To take methoxsalen, you should swallow an uncoated tablet with low fat food or milk, as instructed by your doctor. Typically, the tablet is taken 90 minutes to 2 hours before UVA light treatment. Taking methoxsalen with food can help with better absorption of the medication and reduce nausea.
The amount of methoxsalen prescribed depends on your body weight, medical condition, and response to treatment. The UVA light treatment’s duration and frequency depend on your skin type and how you respond to treatment. Typically, you will receive UVA light treatments 2 to 4 times a week initially, and less often as your condition improves.
After taking the medication, you should wear UVA-blocking wrap-around sunglasses during daylight hours for 24 hours, reducing methoxsalen binding to your lenses, which could cause cataracts. During daylight hours, avoid sunlight on your skin or lips for at least 8 hours after taking methoxsalen, as exposure to UVA rays could damage your skin and lead to sunburn. If you cannot avoid sunlight, wear protective clothing or sunscreen that blocks UVA light on the skin, as advised by your doctor or pharmacist. Do not apply sunscreen to areas of your skin affected by psoriasis until after the UVA light treatment.
During the UVA light treatment, you must follow all instructions given by your healthcare provider. After the treatment, avoid sunbathing for 48 hours to avoid severe burns. Please speak to your doctor for more information.
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