipation
  • Diarrhea
  • Headache
  • Indigestion
  • Nausea
  • Sleep problems or insomnia

Serious Side Effects of Cytomel:

  • Anxiety
  • Excessive sweating
  • Fatigue
  • Fever
  • Hunger
  • Insomnia
  • Nervousness
  • Weight loss
  • Irritability
  • Heart palpitations
  • Chest pain
  • Diarrhea
  • Menstrual irregularities
  • Increased appetite

Form and Strength

Cytomel (Liothyronine) is available in the following forms and strengths:

Cytomel: Tablet

  • 5 mcg
  • 25mcg

Liothyronine: Tablet

  • 5 mcg
  • 25 mcg


  • Before taking liothyronine, tell your doctor or pharmacist if you are allergic to it or have any other allergies. This product may contain inactive ingredients that can cause allergic reactions or other problems. Speak to your pharmacist for more information.
  • Taking liothyronine may cause an increase in blood pressure, heart rate, and heart-related events, so it is important to alert your doctor if you have any of these conditions. Additionally, liothyronine may increase your risk of developing diabetes, so discuss any changes in your blood sugar levels with your doctor.
  • When taking Cytomel (liothyronine), check your blood sugar levels as directed by your healthcare provider. If the levels are unusual, it may be necessary to increase the doses of your medications.
  • Taking Cytomel (liothyronine) can weaken bones over time, particularly in postmenopausal women. To reduce this risk, your healthcare provider will monitor your thyroid levels and adjust your dose as needed to ensure that you are taking the lowest effective dose.
  • Cytomel should not be used for the treatment of obesity or for weight loss. It is ineffective for weight reduction and when used for this purpose may result in serious side effects. Note that taking this medication may cause other symptoms such as weight gain, constipation, and a slow heart rate.

Frequently Asked Questions (FAQ)

How does Cytomel work?

Cytomel works by supplementing the body's natural production of T3 thyroid hormones, which helps to regulate metabolism and other processes in the body.

What is the best time to take liothyronine?

It is best to take on an empty stomach, at least 30 minutes before or 2 hours after food. Follow the directions on the prescription label. Take it at the same time each day. Do not take your medication more often than directed.

How long does Cytomel take to start working?

Cytomel starts working within a few hours, but its maximum effect can take two to three days to occur. It only takes 4 hours for 95% of a dose of Cytomel to be totally absorbed.

Is Cytomel safe to use?

Cytomel is generally considered to be a safe and effective medication when used correctly and as directed by a healthcare professional. As with any medication, discuss any risks and side effects with your doctor before starting treatment.

How long does Cytomel last?

The half-life of Cytomel is about 2.5 days and experts agree that it takes up to 5 half-lives for a drug without active metabolites to be completely removed from the body. This calculates out to 12.5 days for Cytomel.


It's important to purchase Cytomel from verified Canadian pharmacy.

Additional information

Generic name:

L-Triidotironin Sodium, Liothyronine, Triiodothyronine




5mcg, 25mcg

Quantities Available:

90, 100, 300