Protonix (Pantoprazole)

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Protonix Brand
Dosage Quantity & Price
Pantoprazole (Generic alternate to Protonix) Generic
Dosage Quantity & Price
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Table of contents:

Protonix (Pantoprazole) is a prescription medication used in the treatment of a variety of digestive conditions. It belongs to a class of drugs known as proton pump inhibitors (PPIs), which work by reducing acid production in the stomach. Pantoprazole is used to treat symptoms such as heartburn, difficulty swallowing, and persistent cough associated with gastroesophageal reflux disease (GERD).

Protonix is a proton pump inhibitor (PPI) drug prescribed by medical professionals to treat acid-related damage to the esophagus. It has been approved for short-term use, and although it may help with other acid-related conditions, its primary purpose is to heal esophageal damage caused by acid reflux. Patients should not take Protonix if they are looking for immediate relief of heartburn symptoms as it will not work quickly enough.

Uses and Dosage

Pantoprazole is available in the form of a tablet that needs to be taken orally once a day, as directed by your doctor. To ensure the effectiveness of the medication, it is important to swallow the tablet whole without crushing, chewing, or breaking it down. Your doctor may recommend that you take Pantoprazole 1 to 4 times a day or a single dose every other day.

To ensure that you take the medication as directed, it is advisable to set reminders in your calendar. Do not discontinue this medication without first consulting with your doctor, as some conditions may become worse if the drug is suddenly stopped. The dose may need to be gradually reduced. The dosage and duration of treatment for Pantoprazole are determined by your medical condition and response to treatment.

The dose of this medicine will be different for different patients. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For Gastroesophageal Reflux Disease (GERD):
    • Adults: 40 milligrams (mg) once a day for up to 8 weeks. Your doctor may want you to take pantoprazole for more than 8 weeks for certain conditions.
    • Children 5 years of age and older weighing 40 kilograms (kg) or more 40 mg once a day for up to 8 weeks.
    • Children 5 years of age and older weighing 15 to 39 kg: 20 mg once a day for up to 8 weeks.
    • Children younger than 5 years of age: Use and dose must be determined by your doctor.
  • For Zollinger-Ellison Syndrome:
    • Adults: at first, 40 milligrams (mg) 2 times a day. Your doctor may increase your dose as needed.
    • Children: Use and dose must be determined by your doctor.

Side effect

Common Side Effects of Pantoprazole:

  • Abdominal discomfort
  • Diarrhea
  • Dizziness
  • Drowsiness
  • Headache
  • Insomnia or sleep problems
  • Nausea

Serious side effects of Protonix include:

  • Irregular heartbeat
  • Joint pain
  • Muscle spasm
  • Seizures
  • Persistent diarrhea
  • Stomach pain
  • Blood or mucus in the stool and fever

Form and strength

Protonix and its generic alternative Pantoprazole are available in the following form and strengths:

Protonix: Delayed Release Tablet

  • 20 mg
  • 40 mg

Pantoprazole: Delayed Release Tablet (Enteric Coated)

  • 20 mg
  • 40 mg


  • Tell your doctor if you experience any signs of kidney problems while taking Pantoprazole, such as urinating less than usual or having blood in your urine.
  • If you are taking Protonix for an extended period, your body may have difficulty absorbing vitamin B-12, leading to a deficiency of this vitamin. It is important to speak to your doctor.
  • All people taking PPIs such as Protonix may develop certain types of lupus erythematosus or may have worsening of the lupus they already have. Therefore, people suffering from lupus should be extremely cautious while taking Protonix.
  • Pantoprazole may cause thinning of the bones (osteoporosis) or slowed growth in children if taken for an extended period. If you experience any bone pain or have a heightened risk of developing osteoporosis, it is important to inform your doctor.
  • Taking Pantoprazole (Protonix) can rarely result in severe skin reactions such as Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). These reactions can be life-threatening, so if you experience flu-like symptoms or a painful rash, it is important to seek medical help immediately.

Frequently Asked Questions (FAQ)

How should Protonix be taken?

Protonix should be taken exactly as prescribed by your doctor. The typical dose is one 40 mg tablet daily taken with a full glass of water.

How long should I take pantoprazole (Protonix)?

You can take pantoprazole (Protonix) for up to 8 weeks for GERD. But your healthcare provider might extend your treatment depending on the cause of your condition.

What should I do if I miss a dose of Protonix?

If you miss a dose of Protonix, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at once.

Is it safe to take Protonix for a long period of time?

In general, Protonix is safe to take for an extended period. However, it is important to talk to your doctor about any potential risks or side effects before taking Protonix.


It's important to purchase Protonix from verified Canadian pharmacy.

Additional information

Generic name:



Delayed Release Tablet, Delayed Release Tablet (Enteric Coated)


20mg, 40mg

Quantities Available:

90, 100