Neo-Synalar Cream (Neomycin Sulfate/Fluocinolone Acetonide)

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Neo-Synalar Cream Brand
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Neomycin Sulfate/Fluocinolone Acetonide (Generic alternate to Neo-Synalar Cream) Generic

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Table of contents:

Neo-Synalar Cream is a prescription medication indicated for the treatment of inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses where secondary bacterial infection is present or likely to occur. It can be used for the treatment of certain skin infections and dermatoses with secondary infection.

The cream contains two active ingredients, neomycin sulfate and fluocinolone acetonide. Neomycin sulfate is an antibiotic that helps to treat or prevent bacterial infections, while fluocinolone acetonide is a corticosteroid that helps to reduce inflammation and itching.

Use and Dosage

Neo-Synalar Cream is intended for use on the skin only. To use Neo-Synalar cream, you should follow the instructions provided by your doctor or pharmacist. Typically, the cream is applied thinly to the affected area of the skin and rubbed in gently.

Use Neo-Synalar Cream exactly as prescribed by your healthcare provider. Do not use more or less of it or use it more frequently than recommended. Also, avoid using Neo-Synalar cream on the face, groin, or underarms, or if you have an allergy to neomycin or fluocinolone acetonide. If you have any questions about the use of Neo-Synalar cream, consult your doctor or pharmacist for more information.

Do not use the cream over a large area of the body or for longer than 1 week without consulting a doctor. Avoid getting the cream in the eyes, nose, or mouth, and if this occurs, promptly wipe off the medication and rinse with water. Use the cream regularly at the same time each day to derive maximum benefit from it.

Side Effects

Common Side Effects of Neo-Synalar Cream (Neomycin Sulfate/Fluocinolone Acetonide):

  • “Hair bumps”
  • Abnormal hair growth
  • Acne
  • Allergic contact dermatitis
  • Burning
  • Dry skin
  • Irritation
  • Itching
  • Rash around the mouth
  • Secondary infection
  • Skin discoloration
  • Stretch marks
  • Thinning and breakdown of the skin

Serious Side Effects of Neo-Synalar Cream (Neomycin Sulfate/Fluocinolone Acetonide):

  • Loss of skin color
  • Red rash around your mouth
  • Stretch marks
  • Heat rash
  • Ear damage
  • Kidney damage

Forms and Strength

Neo-Synalar Cream (Neomycin Sulfate/Fluocinolone Acetonide) is available in the following forms and strength:

Neo-Synalar Cream: Cream

  • 0.5/0.025%


  • Avoid contact with the eyes and mouth when applying Neo-Synalar Cream. If contact occurs, rinse thoroughly with cool water.
  • Avoid prolonged use of Neo-Synalar Cream, as this can increase your risk of developing systemic side effects. Your healthcare provider will monitor you for any signs of systemic side effects.
  • Do not cover the treated area with a bandage or other type of dressing, unless directed to do so by your healthcare provider.
  • Do not use Neo-Synalar Cream if you are allergic to neomycin or fluocinolone acetonide.
  • Do not use the cream on your face, underarms, groin, or diaper area, unless directed to do so by your healthcare provider.
  • Do not use this cream on open wounds or burns.
  • Excessive use or overapplication of the cream can lead to skin irritation or dermatitis.
  • If you experience any signs of an allergic reaction, such as hives, difficulty breathing, or swelling of the lips, tongue, or face, seek medical attention immediately.
  • Inform your healthcare provider about any other medications you are currently taking, as they may interact with Neo-Synalar Cream.
  • Inform your healthcare provider if you have a history of certain medical conditions, such as diabetes, osteoporosis, or liver or kidney disease, as these conditions may affect the way your body responds to the medication.
  • Keep Neo-Synalar Cream out of reach of children.
  • Long-term use of this cream can lead to skin thinning, stretch marks, and other side effects.
  • Neo-Synalar Cream may cause interactions with certain medications, inform your healthcare provider of any medications you are currently taking or plan to take in the future.
  • Neo-Synalar Cream should not be used by pregnant or breastfeeding women without first consulting with their healthcare provider.
  • This cream should be used with caution in patients with a history of allergic reactions to any of its components.

Frequently Asked Questions (FAQ)

Can Neo-Synalar Cream be used during pregnancy or breastfeeding?

Neo-Synalar Cream should only be used during pregnancy or breastfeeding if the potential benefits outweigh the potential risks.

Can I use Neo-Synalar cream if I am pregnant or breastfeeding?

Do not use Neo-Synalar cream if you are pregnant or breastfeeding, as it may harm the baby. Talk to your doctor before using the cream if you are pregnant or breastfeeding.

Is Neo-Synalar cream available over the counter?

Neo-Synalar cream is a prescription medication and is not available over the counter. You will need a prescription from your doctor to obtain the medication.


It's important to purchase Neo-Synalar Cream from verified Canadian pharmacy.

Additional information

Generic name:

Neomycin Sulfate/Fluocinolone Acetonide





Quantities Available:



Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Neo-Synalar Cream (Neomycin Sulfate/Fluocinolone Acetonide). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Neo-Synalar Cream (Neomycin Sulfate/Fluocinolone Acetonide).