Hygroton (Chlorthalidone) Shopper Approved

Prescription Prescription Required FormationFormulation: Tablet


We don't sell this brand-version medication.

Prescription Prescription Required FormationFormulation: Tablet


(Generic Alternative)

Select the prescribed dosage

Select the quantity to see the price.


We don't charge dispensing fee


Shipped and delivered directly to your doorstep


Hygroton is a prescription medication used to treat high blood pressure (hypertension) and fluid retention. It contains chlorthalidone. Chlorthalidone is classified as a diuretic or "water pill" and works by increasing the amount of urine produced by the body, especially when the medication is first started.

By lowering the level of blood pressure, chlorthalidone can help to prevent strokes, heart attacks, and kidney problems. Additionally, it is used to reduce excess salt and water in the body caused by conditions such as heart failure, liver disease, and kidney disease. By decreasing extra salt and water in the body, it also helps to reduce swelling (edema) and breathing problems caused by fluid in the lungs.

Uses and Dosage

Chlorthalidone tablets should be taken orally, usually once a day, with or without food, as directed by your doctor. To get the most benefit from the medication, use it regularly and try to take it at the same time each day. Take chlorthalidone tablet in the morning with a meal. It starts working in about two hours, so do not take it at night; otherwise, you will go to the bathroom more overnight. Avoid taking the tablet within 4 hours of bedtime to avoid having to get up to urinate.

If you have any questions about your dosing schedule or how to use the medication properly, consult your doctor or pharmacist. Avoid taking certain drugs to lower your cholesterol, such as bile acid-binding resins like cholestyramine or colestipol, within 2 hours before or 4 hours after taking Hygroton. Remember to keep taking the medication even if you feel well, as most people with high blood pressure do not feel sick.

Side Effect

Common Side Effects of Hygroton (Chlorthalidone):

  • Dizziness
  • Headache
  • High blood sugar for those with diabetes
  • Increased urination
  • Sensitivity to the sun

Serious Side Effects of Hygroton (Chlorthalidone):

  • Electrolyte changes
  • Gouty attacks for people with gout
  • Temporary muscle pain or weakness

Form and Strength

Hygroton (Chlorthalidone) is available in the following forms and strength:

Chlorthalidone: Tablet

  • 50 mg


  • Individuals with an allergy to chlorthalidone or sulfa-containing medications should not take Hygroton.
  • Hygroton can cause low blood pressure, so people who are dehydrated or taking other medications that lower blood pressure should use it with caution.
  • Hygroton can affect blood sugar levels and may interfere with diabetes medications.
  • Dehydration may occur while taking chlorthalidone, so be sure to drink enough water and discuss fluid intake with your doctor.
  • Use of Hygroton during pregnancy or while breastfeeding may not be recommended, so talk to your doctor.
  • Hygroton can lead to changes in electrolyte levels, causing low sodium, potassium, or magnesium. Regular blood tests may be required to monitor these levels.
  • Those with liver or kidney impairment should use caution when taking Hygroton, as the medication may exacerbate these conditions.
  • Hygroton may increase the risk of gout attacks, so people with a history of gout should discuss this medication with their doctor.
  • Hygroton may cause sensitivity to sunlight or ultraviolet light, so avoid prolonged exposure to these sources.
  • Hygroton may interact with other medications, including insulin, cholesterol-lowering drugs, and lithium, discuss any potential drug interactions with a doctor or pharmacist.

Frequently Asked Questions (FAQ)

How long does chlorthalidone take to work?

The diuretic effect will usually start within about 2-3 hours after taking your dose. You can expect to see blood pressure changes within a few days of starting the tablet.

Can Hygroton be taken during pregnancy or breastfeeding?

Hygroton may not be safe to take during pregnancy or while breastfeeding, discuss the risks and benefits with a healthcare professional.

Can Hygroton cause dehydration?

One of the main side effects of Hygroton is increased urination, which can lead to dehydration. Drink plenty of fluids and monitor for signs of dehydration, such as dark urine, dry mouth, and thirst.

How long does Hygroton stay in your system?

The effects of Hygroton wear off after about 24 hours, but the medication can stay in your system for several days after the last dose.

Does Hygroton cause weight gain?

One of the main effects of Hygroton is fluid loss, which can lead to weight loss. However, some people may experience weight gain if they retain water due to changes in electrolyte levels.


Additional information

Generic name:






Quantities Available:

100, 200


Additional Information Book

If you have any Questions

Call Us

call us toll free


OR Email us at

[email protected]

Why customers love Online Pharmacies Canada

Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.

Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.

Onlinepharmaciescanada.com widget logo

Ordering Hygroton just became easier

Discover Our Users' Stories!

Watch how Online Pharmacies Canada is helping customers save money on their medications.

Learn how Online Pharmacies Canada is helping customers save money on their medications.

Learn more about who we are

Generic vs Brand Name Drugs: Is There a Difference?

Generic vs Brand Name Drugs: Is There a Difference?

Many people want to know the difference between generic and brand-name drugs, especially when it comes to their health and their wallets. Knowing what sets these medications apart can help…

CIPA Certified Pharmacies Recognized as Safe in the US

Why does Canadian pharmacy require a prescription?

A medical prescription (often abbreviated as Rx) is a formal written order issued by a licensed healthcare professional, such as a physician, nurse practitioner, or dentist. This order authorizes a…

Affordable medications? You found what you�ve been looking for

List of general drug categories: A to Z

A drug category is a way of organizing medications into groups based on shared characteristics. These characteristics can include their chemical structure, how they work in the body, what they’re…

Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Hygroton (Chlorthalidone). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Hygroton (Chlorthalidone).