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Prescription Prescription Required FormationFormulation: Capsule

Sinequan

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Prescription Prescription Required FormationFormulation: Capsule

Doxepin Hydrochloride

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Sinequan contains the active ingredient doxepin hydrochloride. It is a prescription medication used to treat certain types of depression and anxiety.

Depression

Sinequan may be used to treat depression, including major depressive disorder.

Depression can affect how you feel, think, sleep, eat, and handle everyday activities. Symptoms may include:

  • Ongoing sadness
  • Loss of interest in activities you usually enjoy
  • Low energy
  • Trouble sleeping
  • Difficulty concentrating
  • Changes in appetite
  • Feelings of hopelessness or worthlessness

Sinequan may help improve these symptoms over time.

Anxiety

Sinequan may also be used to treat anxiety, including anxiety that occurs along with depression.

Anxiety can cause symptoms such as:

  • Excessive worry
  • Nervousness
  • Restlessness
  • Feeling tense or on edge
  • Trouble sleeping
  • Difficulty concentrating

Sinequan may help reduce these symptoms and improve your overall sense of well-being.

How Sinequan Works

Sinequan belongs to a group of medications called tricyclic antidepressants (TCAs).

It works by increasing the activity of certain natural chemicals in the brain, especially serotonin and norepinephrine. These chemicals play an important role in mood, emotions, and anxiety.

By helping keep more serotonin and norepinephrine available in the brain, Sinequan may help improve mood and reduce anxiety symptoms.

Other Effects of Sinequan

Sinequan also affects other chemical receptors in the body, including histamine receptors.

Because of this, it may cause side effects such as:

  • Drowsiness
  • Dry mouth
  • Constipation
  • Dizziness

These effects can vary from person to person.

When Improvement May Be Noticed

Some symptoms, such as sleep problems or anxiety, may begin to improve earlier in treatment.

However, it may take several weeks to feel the full effect on depression or overall mood.

Continue taking Sinequan as prescribed even if you do not notice improvement right away.

Sinequan vs. Low-Dose Doxepin for Sleep

Sinequan should not be confused with low-dose doxepin products such as Silenor.

Both medications contain doxepin, but they are used differently.

Sinequan is generally used at higher doses to treat depression and anxiety, while Silenor is used at much lower doses to help people stay asleep.

Do not switch between these products unless your healthcare provider tells you to.

Sinequan is taken by mouth as directed by your healthcare provider.

Your dose depends on the condition being treated, how severe your symptoms are, how well you respond to treatment, and whether you develop side effects.

Sinequan may be taken in divided doses throughout the day or as a single daily dose, depending on the dose prescribed. If it is taken once daily, your healthcare provider may recommend taking it at bedtime because the medication can cause drowsiness.

Your Dose May Be Increased Gradually

Your healthcare provider may start you at a lower dose and gradually increase it.

Starting with a lower dose can help reduce side effects such as:

  • Drowsiness
  • Dizziness
  • Dry mouth
  • Constipation

Do not increase your dose, take Sinequan more often, or use it for longer than prescribed.

Take Sinequan Regularly

Take Sinequan at about the same time each day.

Taking it regularly helps maintain a consistent amount of medication in your body and gives it the best chance to work properly.

Continue taking Sinequan even if you begin to feel better. Do not stop treatment on your own.

Swallow the Capsules as Directed

Swallow Sinequan capsules with water.

If you have difficulty swallowing the capsules, speak with your healthcare provider or pharmacist rather than opening or changing the capsules on your own.

Instructions about diluting doxepin with water, juice, or other liquids apply to certain liquid formulations of doxepin, not to Sinequan capsules.

When Improvement May Be Noticed

Some symptoms, such as anxiety or sleep problems, may begin to improve earlier in treatment.

However, it may take 2 to 3 weeks or longer to experience the full antidepressant effect.

Continue taking Sinequan as prescribed even if you do not notice improvement right away.

Do Not Stop Sinequan Suddenly

Do not suddenly stop taking Sinequan unless your healthcare provider tells you to.

Stopping treatment too quickly may cause symptoms such as:

  • Headache
  • Nausea
  • Tiredness
  • Irritability
  • Changes in mood
  • Sleep problems

Your original symptoms may also return or become worse.

