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Prednisolone

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Prednisolone

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Prednisolone is a prescription corticosteroid used to reduce inflammation and control an overactive immune response. It is similar to cortisol, a natural hormone produced by your adrenal glands.

Your healthcare provider may prescribe prednisolone for many different conditions because inflammation and immune-system activity can affect almost any part of the body. The dose, form, and length of treatment will depend on the condition being treated and how you respond.

Allergic reactions

Prednisolone may be used to control severe allergic reactions when standard allergy treatments are not enough. It helps reduce swelling, redness, itching, and inflammation caused by an excessive immune response.

Your healthcare provider may prescribe it for conditions such as severe asthma attacks, serious medication allergies, or severe allergic inflammation affecting the skin, nose, or airways.

Prednisolone does not usually replace emergency treatment for a life-threatening allergic reaction. Severe symptoms such as difficulty breathing, throat swelling, or fainting require immediate medical attention.

Autoimmune diseases

An autoimmune disease develops when the immune system mistakenly attacks healthy cells and tissues. Prednisolone lowers immune-system activity and may help prevent or reduce this damage.

It may be used to manage conditions such as rheumatoid arthritis, lupus, and certain forms of multiple sclerosis. By reducing immune activity, prednisolone can help relieve swelling, stiffness, pain, and other symptoms during a flare-up.

Prednisolone may control symptoms, but it does not cure most autoimmune diseases. It is often used with other medications as part of a long-term treatment plan.

Inflammatory conditions

Prednisolone can reduce inflammation in many organs and tissues. It may be prescribed for inflammatory bowel disease, including Crohn’s disease and ulcerative colitis.

In these conditions, inflammation in the digestive tract can cause abdominal pain, diarrhea, rectal bleeding, and weight loss. Prednisolone may be used for a limited period to bring a flare-up under control.

It may also be prescribed for severe inflammatory skin conditions, such as psoriasis or eczema, when other treatments have not provided enough relief.

Endocrine and adrenal disorders

Your adrenal glands normally produce cortisol, a hormone that helps your body respond to stress, control inflammation, maintain blood pressure, and regulate metabolism.

People with adrenal insufficiency do not produce enough natural corticosteroid hormones. Prednisolone may sometimes be used as replacement treatment to provide the steroid hormone the body needs.

Depending on the type of adrenal insufficiency, another medication may also be needed to replace other hormones normally produced by the adrenal glands.

Blood disorders

Prednisolone may be used for certain conditions that affect blood cells.

For example, it may be prescribed for immune thrombocytopenia, a condition in which the immune system destroys platelets. Platelets help the blood clot, so a low platelet count can lead to easy bruising or bleeding.

Prednisolone may also be used for autoimmune hemolytic anemia, in which the immune system destroys red blood cells too quickly. Reducing immune activity can help slow the destruction of these cells.

Eye conditions

Prednisolone may be prescribed for severe inflammation affecting the eyes or nearby tissues. Examples include uveitis, which causes inflammation inside the eye, and optic neuritis, which affects the nerve that connects the eye to the brain.

Eye inflammation can cause pain, redness, blurred vision, sensitivity to light, or reduced vision. Prompt treatment may help prevent permanent eye damage.

The form of prednisolone used depends on the condition. Treatment may include tablets, liquid, injections, or eye drops. Oral prednisolone should only be used for an eye condition when prescribed and monitored by an appropriate healthcare professional.

Other possible uses

Prednisolone may also be used for certain respiratory, kidney, skin, neurological, rheumatic, and blood-related disorders. In some cases, it may form part of treatment for specific cancers or help manage complications related to cancer treatment.

The approved uses may vary according to the product, dosage form, and country. Prednisolone has strong anti-inflammatory effects and changes how the immune system responds to different triggers.

How prednisolone works

Inflammation is part of the body’s normal response to injury, infection, or irritation. However, excessive or long-lasting inflammation can damage healthy tissue and cause symptoms such as pain, redness, swelling, stiffness, and breathing problems.

