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Movantik (Naloxegol) Shopper Approved

Prescription Prescription Required FormationFormulation: Tablet

Movantik

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Prescription Prescription Required FormationFormulation: Tablet

Naloxegol

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Movantik (active ingredient: naloxegol) is a prescription medication used to treat opioid-induced constipation (OIC) in adults with chronic non-cancer pain who are taking opioid pain medications regularly.

Opioids can slow movement in the digestive tract, making bowel movements harder or less frequent. Movantik helps relieve constipation caused by opioids without directly treating pain.

Opioid-Induced Constipation

Movantik is used for adults who develop constipation because of ongoing opioid use. Opioid-induced constipation may cause symptoms such as:

  • Fewer bowel movements than usual
  • Hard or dry stools
  • Straining during bowel movements
  • Bloating or abdominal discomfort
  • A feeling that the bowel has not fully emptied

Movantik is specifically used when constipation is related to opioid medication use.

How Movantik Works

Movantik belongs to a class of medications called peripherally acting mu-opioid receptor antagonists, also known as PAMORAs.

It works by blocking the effects of opioids on opioid receptors in the gastrointestinal tract. This helps restore normal bowel movement activity and reduce constipation.

Because Movantik mainly works outside the brain and spinal cord, it is designed to relieve constipation without reducing the pain-relieving effects of opioid medications.

Movantik is used when opioid medications cause constipation by slowing movement in the digestive tract. It may help improve bowel movement frequency, reduce straining, and relieve constipation related to ongoing opioid use.

Movantik is not a general laxative for all types of constipation. It is specifically used for constipation caused by opioid medications.

Recommended Dosage

The usual recommended dose of Movantik is 25 mg by mouth once daily.

It should be taken in the morning on an empty stomach, at least 1 hour before the first meal of the day or 2 hours after a meal.

Lower Starting Dose

Some people may need to start with a lower dose of 12.5 mg once daily, especially if they have reduced kidney function or cannot tolerate the 25 mg dose.

For adults with moderate, severe, or end-stage kidney impairment, the recommended starting dose is 12.5 mg once daily. If this dose is well tolerated but constipation symptoms continue, the healthcare provider may increase the dose to 25 mg once daily.

Important Dosing Instructions

Swallow the tablet whole with water. Do not take more than one dose per day unless directed by your healthcare provider.

Before starting Movantik, your healthcare provider may recommend stopping other maintenance laxatives. If constipation symptoms continue after 3 days of Movantik treatment, your provider may tell you to restart laxatives.

If opioid pain medication is stopped, Movantik should usually also be stopped, because it is intended to treat constipation caused by opioids.

Common Side Effects of Movantik (naloxegol):

  • Stomach or abdominal pain
  • Diarrhea
  • Nausea
  • Gas or bloating
  • Vomiting
  • Headache
  • Increased sweating

Serious Side Effects of Movantik (naloxegol):

  • Severe or worsening abdominal pain
  • Severe diarrhea
  • Signs of dehydration
  • Severe dizziness
  • Fainting
  • Symptoms that feel like opioid withdrawal:
    • Sweating
    • Chills
    • Diarrhea
    • Stomach pain
    • Anxiety
    • Irritability
    • Yawning

Movantik (naloxegol) is available in the following forms and strengths:

Movantik: Tablet

  • 12.5 mg
  • 25 mg

Before taking Movantik, tell your healthcare provider about your medical history, allergies, and all medications or supplements you are taking. Movantik can interact with certain medications and may not be safe for people with specific stomach, intestinal, kidney, or liver conditions.

Bowel Obstruction

Do not take Movantik if you have a known or suspected bowel obstruction or if you are at risk for repeated bowel obstruction. Movantik can increase movement in the intestines, which may be dangerous if there is a blockage.

Stomach or Intestinal Problems

Movantik may increase the risk of serious gastrointestinal problems, including severe abdominal pain or, rarely, a tear in the stomach or intestinal wall. Tell your healthcare provider if you have conditions that may weaken the stomach or intestinal wall, such as inflammatory bowel disease, diverticulitis, stomach or intestinal cancer, or recent gastrointestinal surgery.

Seek medical help right away if you develop severe, persistent, or worsening abdominal pain.

Opioid Withdrawal Symptoms

Movantik may cause symptoms of opioid withdrawal in some people. Symptoms may include sweating, chills, diarrhea, stomach pain, anxiety, irritability, or yawning. Contact your healthcare provider if these symptoms occur while taking Movantik.