When Sinequan needs to be stopped, your healthcare provider may gradually reduce your dose.

What to Do If You Miss a Dose

If you miss a dose of Sinequan, take it when you remember unless it is almost time for your next scheduled dose.

If your next dose is approaching, skip the missed dose and continue with your regular schedule.

Do not take two doses at the same time or take extra Sinequan to make up for a missed dose.

Tell Your Healthcare Provider About Other Medications

Before taking Sinequan, tell your healthcare provider about all medications and supplements you use, including:

  • Prescription medications
  • Over-the-counter medications
  • Vitamins
  • Herbal products

Some medications can interact with Sinequan and may increase the risk of side effects.

Follow Your Healthcare Provider’s Instructions

Take Sinequan exactly as prescribed and attend any recommended follow-up appointments.

Contact your healthcare provider if your symptoms become worse, you experience concerning side effects, or you notice significant changes in your mood or behavior.

Common Side Effects of Sinequan (Doxepin Hydrochloride):

  • Blurred vision
  • Constipation
  • Diarrhea
  • Dizziness
  • Drowsiness
  • Dry mouth
  • Headache
  • Nausea
  • Trouble passing urine

Serious Side Effects of Sinequan (Doxepin Hydrochloride):

  • Changes in blood pressure
  • Rapid or worm-like movements of the tongue
  • Rapid weight gain
  • Redness of the face, neck, arms, and occasionally, upper chest
  • Restlessness
  • Ringing or buzzing or other unexplained noise in the ears
  • Skin rash
  • Sudden loss of consciousness
  • Sweating
  • Swelling of the face, ankles, or hands
  • Swollen glands
  • Unusual bleeding or bruising
  • Unusual tiredness or weakness
  • Vomiting
  • Vomiting of blood
  • Weight gain
  • Yellow eyes or skin

Sinequan (Doxepin Hydrochloride) is available in the following forms and strengths:

Sinequan: Capsule

  • 10 mg
  • 25 mg
  • 50 mg
  • 75 mg
  • 100 mg

Doxepin Hydrochloride: Capsule

  • 25 mg
  • 75 mg

Suicidal Thoughts and Behavior

Sinequan may increase the risk of suicidal thoughts or behavior in some children, adolescents, and young adults, especially when treatment is first started or the dose is changed.

Patients should be monitored for:

  • Worsening depression
  • New or unusual changes in mood
  • Agitation or restlessness
  • Suicidal thoughts or behavior

Contact a healthcare provider right away if any of these symptoms occur.

Drowsiness and Reduced Alertness

Sinequan can cause drowsiness, dizziness, slowed thinking, or reduced coordination.

Until you know how the medication affects you, avoid driving, operating machinery, or doing other activities that require full alertness.

Alcohol and other medications that cause drowsiness can make these effects stronger.

Seizure Risk

Sinequan may lower the seizure threshold in some people.

Tell your healthcare provider if you have a history of seizures or take medications that may also increase seizure risk.

Urinary Retention

Sinequan can make it more difficult to urinate.

Tell your healthcare provider if you have a history of urinary retention, an enlarged prostate, or other urinary problems.

Contact your healthcare provider if you develop difficulty starting urination, weak urine flow, or an inability to empty your bladder.

Glaucoma

Sinequan can increase pressure inside the eye in people who are at risk for certain types of glaucoma.

Tell your healthcare provider if you have glaucoma, especially narrow-angle glaucoma.

Seek prompt medical attention if you develop severe eye pain, blurred vision, halos around lights, or sudden vision changes.

Anticholinergic Side Effects

Sinequan can cause anticholinergic side effects, including:

  • Dry mouth
  • Constipation
  • Blurred vision
  • Urinary retention
  • Confusion

These effects may be more noticeable in older adults or people who are sensitive to anticholinergic medications.

Heart Problems

Sinequan should be used carefully in people with cardiovascular disease.

Tricyclic antidepressants can affect heart rhythm and electrical conduction.

Tell your healthcare provider if you have:

  • An irregular heartbeat
  • Heart block
  • A history of heart attack
  • Other significant heart disease

Sinequan is generally not recommended during the immediate recovery period after a heart attack.