Prednisolone reduces the production and activity of substances that cause inflammation. It also lowers the activity of immune cells that contribute to allergic and autoimmune reactions.

As inflammation decreases, symptoms such as pain, swelling, itching, stiffness, and breathing difficulty may improve. Prednisolone controls the inflammatory response, but it may not treat the underlying cause of every condition.

What results can you expect?

Prednisolone often begins working within a few hours, but the time needed to notice an improvement depends on your condition, dose, and response to treatment.

Some people may notice relief within a day. Other conditions may require several days or longer before symptoms improve.

Continue taking prednisolone exactly as prescribed, even if you begin to feel better. Do not take more than directed or stop treatment suddenly without speaking with your healthcare provider.

Important treatment considerations

The risk of side effects generally increases with higher doses and longer treatment periods. Your healthcare provider will usually aim to prescribe the lowest effective dose for the shortest appropriate time.

Long-term prednisolone treatment can reduce your body’s natural production of cortisol. For this reason, your dose may need to be gradually reduced rather than stopped suddenly.

Prednisolone also lowers immune-system activity and may make it harder for your body to fight infections. Contact your healthcare provider if you develop fever, chills, a persistent sore throat, or other signs of infection during treatment.

Take prednisolone only for the condition and length of time recommended by your healthcare provider. Regular follow-up appointments may be needed to monitor your symptoms, treatment response, and possible side effects.

Prednisolone is available as a tablet that you take by mouth. Tablets come in different strengths, including 5 mg. Check the label carefully so that you know how many tablets to take for each dose.

Take prednisolone exactly as directed by your healthcare provider. Your dose, dosing schedule, and length of treatment will depend on the condition being treated and how your body responds to the medication.

How to take prednisolone

Take prednisolone with food or milk to help reduce stomach irritation. Swallow the tablet with water.

Prednisolone is often taken in the morning because this is closer to the time when your body naturally produces corticosteroid hormones. Taking it earlier in the day may also reduce sleep problems. However, follow the specific schedule provided by your healthcare provider.

Depending on your condition, you may be instructed to take prednisolone:

  • Once a day
  • Several times throughout the day
  • As one larger daily dose
  • Every other day

Do not change the timing or frequency of your doses unless your healthcare provider tells you to do so.

Prednisolone dosage for adults

The usual initial dose for adults can range from 5 mg to 60 mg per day. The total daily dose may be taken at one time or divided into several smaller doses.

The exact dose depends on factors such as:

  • The condition being treated
  • The severity of your symptoms
  • Your age and medical history
  • Your response to treatment
  • Other medications you take
  • Whether you develop side effects

Some conditions may require a higher dose at the beginning of treatment. Your healthcare provider may lower the dose once your symptoms are under control.

Prednisolone dosage for children

A child’s dose is usually based on body weight, age, medical condition, and response to treatment. Children should only take prednisolone under the supervision of a healthcare provider.

Do not give a child an adult dose or use leftover medication from another person. A healthcare provider should calculate and adjust the child’s dose carefully.

Dose adjustments

Your healthcare provider may change your dose during treatment. The dose may be increased if your symptoms are not adequately controlled or temporarily adjusted if your body is under physical stress, such as during a serious infection, injury, or surgery.

The dose may be reduced once your condition improves. Healthcare providers usually aim to prescribe the lowest dose that controls symptoms while limiting side effects.

Do not change your dose on your own, even if you feel better or experience side effects.

Do not stop prednisolone suddenly

If you have taken prednisolone for more than a short period, your body may reduce its natural production of cortisol. Stopping the medication suddenly can leave your body without enough steroid hormone.

Your healthcare provider may gradually reduce your dose over time. This process is called tapering.

Stopping prednisolone too quickly may cause symptoms such as:

  • Severe tiredness
  • Weakness
  • Body aches or joint pain
  • Nausea or vomiting
  • Dizziness
  • Low blood pressure
  • Loss of appetite
  • A return or worsening of the condition being treated

Follow your tapering schedule carefully. Contact your healthcare provider if symptoms return while your dose is being reduced.

