Indications
Salofalk is a prescription medication used to treat inflammatory bowel disease (IBD), such as ulcerative colitis. It can be used to treat inflammation of the lining of the large bowel and rectum (acute ulcerative colitis).
Salofalk contains mesalamine, also known as 5-aminosalicylic acid (5-ASA). It belongs to the group of medications known as anti-inflammatories. It works by blocking certain chemicals in the body that cause inflammation, which helps to reduce the symptoms of inflammatory bowel disease such as ulcerative colitis and Crohn's disease.
Use and Dosage
Salofalk tablets should be taken in the morning, at midday and in the evening, 1 hour before meals. They should be swallowed whole, not chewed. Follow your doctor's instructions regarding the dosage and timing of the tablets. You should also consult the medication leaflet or your doctor for more specific instructions on how to use Salofalk tablets.
The recommended dosage of Salofalk varies depending on the type and severity of the condition being treated. For the treatment of acute episodes of ulcerative colitis, a dose of 1.5g to 3.0g mesalazine in three divided doses (1 or 2 tablets of Salofalk 500mg three times daily) may be used. For maintenance therapy, the usual dose is lower, typically starting at 1.5g per day and reducing to 0.75g per day. However, follow your doctor's specific instructions and consult the medication leaflet for further information on how to use Salofalk.
If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Side Effects
Common Side Effects of Salofalk (Mesalazine):
- Abdominal or stomach cramps or pain (mild)
- Acne
- Back pain
- Bloating
- Blood pressure changes
- Changed sense of touch
- Constipation
- Decreased sperm count
- Diarrhea (mild)
- Dizziness
- Ear or throat pain
- Fatigue
- Gas
- Hair loss
- Headache (mild)
- Increased sensitivity of the skin to sunlight
- Increased urge to have a bowel movement
- Irritation of the rectal area
- Muscle or joint pain
- Nausea
- Tiredness
- Tremor
- Vomiting
- Weakness
Serious Side Effects of Salofalk (Mesalazine):
- Blood in the urine
- Burning pain or discomfort around the anus
- Chest pain
- Chills
- Cough
- Dark urine
- Decreased urine production
- Dizziness
- Fast or pounding heartbeat
- Fever
- Headache
- Increased urination at night
- Listlessness
- Loss of appetite
- Nausea
- Pale skin
- Pale stools
- Prolonged dizziness
- Sensation of numbness or tingling in the hands and feet
- Severe diarrhea
- Severe headache
- Severe stomach pain
- Shortness of breath
- Skin rash and itching
- Stiff neck
- Symptoms may include fever or chills
- Unusual bruising or bleeding
- Unusual tiredness or weakness
- Vision changes
- Vomiting
- Weight loss
- Wheezing
- Worsening symptoms
- Yellowing of the skin or whites of the eyes
Forms and Strength
Salofalk (Mesalazine) is available in the following forms and strength:
Salofalk: EC Tablet (DR)
- 500 mg
Cautions
- Hypersensitivity: Salofalk should not be used in patients who have a hypersensitivity (allergic) reaction to any of its ingredients.
- Liver or kidney problems: Salofalk should be used with caution in patients with liver or kidney problems, as their condition could be worsened with the use of Salofalk.
- Heart problems: Patients with a history of heart problems such as heart failure or heart disease should be closely monitored, as Salofalk could exacerbate these conditions.
- Blood problems: Salofalk should also be used with caution in patients with a history of blood problems, such as anemia or low white blood cell count, as it can affect blood cell counts.
- Pregnancy and breastfeeding: The use of Salofalk during pregnancy and breastfeeding should be discussed with a doctor as it may not be safe for the baby.
- Interactions with other drugs: Salofalk may interact with other medications, including non-steroidal anti-inflammatory drugs (NSAIDs) and blood thinners, and should be used with caution in patients taking these drugs.
- Possible allergic reactions: Patients should monitor for signs of allergic reaction, such as rash or swelling, while taking Salofalk.
- Monitoring for side effects: Patients should be monitored for potential side effects of Salofalk, which can include nausea, diarrhea, and headache.
Frequently Asked Questions (FAQ)
Can Salofalk be used during pregnancy and breastfeeding?
The use of Salofalk during pregnancy and breastfeeding should be discussed with a doctor as it may not be safe for the baby.
How long does it take for Salofalk (Mesalazine) to work?
The amount of time it takes for Salofalk (Mesalazine) to work can vary depending on the individual patient and their specific condition. Some patients may see improvement within a few days, while others may take several weeks before they notice a difference.
Is it possible to overdose on Salofalk (Mesalazine)?
Overdosing on Salofalk can cause symptoms such as confusion, dizziness, fever, and rapid heartbeat. Patients who suspect they have overdosed on Salofalk tablet should seek emergency medical attention immediately.
Can Salofalk (Mesalazine) be taken with food?
Salofalk can be taken with or without food. However, patients should follow the dosing instructions provided by their doctor or pharmacist to ensure that they are taking the medication correctly.
Resources
- https://www.myvmc.com/drugs/salofalk-tablets/
- https://www.medbroadcast.com/drug/getdrug/salofalkj
- https://www.abbvie.ca/content/dam/abbvie-dotcom/ca/en/documents/products/SALOFALK_TABLETS_PI_EN.pdf
- https://www.mims.com/hongkong/drug/info/salofalk?type=full
- https://www.everydayhealth.com/ulcerative-colitis/guide/
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