Indications
Diclectin is a drug used to treat nausea and vomiting in pregnancy, which is a common condition affecting 50%-90% of pregnant women. It contains two medications, doxylamine succinate and pyridoxine hydrochloride, that work on the centers in the brain that control these symptoms.
Doxylamine workS by blocking histamine receptors in the brain that control nausea and vomiting. Pyridoxine, also known as vitamin B6, is thought to help alleviate symptoms of nausea and vomiting by reducing levels of certain neurotransmitters in the brain. The combination of these two medications is believed to work together to effectively alleviate symptoms of nausea and vomiting in pregnant women.
Use and Dosage
Diclectin is available in a delayed-release tablet form to take by mouth usually 2 tablets at bedtime. If nausea and vomiting persist during the day or your symptoms are severe, your doctor may advise including one tablet in the morning and one tablet in the mid-afternoon. The tablets should be swallowed whole and not crushed or split.
The recommended dose is two tablets at bedtime, and in severe cases or if nausea or vomiting occurs during the day, the doctor may prescribe additional doses. However, the maximum recommended dose is four tablets per day, and patients should not exceed this limit unless directed to do so by their doctor.
Take a Diclectin tablet exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Side Effects
Common Side Effects of Diclectin (Doxylamine/Pyridoxine Hcl):
- Anxiety nightmares
- Bloating
- Blurred vision
- Constipation
- Diarrhea
- Difficulty urinating
- Dizziness
- Drowsiness
- Fast heart rate vertigo
- Fatigue
- Headache
- Irritability
- Itching
- Malaise
- Numbness and tingling
- Palpitations
- Rash
- Shortness of breath
- Sleepiness
- Stomach upset
- Trouble sleeping (insomnia)
Serious Side Effects of Diclectin (Doxylamine/Pyridoxine Hcl):
- Difficulty breathing
- Drowsiness
- Hives
- Swelling of the face lips tongue or throat
Forms and Strength
Diclectin (Doxylamine/Pyridoxine Hcl) is available in the following forms and strength:
Diclectin: Tablet
- 10mg/10mg
Doxylamine/Pyridoxine Hcl: Tablet
- 10mg/10mg
Cautions
- Diclectin has anticholinergic properties and should be used with caution in women with asthma, increased intraocular pressure, narrow-angle glaucoma, or other conditions affected by anticholinergic activity.
- Diclectin is a prescription medication, so it should only be used under the guidance of a healthcare professional.
- Like all medications, Diclectin may cause side effects. The specific list of side effects and other serious side effects or health problems that may occur with Diclectin can be found in the product monograph or by consulting a healthcare professional.
- Diclectin is not clear whether Diclectin is safe for use during pregnancy or breastfeeding. Women who are pregnant or breastfeeding should consult their healthcare professional before taking this medication.
- Diclectin should not be used in women who have a hypersensitivity or allergy to doxylamine, pyridoxine or any of the other ingredients in the medication.
- Diclectin may cause drowsiness or impairment, so individuals who take Diclectin should be cautious when operating heavy machinery, driving, or performing other tasks that require alertness and coordination.
- Diclectin may interact with other medications, so individuals who are taking any other prescription or over-the-counter medications should check with their healthcare provider before taking Diclectin.
- Diclectin is not known whether Diclectin passes into breast milk, so individuals who are breastfeeding should consult their healthcare provider before taking this medication.
- Diclectin should be stored at room temperature and kept out of the reach of children.
Frequently Asked Questions (FAQ)
Can Diclectin be used if I am breastfeeding?
Consult with a healthcare provider before taking Diclectin if you are breastfeeding, as it is not known whether the medication passes into breast milk.
What should I do if I miss a dose of Diclectin?
If you miss a dose of Diclectin, take it as soon as you remember. However, if it is close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.
Can Diclectin interact with any other medications?
Diclectin may interact with other medications, so individuals who are taking any other prescription or over-the-counter medications should check with their healthcare provider before taking Diclectin.
Can Diclectin be crushed or split?
Diclectin should not be crushed or split, as it is a delayed-release tablet designed to be taken whole.
How long does it take for Diclectin to start working?
The onset of action for Diclectin is approximately one hour.
Can I take Diclectin with food?
Diclectin can be taken with or without food.
Resources
- https://www.rxlist.com/doxylamine-pyridoxine/generic-drug.htm
- https://mothertobaby.org/fact-sheets/doxylamine-succinate-pyridoxine-hydrochloride-diclegisdiclectin-pregnancy/
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/021876s002lbl.pdf
- https://www.medbroadcast.com/drug/getdrug/diclectin
- https://www.accessdata.fda.gov/drugsatfda_docs/nda/2016/209661Orig1s000ClinPharmR.pdf
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