What to do if you miss a dose

Take the missed dose when you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule.

Do not take two doses at the same time to make up for a missed dose.

If you take prednisolone on an alternate-day schedule or follow a complex tapering plan, contact your healthcare provider or pharmacist for instructions if you miss a dose.

Tips for remembering your medication

Try to take prednisolone at the same time each day. You may find it helpful to use:

  • A phone alarm
  • A medication reminder application
  • A calendar
  • A pill organizer
  • A written dosing schedule

This can be especially useful when your dose changes during a tapering schedule.

Important dosing reminders

Take only the amount prescribed. Taking more prednisolone than directed or using it for longer than recommended may increase the risk of side effects, including high blood sugar, mood changes, sleep problems, stomach irritation, fluid retention, infection, bone loss, and high blood pressure.

Do not share prednisolone with another person, even if they have similar symptoms.

Contact your healthcare provider or pharmacist if you are unsure about the number of tablets to take, when to take them, how long treatment should continue, or how to follow a tapering schedule.

Common Side Effects of Prednisolone

  • Acne
  • Changes in personality
  • Changes in the way fat is spread around the body
  • Difficulty falling asleep or staying asleep
  • Extreme changes in mood, including unusual happiness
  • Headache
  • Increased appetite
  • Increased sweating
  • Irregular or absent menstrual periods
  • Nausea
  • Slowed healing of cuts and bruises
  • Thin, fragile skin
  • Thinning hair

Serious Side Effects of Prednisolone

  • Depression
  • Difficulty breathing or swallowing
  • Loss of contact with reality
  • Muscle weakness
  • Seizures
  • Stomach swelling
  • Sudden weight gain
  • Swelling of on any part of the body
  • Vision problems

Prednisolone is available in the following forms and strengths:

Prednisolone: Tablet

  • 5 mg

Missed Dose

Take the missed dose as soon as you remember. However, if it is almost time for your next dose or you do not remember until the following day, skip the missed dose and continue with your regular schedule.

Do not take two doses at the same time. Taking extra prednisolone may increase your risk of side effects.

The instructions may be different if you take prednisolone several times a day, every other day, or as part of a tapering schedule. Contact your healthcare provider or pharmacist if you are unsure what to do.

Risk of side effects

Prednisolone can cause side effects, especially when it is taken at a high dose or used for several weeks or longer. In general, the risk increases with higher doses and longer treatment. However, side effects can occur at any dose.

Possible side effects include increased appetite, weight gain, indigestion, trouble sleeping, mood changes, fluid retention, high blood pressure, increased blood sugar, weaker bones, and a greater risk of infection.

Contact your healthcare provider if a side effect is severe, does not improve, or affects your daily activities. Seek prompt medical attention if you develop signs of infection, serious mood or behaviour changes, vision problems, black stools, vomiting blood, or severe muscle weakness.

Do not stop prednisolone suddenly

Do not stop taking prednisolone suddenly unless your healthcare provider tells you to do so. This is especially important if you have taken it for several weeks or have been using a high dose.

Prednisolone is similar to cortisol, a natural hormone produced by your adrenal glands. When you take prednisolone for a long time, your body may reduce its own cortisol production. Stopping treatment suddenly may leave your body without enough cortisol.

Sudden withdrawal may cause severe tiredness, weakness, dizziness, nausea, loss of appetite, body aches, joint pain, or low blood pressure. The condition being treated may also return or become worse.

Your healthcare provider may slowly reduce your dose over several days or weeks. This is called tapering. Follow the tapering schedule carefully, even if you feel well. Contact your healthcare provider if your symptoms return or you feel unwell while your dose is being reduced.

Prednisolone during pregnancy

Tell your healthcare provider if you are pregnant, think you may be pregnant, or plan to become pregnant. Prednisolone may be used during pregnancy when treatment is necessary.

Some studies have suggested possible risks with use during early pregnancy or with prolonged treatment, including possible effects on the baby’s growth. However, untreated inflammation or autoimmune disease may also create risks for you and your baby.