Liver Problems

Tell your healthcare provider if you have liver disease.

Because doxepin is processed by the liver, liver impairment may increase the amount of medication in the body and raise the risk of side effects.

A lower dose or closer monitoring may be needed.

Kidney Problems

Tell your healthcare provider if you have kidney disease.

Kidney problems do not always require a specific dose adjustment, but your healthcare provider may still consider your kidney function, age, other medical conditions, and medications when choosing the dose.

Drug Interactions

Sinequan can interact with many medications and substances.

Important interactions may occur with:

  • Other antidepressants
  • Monoamine oxidase inhibitors (MAOIs)
  • Sedatives
  • Sleeping medications
  • Opioids
  • Antihistamines
  • Anticholinergic medications
  • Alcohol

Tell your healthcare provider about all prescription medications, over-the-counter products, vitamins, supplements, and herbal products you use.

Do not start or stop another medication without checking with your healthcare provider.

MAO Inhibitors

Sinequan should not be taken together with an MAOI.

Using these medications too close together can cause serious or potentially life-threatening reactions.

A waiting period is usually required when switching between Sinequan and an MAOI.

Do Not Stop Sinequan Suddenly

Do not stop taking Sinequan suddenly unless your healthcare provider tells you to.

Stopping too quickly may cause symptoms such as:

  • Nausea
  • Headache
  • Dizziness
  • Trouble sleeping
  • Irritability
  • Tiredness

Your original symptoms may also return or become worse.

Your healthcare provider may recommend gradually reducing the dose before treatment is stopped.

What should I do if I experience severe side effects from Sinequan?

Seek immediate medical attention if you develop serious symptoms such as a seizure, trouble breathing, fainting, a very fast or irregular heartbeat, severe confusion, or swelling of the face, lips, tongue, or throat. You should also contact a healthcare provider promptly if you notice severe mood changes or thoughts of self-harm.

Can Sinequan be taken during pregnancy or while breastfeeding?

Tell your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. Sinequan may be used during pregnancy only when the potential benefits outweigh the possible risks. Your healthcare provider will consider your condition, treatment needs, and available alternatives before recommending it. Doxepin can pass into breast milk and may cause serious side effects in a nursing infant, including excessive sleepiness or breathing problems. Breastfeeding is generally not recommended while taking Sinequan.

How long does it take for Sinequan to start working?

Some symptoms, such as anxiety or sleep problems, may begin to improve earlier in treatment. However, it may take 2 to 3 weeks or longer to experience the full antidepressant effect. Continue taking Sinequan exactly as prescribed, even if you do not notice improvement right away.

What should I do if I miss a dose of Sinequan?

If you miss a dose of Sinequan, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time or take extra Sinequan to make up for the missed dose.

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Additional Information Book
Generic name:

Doxepin, Doxepin Hydrochloride

Formulation:

Capsule

Strength(s):

10mg, 25mg, 50mg, 75mg, 100mg

Quantities Available:

100

Why customers love Online Pharmacies Canada

Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.

Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.

How to Order

How much Sinequan can I order at once from a Canadian pharmacy?

When ordering Sinequan (doxepin hydrochloride) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.

Here’s what you need to know:

Dosage and Quantity: Sinequan is commonly prescribed in dosages of 10 mg, 25 mg, 50 mg, or 100 mg, taken once daily or in divided doses. For example, if prescribed at a standard dose of 100 mg once daily, then for 90-day supply, you would order 90 capsules (90 days x 1 capsule per day).

Do you sell doxepin hydrochloride?

Yes, we sell doxepin hydrochloride on our website. You can enjoy low prices when you order through us. To purchase doxepin hydrochloride, you will need a valid prescription from your healthcare provider. We require this prescription to dispense the medication safely and appropriately. You have the option to submit your prescription by mailing it to us, faxing it, or uploading it through your online account.

Do you offer shipping of Sinequan (doxepin hydrochloride) to the United States?

Yes, we ship Sinequan (doxepin hydrochloride) to both the United States and Puerto Rico.

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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Sinequan (Doxepin Hydrochloride). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Sinequan (Doxepin Hydrochloride).