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Zaroxolyn contains the active ingredient metolazone. It is a prescription medication used to reduce extra fluid in the body and to help lower high blood pressure.
Zaroxolyn is used to treat edema, which means swelling caused by too much fluid in the body.
It may be prescribed when edema is related to conditions such as:
By helping the body remove extra salt and water, Zaroxolyn can reduce swelling in areas such as the legs, ankles, and feet.
Zaroxolyn may also be used to treat high blood pressure.
It may be taken alone or together with other blood pressure medications.
Lowering blood pressure can help reduce the long-term risk of problems such as stroke, heart attack, and kidney damage.
Zaroxolyn belongs to a group of medications called thiazide-like diuretics, sometimes called water pills.
It helps the kidneys remove more sodium and water through the urine.
This reduces the amount of extra fluid in the body and can also help lower blood pressure.
Zaroxolyn can also affect electrolytes such as potassium and sodium.
Your healthcare provider may order blood tests during treatment to monitor your electrolyte levels, kidney function, and response to the medication.
Zaroxolyn comes as a tablet that is taken by mouth, usually once daily.
Take it at about the same time each day and exactly as prescribed by your healthcare provider.
For mild to moderate high blood pressure, the usual dose is:
2.5 to 5 mg once daily.
Your healthcare provider will choose the lowest dose that controls your blood pressure effectively.
For swelling caused by heart failure or kidney disease, the usual dose is:
5 to 20 mg once daily.
The exact dose depends on how much fluid you are retaining and how well you respond to treatment.
The dose of Zaroxolyn is individualized.
Your healthcare provider may adjust it based on:
The goal is to use the lowest effective dose that controls your symptoms.
When Zaroxolyn is used for edema, increased urination may begin within about 1 hour after a dose and can continue for 24 hours or longer.
For high blood pressure, it may take several days or longer to see the full effect.
Take Zaroxolyn every day as prescribed, even if you feel well.
High blood pressure often does not cause noticeable symptoms, so the medication may still be working even when you do not feel any different.
Do not take more or less Zaroxolyn than prescribed.
Taking too much can cause excessive fluid loss or electrolyte problems, while taking too little may not adequately control your blood pressure or swelling.
Do not stop taking Zaroxolyn without speaking with your healthcare provider.
Zaroxolyn (Metolazone) is available in the following forms and strength:
Do not take Zaroxolyn if you are allergic to metolazone or any ingredient in the medication.
Seek medical attention if you develop:
Zaroxolyn can cause changes in electrolytes, especially potassium and sodium.
Low potassium may cause:
Low sodium may cause:
Your healthcare provider may order blood tests to monitor your electrolyte levels during treatment.
Because Zaroxolyn removes extra fluid from the body, it can sometimes cause dehydration or low blood pressure.
You may feel:
Stand up slowly from a sitting or lying position.
Contact your healthcare provider if you develop severe dizziness, fainting, very dry mouth, or a large decrease in urination.
Tell your healthcare provider if you have kidney disease.
Zaroxolyn can affect kidney function, especially if you become dehydrated or take other medicines that affect the kidneys.
Your healthcare provider may monitor your kidney function during treatment.
Zaroxolyn should be used carefully in people with liver disease.
Changes in fluid and electrolyte levels may be more serious in people with severe liver problems.
Tell your healthcare provider if you have cirrhosis or another significant liver condition.
Zaroxolyn may raise blood sugar levels.
If you have diabetes, you may need closer monitoring of your blood glucose while taking this medication.
Your diabetes treatment may need to be adjusted if your blood sugar changes significantly.
Zaroxolyn may raise uric acid levels in the blood.
This can trigger or worsen gout in some people.
Tell your healthcare provider if you have gout or a history of high uric acid levels.
Zaroxolyn can interact with several medications.
Important examples include:
Tell your healthcare provider about all prescription medications, over-the-counter products, vitamins, supplements, and herbal products you use.
Taking Zaroxolyn with lithium can increase lithium levels and raise the risk of toxicity.
If both medications are needed, your healthcare provider may monitor lithium levels closely.
Low potassium caused by Zaroxolyn can increase the risk of side effects from digoxin, including abnormal heart rhythms.
Your healthcare provider may monitor your potassium level and heart function if you take both medicines.
Tell your healthcare provider if you are pregnant or planning to become pregnant.
Your healthcare provider will decide whether Zaroxolyn is appropriate based on your condition and the expected benefits and risks.
Metolazone can pass into breast milk.
Tell your healthcare provider if you are breastfeeding so they can determine whether Zaroxolyn is appropriate for you.
Older adults may be more sensitive to dehydration, low blood pressure, electrolyte changes, and kidney problems.
Closer monitoring or a lower dose may sometimes be needed.
Contact your healthcare provider promptly if you develop muscle cramps, severe weakness, confusion, repeated vomiting, fainting, an irregular heartbeat, or a significant decrease in urination.
These symptoms may be signs of dehydration, an electrolyte imbalance, or another serious reaction.
Zaroxolyn is a thiazide-like diuretic, also called a water pill. It belongs to a chemical group called quinazolines and works in a similar way to thiazide diuretics by helping the kidneys remove extra sodium and water from the body.
Zaroxolyn can begin increasing urination within about 1 hour after a dose. Its effect on fluid retention may continue for 24 hours or longer. You may notice swelling improve over the next several days, while the full blood pressure-lowering effect can take longer.
Metolazone is usually taken once daily. Try to take it at about the same time each day and follow your healthcare provider’s instructions carefully. Do not take extra doses or take it more often than prescribed.
No. Metolazone is not a weight-loss medication. It removes excess fluid from the body, so your weight may decrease if you have swelling caused by heart failure, kidney disease, or another condition that causes fluid retention. This is a loss of excess water, not body fat. Do not use Zaroxolyn for weight loss unless it has been prescribed for a medical condition.
| Generic name: | Metolazone |
|---|---|
| Formulation: | Tablet |
| Strength(s): | 2.5mg, 5mg |
| Quantities Available: | 90, 100 |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Zaroxolyn (metolazone) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.
Here’s what you need to know:
Dosage and Quantity: Zaroxolyn is commonly prescribed in dosages of 2.5 mg, taken once daily. For a 90-day supply, this means you would order 90 tablets (90 days x 1 tablet per day).
Yes, we sell metolazone on our website. You can enjoy low prices when you order through us. To purchase metolazone, you will need a valid prescription from your healthcare provider. We require this prescription to dispense the medication safely and appropriately. You have the option to submit your prescription by mailing it to us, faxing it, or uploading it through your online account.
Yes, we ship Zaroxolyn (metolazone) to both the United States and Puerto Rico.
Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Zaroxolyn (Metolazone). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Zaroxolyn (Metolazone).
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