Drug Interactions

Do not take Movantik with strong CYP3A4 inhibitors, such as certain antifungal or antibiotic medications, because they can greatly increase naloxegol levels and raise the risk of side effects. Movantik may also interact with other medications that affect CYP3A4, so your healthcare provider should review all medications, vitamins, and supplements you take before starting treatment.

Kidney or Liver Problems

Tell your healthcare provider if you have kidney or liver disease before taking Movantik. People with reduced kidney function may need a lower starting dose. Movantik is generally not recommended in people with severe liver impairment.

Pregnancy and Breastfeeding

If you are pregnant, planning to become pregnant, or breastfeeding, talk to your healthcare provider before taking Movantik. Your provider can help weigh the potential benefits and risks and decide whether Movantik is appropriate for your situation.

Important Reminder

Take Movantik exactly as prescribed. Do not take more than directed, and do not use it for constipation that is not caused by opioid medication unless your healthcare provider tells you to do so.

What is Movantik used for?

Movantik is used to treat opioid-induced constipation (OIC) in adults with chronic non-cancer pain. It is used when opioid pain medications slow bowel movement activity and cause constipation.

How does Movantik work?

Movantik belongs to a class of medications called peripherally acting mu-opioid receptor antagonists (PAMORAs). It works mainly in the digestive tract by blocking opioid effects on the gut. This helps improve bowel movement activity without directly blocking the pain-relieving effects of opioids in the brain.

How should I take Movantik?

Movantik is taken by mouth, usually once daily in the morning. It should be taken on an empty stomach, at least 1 hour before the first meal of the day or 2 hours after a meal.

What is the usual dose of Movantik?

The usual recommended dose is 25 mg once daily. Some people, such as those with reduced kidney function or those who do not tolerate the higher dose, may be started on 12.5 mg once daily. Your healthcare provider will determine the dose that is safest and most appropriate for you.

Can Movantik be taken with laxatives?

Your healthcare provider may ask you to stop other maintenance laxatives before starting Movantik. If constipation does not improve after a few days, your provider may tell you whether to restart or add a laxative.

What are common side effects of Movantik?

Common side effects may include abdominal pain, diarrhea, nausea, gas, vomiting, headache, and increased sweating. Contact your healthcare provider if side effects are severe, persistent, or bothersome.

Can Movantik cause opioid withdrawal symptoms?

Yes. Movantik may cause opioid withdrawal symptoms in some people. These may include sweating, chills, diarrhea, stomach pain, anxiety, irritability, or yawning. Contact your healthcare provider if you notice these symptoms while taking Movantik.

Who should not take Movantik?

Do not take Movantik if you have a known or suspected bowel obstruction or are at risk for repeated bowel obstruction. Movantik should also not be taken with certain strong medications that affect CYP3A4 enzymes, because they can increase naloxegol levels and raise the risk of serious side effects.

Can I take Movantik if I stop taking opioids?

If you stop taking opioid pain medication, Movantik should usually be stopped as well. Movantik is specifically used to treat constipation caused by opioids.

Is Movantik a general laxative?

No. Movantik is not used for all types of constipation. It is specifically prescribed for constipation caused by opioid medications in eligible adults.

Can Movantik be used during pregnancy or breastfeeding?

If you are pregnant, planning to become pregnant, or breastfeeding, talk to your healthcare provider before taking Movantik. Your provider can help weigh the potential benefits and risks and decide whether it is appropriate for your situation.

REVIEWS

Additional Information Book
Generic name:

Naloxegol

Formulation:

Tablet

Strength(s):

12.5mg, 25mg

Quantities Available:

30

Why customers love Online Pharmacies Canada

Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.

Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.

How to Order

How much Movantik can I order at once from a Canadian pharmacy?

When ordering Movantik (naloxegol) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.

Here’s what you need to know:

Dosage and Quantity: Movantik is commonly prescribed in a dosages of 12.5 mg or 25 mg taken once daily. For a 90-day supply, this means you would order 90 tablets (90 days x 1 tablet per day).

Do you sell naloxegol?

No, we don’t sell naloxegol specifically, but you can still enjoy competitive prices on Movantik, which contains naloxegol as an active ingredient. However, to purchase Movantik, you will need a valid prescription from your healthcare provider. We require this to dispense the medication safely and appropriately. You can provide your prescription by mailing, faxing, or uploading it through your online account.

Do you offer shipping of Movantik (naloxegol) to the United States?

Yes, we ship Movantik (naloxegol) to both the United States and Puerto Rico.

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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Movantik (Naloxegol). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Movantik (Naloxegol).