Lioresal DS (Baclofen)

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Lioresal DS Brand

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Baclofen (Generic alternate to Lioresal DS) Generic
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Lioresal DS (generically known as Baclofen) is a centrally acting muscle relaxant commonly prescribed to manage severe spasticity (muscle stiffness and tightness) from cerebral or spinal origin in adult and pediatric patients. It belongs to two groups of medications known as muscle relaxants and antispastics. It works by relaxing the muscles.

Baclofen is also used to treat pain and certain types of spasticity from multiple sclerosis, spinal cord injuries, or other spinal cord diseases. It is available in various forms such as tablets and injections by prescription only.

Use and Dosage

Baclofen comes as a tablet to take by mouth usually is taken 3 times a day at evenly spaced intervals. It should be taken orally with or without food as directed by a healthcare provider. Tablets are usually meant to be swallowed whole with water as the medication may have a bitter taste or may irritate the mouth and throat if chewed.

The dosage and frequency of the medication will depend on the individual patient and their medical condition, as determined by their healthcare provider. The usual starting dose for adults is 10 mg (half a tablet), taken three times a day, and the medication may be gradually increased as needed. The maximum recommended dose of Lioresal DS is 20mg taken four times a day. Treatment should be initiated with a low dose, which may be gradually increased over a period of several days or weeks.

Take it exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Side Effects

Common Side Effects of Lioresal DS (Baclofen):

  • Confusion
  • Constipation
  • Difficulty falling asleep or staying asleep
  • Dizziness
  • Frequent urination
  • Headache
  • Nausea
  • Tiredness
  • Weakness

Serious Side Effects of Lioresal DS (Baclofen):

  • Breathing problems
  • Confusion
  • Dark urine
  • Decreased urine production
  • Diarrhea
  • Difficulty speaking
  • Difficulty urinating, bloody or dark urine
  • False sense of well-being
  • Hallucinations (seeing or hearing things that are not there)
  • Loss of appetite
  • Loss of coordination
  • Muscle pain
  • Nightmares or vivid dreams
  • Pale stools
  • Seeing things or hearing voices that do not exist
  • Seizures
  • Skin rash or hives
  • Slow heartbeat
  • Vomiting
  • Weight loss
  • Yellowing of the skin or whites of the eyes

Forms and Strength

Lioresal DS (Baclofen) is available in the following forms and strength:

Baclofen: Tablet

  • 20 mg


  • Since the precise mechanisms of action of Lioresal (baclofen) are not fully known, caution is advised when prescribing it.
  • Unwanted effects are more likely to occur with Lioresal (baclofen), so a cautious approach is needed while using the medication. Lioresal (baclofen) should be used with caution in older patients.
  • Lioresal (baclofen) is not suitable for everyone, so discuss all potential risks and benefits with a healthcare provider before starting treatment.
  • Lioresal (baclofen) may interact with other medications, so patients should inform their healthcare provider about all the medications they are taking.
  • Lioresal (baclofen) should not be abruptly discontinued, as it can cause withdrawal symptoms such as seizures or hallucinations.
  • Lioresal (baclofen) can cause drowsiness, dizziness, or impaired coordination, so patients should avoid driving or operating heavy machinery until they know how the medication affects them.
  • Lioresal (baclofen) should be used with caution in patients with a history of psychiatric disorders, as it may worsen symptoms such as depression or psychosis.
  • Lioresal (baclofen) should be used with caution in patients with kidney disease, as the medication is metabolized by the kidneys and may accumulate in the body.
  • Lioresal (baclofen) should be used with caution in patients with a history of seizures, as it may lower the seizure threshold and increase the risk of seizures.

Frequently Asked Questions (FAQ)

Can Lioresal DS be abruptly stopped?

No, Lioresal DS should not be abruptly stopped as it may cause withdrawal symptoms. Patients should consult with their healthcare provider to gradually taper off the medication if desired.

Is Lioresal DS addictive?

Lioresal DS is not considered to be addictive. However, like any medication, it is possible to become dependent on Lioresal DS with long-term use or higher doses.

How should Lioresal DS be stored?

Lioresal DS should be stored at room temperature and away from moisture and heat. It should also be kept out of reach of children.


It's important to purchase Lioresal DS from verified Canadian pharmacy.

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