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Onglyza (active ingredient: saxagliptin) is a prescription medication used to help control blood sugar levels in adults with type 2 diabetes mellitus.
It is usually used together with a healthy diet and regular physical activity as part of an overall diabetes treatment plan.
Onglyza is used to help improve blood sugar control in adults with type 2 diabetes.
Type 2 diabetes develops when the body does not use insulin properly or does not make enough insulin to keep blood sugar levels within a healthy range.
Over time, high blood sugar can increase the risk of complications involving the heart, kidneys, nerves, and eyes.
Onglyza may help lower blood sugar levels, especially after meals.
Onglyza belongs to a group of medications called dipeptidyl peptidase-4 (DPP-4) inhibitors.
It works by increasing the activity of natural hormones called incretins. These hormones are released after you eat and help the body control blood sugar.
When blood sugar levels rise after a meal, incretin hormones help the pancreas release more insulin.
Insulin allows glucose to move from the bloodstream into the body’s cells, where it can be used for energy.
By helping incretin hormones stay active longer, Onglyza can increase insulin release when blood sugar is elevated.
Incretin hormones also help reduce the amount of glucagon released by the pancreas.
Glucagon normally signals the liver to release glucose into the bloodstream. By lowering glucagon activity, Onglyza can help reduce unnecessary glucose production by the liver.
Onglyza is intended to work alongside healthy eating and regular physical activity, not replace them.
Following your recommended diabetes care plan can help improve blood sugar control and support the effectiveness of your medication.
Take Onglyza exactly as prescribed by your healthcare provider.
Your provider may monitor your blood sugar and A1C levels to see how well the medication is working and may adjust your treatment if needed.
Onglyza is available as a tablet taken by mouth once daily.
You can take it with or without food, depending on what is most convenient for you.
Swallow the tablet whole with water. Do not cut, crush, or chew the tablet unless your healthcare provider tells you otherwise.
The usual recommended dose is:
Your healthcare provider will choose the dose that is right for you based on your medical condition, kidney function, response to treatment, and other medications you take.
Try to take Onglyza at approximately the same time every day.
Taking it on a regular schedule can help you remember your dose and maintain steady medication levels in your body.
Onglyza works best when it is used as part of a complete diabetes treatment plan.
This may include:
Continue following the diet and exercise plan recommended by your healthcare provider.
Continue taking Onglyza even if you feel well.
Type 2 diabetes often does not cause noticeable symptoms, even when blood sugar levels are too high.
Do not stop taking Onglyza or change your dose without speaking with your healthcare provider, as this may cause your blood sugar levels to rise.
Some people may need a lower dose of Onglyza.
Your healthcare provider may adjust your dose if you have kidney problems or if you take certain medications that affect how saxagliptin is processed in the body.
Regular blood tests may be needed to monitor your kidney function and blood sugar control.
Do not take more or less Onglyza than prescribed, and do not take it more often than directed.
Taking extra medication will not improve blood sugar control faster and may increase the risk of side effects.
Onglyza (Saxagliptin) is available in the following forms and strength:
Onglyza may increase the risk of heart failure, especially in people who already have heart or kidney problems.
Tell your healthcare provider if you have a history of heart failure. Contact your healthcare provider promptly if you develop symptoms such as shortness of breath, unusual tiredness, swelling of the feet or ankles, or sudden weight gain.
Onglyza does not usually cause low blood sugar when taken by itself. However, the risk of hypoglycemia may increase when Onglyza is taken with insulin or certain diabetes medications, such as sulfonylureas.
Signs of low blood sugar may include:
Your healthcare provider may adjust the dose of your other diabetes medications if needed.
Onglyza has been associated with pancreatitis, which is inflammation of the pancreas.
Stop taking Onglyza and contact your healthcare provider right away if you develop severe and persistent abdominal pain, especially if the pain spreads to your back or is accompanied by vomiting.
Serious allergic reactions can occur with Onglyza.
Seek immediate medical attention if you develop:
Tell your healthcare provider if you have previously had an allergic reaction to saxagliptin or another DPP-4 inhibitor.
Your kidneys help remove saxagliptin from your body.
If you have kidney disease, your healthcare provider may need to use a lower dose of Onglyza and monitor your kidney function during treatment.
Tell your healthcare provider if you have kidney problems before starting Onglyza.
Tell your healthcare provider if you have a history of liver disease before starting Onglyza.
Your provider can determine whether additional monitoring is needed based on your overall health and other medications.
Medications in the DPP-4 inhibitor class have been associated with gallbladder problems in some patients.
Contact your healthcare provider if you develop severe pain in the upper right side of your abdomen, fever, nausea, vomiting, or yellowing of the skin or eyes.
Some people taking DPP-4 inhibitors such as Onglyza have developed severe joint pain.
Contact your healthcare provider if you develop significant or persistent joint pain while taking the medication.
Rarely, DPP-4 inhibitors can cause a serious skin condition called bullous pemphigoid, which causes large, fluid-filled blisters.
Contact your healthcare provider if you develop unexplained blisters, sores, or peeling skin.
If you are pregnant, planning to become pregnant, or think you may be pregnant, tell your healthcare provider before taking Onglyza.
Good blood sugar control is especially important during pregnancy. Your healthcare provider will determine which diabetes treatment is most appropriate for you.
Talk to your healthcare provider before taking Onglyza if you are breastfeeding.
Your provider can help determine whether Onglyza is appropriate or whether another treatment would be preferred.
While taking Onglyza, your healthcare provider may monitor your:
Regular monitoring helps make sure your diabetes treatment remains safe and effective.
Norpramin does not usually work right away. Some people may notice early changes in sleep, energy, or mood within the first several days to a few weeks. However, it can take about 2 to 3 weeks or longer to feel the full benefits. Keep taking Norpramin as prescribed, even if you do not notice an immediate improvement.
Yes. Weight gain can occur with tricyclic antidepressants such as Norpramin, although it does not happen to everyone. Some people may notice little or no change in weight, while others may lose weight. Tell your healthcare provider if you notice a significant or unexpected change in your weight.
Norpramin is not considered addictive in the same way as habit-forming or controlled medications. However, your body can become used to the medication over time. Stopping Norpramin suddenly may cause withdrawal-like symptoms or make your depression symptoms return. If treatment needs to be stopped, your healthcare provider may gradually lower your dose.
It is generally best to avoid or limit alcohol while taking Norpramin. Alcohol can increase side effects such as drowsiness, dizziness, poor coordination, and impaired judgment. Talk to your healthcare provider about whether any amount of alcohol is safe for you while taking Norpramin.
| Generic name: | Saxagliptin |
|---|---|
| Formulation: | Tablet |
| Strength(s): | 2.5mg, 5mg |
| Quantities Available: | 28, 30, 84, 90, 168 |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Onglyza (saxagliptin) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is standard for prescription medications to ensure effective management of chronic conditions without frequent refills.
Here’s what you need to know:
Dosage and Quantity: Onglyza is commonly prescribed in a dosage of 2.5 mg or 5 mg, taken once daily. For a 90-day supply, this means you would order 90 tablets (90 days x 1 tablet per day).
Yes, we sell saxagliptin on our website. You can enjoy low prices when you order through us. To purchase saxagliptin, you will need a valid prescription from your healthcare provider. We require this prescription to dispense the medication safely and appropriately. You have the option to submit your prescription by mailing it to us, faxing it, or uploading it through your online account.
Yes, we ship Onglyza (saxagliptin) to both the United States and Puerto Rico.
Watch how Online Pharmacies Canada is helping customers save money on their medications.
Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Onglyza (Saxagliptin). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Onglyza (Saxagliptin).
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