Indications
Accuretic is a medication that is used to treat high blood pressure, also known as hypertension. It is a fixed-dose combination medication that contains two active ingredients: quinapril and hydrochloride. Quinapril belongs to a class of drugs known as ACE inhibitors and works by relaxing blood vessels so blood can flow more easily. Hydrochlorothiazide belongs to a class of drugs known as diuretics/"water pills." It works by causing you to make more urine. This helps your body get rid of extra salt and water.
Uses and Dosage
Accuretic is available as a tablet that should be taken by mouth with or without food, in accordance with the directions provided by your doctor. Typically, the medication is taken once daily in the morning. To minimize the likelihood of needing to wake up to urinate, take the medication at least 4 hours before bedtime.
To gain the most benefit from the medication, take it regularly, at the same time each day. Even if you are feeling well, continue taking Accuretic, as most people with high blood pressure do not experience any noticeable symptoms.
The starting dose for Accuretic is typically one tablet of 10mg/12.5mg taken once daily. The largest dose given to people was 40 mg of quinapril and 25 mg of hydrochlorothiazide by mouth once daily. If your doctor has recommended a different dosage than this, follow their specific instructions regarding dosage.
Side Effect
Common Side Effects of Accuretic (Quinapril/HCTZ):
- Constipation
- Cough
- Diarrhea
- Dizziness
- Fatigue/tiredness
- Frequent urination
- Headache
Serious Side Effects of Accuretic (Quinapril/HCTZ):
- Difficulty getting or maintaining an erection
- Indigestion
- Muscle pain
- Nausea/vomiting
- Stomach pain
Form and Strength
Accuretic (Quinapril/HCTZ) is available in the following forms and strength:
Accuretic: Tablet
- 10/12.5mg
- 20/12.5mg
Quinapril/HCTZ: Tablet
- 10/12.5mg
Caution
- Accuretic is not recommended during pregnancy, especially in the second and third trimesters, as it can cause harm to the developing fetus. Do not take Accuretic while breastfeeding, as it can pass into breast milk and harm the infant.
- If you miss a dose of Accuretic, take it as soon as you remember. However, if it is close to the time of your next scheduled dose, skip the missed dose and take your next dose as scheduled. Do not double up on doses to make up for a missed one.
- Drinking alcohol while taking Accuretic can increase the risk of certain side effects, such as dizziness or fainting. Avoid excessive alcohol consumption while taking this medication.
- Accuretic can interact with a number of medications, including other blood pressure medications, nonsteroidal anti-inflammatory drugs (NSAIDs), and certain antibiotics. Inform your healthcare provider of all medications and supplements you are taking before starting Accuretic.
- You should not use this medicine if you have ever had angioedema, if you are unable to urinate, or if you are allergic to sulfa drugs or to any ACE inhibitor. Do not take Accuretic within 36 hours before or after taking medicine that contains sacubitril (such as Entresto).
- If you have diabetes, do not use Accuretic together with any medication that contains aliskiren (a blood pressure medicine).
Frequently Asked Questions (FAQ)
Can Accuretic be used to treat other conditions besides high blood pressure?
Accuretic is specifically approved to treat high blood pressure and is not recommended for other conditions.
How long does it take for Accuretic to start working?
Accuretic may take several weeks to start lowering blood pressure effectively. Follow your healthcare provider's instructions closely and keep to all scheduled appointments.
How should I store Accuretic?
Store Accuretic at room temperature, away from moisture and heat. Keep it out of reach of children.
Can Accuretic cause any interactions with food or drinks?
Accuretic can interact with certain types of food, such as grapefruit or grapefruit juice, which can increase the level of the medication in the bloodstream and increase the risk of side effects. Ask your healthcare provider about safe food and drink options while taking Accuretic.
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