Roszet (Ezetimibe/rosuvastatin) Shopper Approved

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Roszet is a prescription medication indicated in adults as an adjunct to diet to help lower "bad" cholesterol, such as LDL. It is intended for use in patients with primary non-familial hyperlipidemia. Roszet is a combination medication that contains two active ingredients, rosuvastatin and ezetimibe.

Rosuvastatin is an HMG CoA-reductase inhibitor (statin) that works by reducing the production of cholesterol in the liver, while ezetimibe is a dietary cholesterol absorption inhibitor that works by reducing the amount of cholesterol absorbed by the small intestine.

Use and Dosage

Roszet comes in the form of tablet to take by mouth with or without food as directed by your doctor, usually once daily. Swallow the tablets whole. Do not crush, chew, or dissolve tablets. If you are taking a bile acid sequestrant (such as cholestyramine or colestipol), take this product at least 2 hours before or at least 4 hours after taking the bile acid sequestrant.

To ensure maximum absorption, take bile acid sequestrants, such as cholestyramine and colestipol, at least 2 hours before or 4 hours after taking Roszet. Avoid taking antacids containing aluminum and magnesium at the same time as Roszet, as they can reduce its absorption.

Take Roszet regularly to get the most benefit from it. To help you remember, take it at the same time each day. Keep taking Roszet even if you feel well. Most people with high cholesterol do not feel sick. Continue to follow your doctor's advice about diet and exercise. It may take up to 4 weeks before you get the full benefit of this product.

Side Effects

Common Side Effects of Roszet (Ezetimibe/rosuvastatin):

  • Common cold and flu
  • Constipation
  • Diarrhea
  • Dizziness
  • Headache
  • Joint pain
  • Muscle aches and pains
  • Nausea
  • Pain (back, hands, or legs)
  • Runny nose and sore throat
  • Stomach pain
  • Tiredness
  • Weakness

Serious Side Effects of Roszet (Ezetimibe/rosuvastatin):

  • Dark-colored urine
  • Jaundice (yellowing of the skin or eyes)
  • Serious eye symptoms such as: sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights
  • Serious heart symptoms include: fast, irregular, or pounding heartbeats; fluttering in the chest; shortness of breath; sudden dizziness, lightheadedness, or passing out
  • Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors
  • Severe weakness or tiredness
  • Unexplained muscle pain, tenderness, or weakness (especially if you also have a fever)
  • Upper stomach pain, and loss of appetite

Forms and Strength

Roszet (Ezetimibe/rosuvastatin) is available in the following forms and strength:

Roszet: Tablet

  • 5/10mg
  • 10/10mg
  • 20/10mg


  • Hypersensitivity: Roszet should not be used in patients who are hypersensitive to rosuvastatin, ezetimibe, or any of its excipients.
  • Liver disease: Roszet should be used with caution in patients with liver disease because it can worsen liver function.
  • Muscle problems: Roszet can cause severe muscle pain and damage, particularly in patients who take high doses of the drug or have pre-existing muscle problems.
  • Pregnancy and breastfeeding: Roszet should not be used during pregnancy or breastfeeding, as it can harm the fetus or the nursing baby.
  • Renal impairment: Roszet should be used with caution in patients with severe renal impairment.
  • Concomitant use with cyclosporine: Concomitant use of Roszet with cyclosporine can increase the risk of side effects.
  • Alcohol consumption: Patients should avoid consuming large amounts of alcohol while taking Roszet, as it can increase the risk of liver problems.
  • Thryoid disease: Roszet may increase thyroid-stimulating hormone (TSH) levels in patients with pre-existing thyroid disease.
  • Concomitant use with certain medications: Roszet can interact with certain medications, including fibrates, niacin, and some HIV protease inhibitors.
  • Pediatric use: The safety and efficacy of Roszet in pediatric patients have not been established.

Frequently Asked Questions (FAQ)

Can I stop taking Roszet on my own?

No, you should not stop taking Roszet without consulting your healthcare provider first, as sudden discontinuation can cause your cholesterol levels to increase.

How long does it take for Roszet to start working?

Roszet may start working to lower cholesterol levels within a few weeks, but it typically takes several weeks or months to see the full effects.

Can Roszet be taken with food?

Yes, Roszet can be taken with or without food. However, some people find it easier to remember to take it with a meal.

Can Roszet cause weight gain?

Weight gain is not a common side effect of Roszet.


Additional information

Generic name:





5/10mg, 10/10mg, 20/10mg

Quantities Available:

30, 90


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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Roszet (Ezetimibe/rosuvastatin). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Roszet (Ezetimibe/rosuvastatin).