Your healthcare provider will consider your condition, dose, and length of treatment before recommending prednisolone. They may use the lowest effective dose and monitor you and your baby more closely.

Do not suddenly stop taking prednisolone if you become pregnant. Contact your healthcare provider so your treatment can be reviewed safely.

Vaccinations while taking prednisolone

Speak with your healthcare provider before receiving any vaccine while taking prednisolone. High doses or long-term treatment can weaken your immune response.

Live vaccines may not be suitable when your immune system is significantly suppressed. These vaccines contain weakened forms of viruses or bacteria. Examples include some measles, mumps, and rubella vaccines, the chickenpox vaccine, the nasal-spray flu vaccine, and the yellow fever vaccine.

Non-live vaccines cannot cause the infection they are designed to prevent. However, they may not work as well while you are taking an immunosuppressive dose of prednisolone.

Tell the person giving you the vaccine that you are taking prednisolone. Provide your current dose and treatment schedule. Do not receive, delay, or avoid a recommended vaccine without first speaking with your healthcare provider.

Also tell your healthcare provider if you recently received a vaccine or have been in close contact with someone who received a live vaccine.

How long should I take prednisolone?

The length of treatment depends on your condition, the dose, and how well you respond. Some people only need prednisolone for a few days or up to one week. Others may need it for several weeks, months, or longer to control a chronic condition. There is no single maximum length of treatment that applies to everyone. Your healthcare provider will regularly review whether you still need prednisolone and will usually aim to use the lowest effective dose for the shortest appropriate time. Do not continue prednisolone longer than prescribed. If you have taken it for more than a short period, do not stop suddenly. Your healthcare provider may need to reduce your dose gradually to prevent withdrawal symptoms and allow your body to restart its natural cortisol production.

What foods should I avoid while taking prednisolone?

You do not usually need to completely avoid carbohydrates while taking prednisolone. However, prednisolone can increase your appetite, cause fluid retention, and raise your blood sugar, particularly when used at a high dose or for a long time. Try to limit foods and drinks that are high in added sugar, salt, or saturated fat. Examples include candy, cakes, cookies, sugary drinks, chips, and heavily processed foods. Choose balanced meals that include vegetables, fruit, whole grains, lean protein, and appropriate portions of carbohydrate-rich foods. If you have diabetes or develop increased thirst, frequent urination, blurred vision, or unusual tiredness, contact your healthcare provider. You may need blood sugar monitoring or changes to your diabetes treatment while taking prednisolone.

How quickly does prednisolone work?

Prednisolone may begin reducing inflammation within hours, but you may not notice an improvement immediately. Many people notice some benefit within a few days. The exact time depends on the condition being treated, the dose, and your individual response. Some inflammatory conditions may improve quickly, while others may take several days or weeks to respond fully. Continue taking prednisolone exactly as prescribed. Contact your healthcare provider if your symptoms do not improve, become worse, or return while your dose is being reduced.

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Additional Information Book
Generic name:

Prednisolone

Formulation:

Tablet

Strength(s):

5mg

Quantities Available:

28, 84

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Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.

How to Order

How much Prednisolone can I order at once from a Canadian pharmacy?

When ordering Prednisolone from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is standard practice for prescription medications to ensure effective management of chronic conditions without the need for frequent refills.

Here’s what you need to know:

Dosage and Quantity: Prednisolone comes in various dosages depending on your prescription. For example, if you are prescribed 5 mg tablets and instructed to take 4 tablets daily, you would need 360 tablets for a 90-day supply (4 tablets x 90 days).

Do you sell prednisolone?

Yes, we sell prednisolone on our website, and you can enjoy low prices. To purchase prednisolone, you will need a valid prescription from your healthcare provider. We require this to dispense the medication. You can conveniently submit your prescription by mail, fax, or upload it through your online account to facilitate the ordering process.

Do you offer shipping of Prednisolone (prednisolone) to the United States?

Yes, we ship Prednisolone (prednisolone) to both the United States and Puerto Rico.

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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Prednisolone (Prednisolone). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Prednisolone (Prednisolone).