Lioresal (Baclofen)

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Lioresal Brand
Dosage Quantity & Price
Baclofen (Generic alternate to Lioresal) Generic
Dosage Quantity & Price
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Lioresal is a muscle relaxant and antispastic medication that is used to treat severe spasticity caused by injury, nerve disorders, or multiple sclerosis (MS). Lioresal contains the active ingredient baclofen, which is a muscle relaxant. The exact mechanism of how baclofen works is not clear, but it is believed to work by acting on the spinal cord to reduce the transmission of messages between nerves. This reduces the amount of tension in the muscles, which can help ease muscle spasms and stiffness.

Uses and Dosage

To use Lioresal (Baclofen), take the tablet orally with or without food as directed by your doctor, typically three times daily. To minimize the risk of side effects, your doctor may advise starting at a low dose and gradually increasing it.

The typical dose of Baclofen for adults and children above 12 years is 5 mg to 20 mg orally three times daily. Your doctor may start you off with a low dose and adjust it based on how effective the medication is for you and your experience with side effects. The maximum daily dose of Baclofen is usually not more than 80 mg.

Side effect

Common Side Effects of Lioresal (Baclofen):

  • Confusion
  • Constipation
  • Dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • Headache
  • Increased need to urinate
  • Nausea
  • Passing urine more often
  • Sweating
  • Trouble sleeping
  • Unusual tiredness or weakness

Serious Side Effects of Lioresal (Baclofen):

  • Blurred vision
  • Convulsions
  • Difficult or troubled breathing
  • Dizziness
  • Drowsiness
  • Irregular, fast or slow, or shallow breathing
  • Lightheadedness
  • Loss of strength or energy
  • Low blood pressure
  • More frequent urination
  • Muscle pain or weakness
  • Ovarian cyst (fluid filled sac on your ovary)
  • Pale or blue lips, fingernails, or skin
  • Sleepiness or unusual drowsiness
  • Trouble sleeping
  • Unusual weak feeling
  • Unusually slow or troubled breathing

Form and Strength

Lioresal (Baclofen) is available in the following forms and strengths:

Lioresal: Tablet

  • 10 mg

Baclofen: Tablet

  • 10 mg


  • People who are allergic to baclofen should not use Lioresal.
  • Lioresal should be used with caution in people with kidney disease; a dosage adjustment may be necessary.
  • Lioresal should be used with caution in people with liver disease; a dosage adjustment may be necessary.
  • Lioresal should be used with caution in people with heart disease.
  • Lioresal can worsen symptoms of depression or other psychiatric conditions.
  • Lioresal should be used with caution in pregnant or breastfeeding women.
  • Lioresal can cause drowsiness, dizziness, or confusion, which can impair your ability to drive or operate machinery. Avoid these activities until you know how Lioresal affects you. Talk to your doctor about any medical conditions you have or medications you are taking before using Lioresal.
  • Lioresal should not be stopped suddenly as it can cause withdrawal symptoms such as hallucinations, seizures, and high fever. The medication should be gradually reduced under a doctor's supervision.
  • Lioresal can enhance the effects of alcohol, limit alcohol consumption while taking this medication.
  • Lioresal can interact with other medications, including drugs that affect the central nervous system, such as opioids, benzodiazepines, and tricyclic antidepressants. It is important to talk to your doctor about all medications you are taking before using Lioresal.
  • Lioresal should be discontinued before any surgeries as it can interfere with anesthesia. It is important to discuss any potential risks and benefits of using Lioresal with your doctor before starting the medication.

Frequently Asked Questions (FAQ)

What do I need to know if I am using Lioresal Intrathecal?

All patients and caregivers should receive information on the risks of the treatment. Your doctor should give you information of the signs and symptoms of receiving too much or too little medication (overdose or withdrawal) and what to do if you notice those symptoms.

Is Lioresal addictive?

Lioresal is not considered to be addictive. However, it can cause withdrawal symptoms if it is stopped suddenly. Gradually reduce the dosage under a doctor's supervision.

Can Lioresal be taken during pregnancy or while breastfeeding?

Lioresal should be used with caution in pregnant or breastfeeding women. Talk to your doctor about the potential risks and benefits of using Lioresal during pregnancy or while breastfeeding.

Can I cut my baclofen tablet in half?

Yes. In fact, most baclofen tablets have a scored line on them to help you cut your tablet in half. If you are instructed to cut your baclofen tablet in half, use a pill splitter, instead of a knife. This will help make sure you split the tablet evenly and safely.


It's important to purchase Lioresal from verified Canadian pharmacy.

Additional information

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