Pregnancy
Do not use Accuretic during pregnancy.
Accuretic contains quinapril, an ACE inhibitor that can cause serious injury or death to a developing baby.
If you become pregnant while taking Accuretic, contact your healthcare provider right away. The medication should generally be stopped as soon as pregnancy is detected.
Breastfeeding
Tell your healthcare provider if you are breastfeeding.
Both quinapril and hydrochlorothiazide can pass into breast milk.
Because of the potential for serious side effects in a nursing baby, your healthcare provider may recommend stopping Accuretic or stopping breastfeeding, depending on your treatment needs.
Alcohol
Alcohol can increase some of the blood-pressure-lowering effects of Accuretic.
This may make you more likely to experience:
- Dizziness
- Lightheadedness
- Fainting
Limit or avoid alcohol until you know how Accuretic affects you.
Drug Interactions
Tell your healthcare provider about all medications, vitamins, and supplements you take.
Accuretic may interact with medications such as:
- Other blood pressure medications
- Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen or naproxen
- Lithium
- Potassium supplements or potassium-containing salt substitutes
- Certain diuretics
- Aliskiren
- Sacubitril/valsartan
Some combinations may increase the risk of low blood pressure, kidney problems, or abnormal potassium levels.
Angioedema
Do not use Accuretic if you have previously developed angioedema from an ACE inhibitor.
Angioedema can cause sudden swelling of the:
Seek emergency medical attention if you develop swelling or difficulty breathing or swallowing while taking Accuretic.
Sacubitril/Valsartan
Do not take Accuretic within 36 hours before or after taking a medication that contains sacubitril, such as sacubitril/valsartan.
Using these medications too close together can increase the risk of serious angioedema.
Aliskiren and Diabetes
If you have diabetes, do not take Accuretic together with a medication that contains aliskiren.
This combination can increase the risk of low blood pressure, high potassium levels, and kidney problems.
Problems With Urination
Do not take Accuretic if you are unable to produce urine, a condition called anuria.
Hydrochlorothiazide works through the kidneys and should not be used in people with anuria.
Sulfonamide Allergy
Accuretic contains hydrochlorothiazide, which is a sulfonamide-derived medication.
Do not use Accuretic if you have had a serious hypersensitivity reaction to hydrochlorothiazide or another sulfonamide-derived drug.
What to Do If You Miss a Dose
If you miss a dose of Accuretic, take it as soon as you remember.
If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule.
Do not take two doses at the same time or take extra tablets to make up for the missed dose.
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