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Aldactazide

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Prescription Prescription Required FormationFormulation: Scored Tablet

Spironolactone/Hctz

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Aldactazide contains two active ingredients: spironolactone and hydrochlorothiazide. It is a prescription medication used to treat high blood pressure and certain conditions that cause fluid buildup in the body.

Both ingredients are diuretics, sometimes called water pills. They help the kidneys remove extra salt and water through the urine.

High Blood Pressure

Aldactazide may be used to treat hypertension, also known as high blood pressure.

It is usually prescribed when spironolactone or hydrochlorothiazide alone does not control blood pressure well enough.

Lowering high blood pressure can help reduce strain on the heart and blood vessels. It may also lower the risk of serious complications such as heart attack, stroke, and kidney problems.

Fluid Retention and Swelling

Aldactazide may also be used to manage edema, which is swelling caused by excess fluid in the body.

Fluid buildup may cause:

  • Swelling in the feet, ankles, legs, or abdomen
  • Sudden weight gain
  • Shortness of breath
  • Tight or uncomfortable skin
  • Difficulty moving comfortably

Aldactazide helps the body remove this extra fluid.

Congestive Heart Failure

In congestive heart failure, the heart may not pump blood effectively. This can cause fluid to collect in the lungs, legs, ankles, or other parts of the body.

Aldactazide may help reduce swelling and make breathing easier by removing excess fluid. It may also reduce some of the workload placed on the heart.

Liver Cirrhosis

Aldactazide may be prescribed for people with liver cirrhosis who develop edema or ascites.

Ascites is a buildup of fluid inside the abdomen. It may cause abdominal swelling, discomfort, reduced appetite, or shortness of breath.

Aldactazide helps the kidneys remove extra salt and water, which may reduce this fluid buildup.

Nephrotic Syndrome

Nephrotic syndrome is a kidney condition that causes large amounts of protein to leak into the urine. This can lead to fluid retention and swelling.

Aldactazide may be used to reduce swelling when other treatments or dietary changes are not enough.

How Aldactazide Works

Aldactazide combines two types of diuretics that work in different ways.

Spironolactone Helps Prevent Potassium Loss

Spironolactone is a potassium-sparing diuretic. It blocks the effects of a hormone called aldosterone.

Aldosterone normally causes the body to hold on to salt and water while removing potassium. By blocking this hormone, spironolactone helps the body release extra salt and water while reducing potassium loss.

Hydrochlorothiazide Removes Extra Salt and Water

Hydrochlorothiazide is a thiazide diuretic.

It increases the amount of salt and water removed by the kidneys. This helps reduce fluid buildup and may lower blood pressure.

Combined Effect

Using spironolactone and hydrochlorothiazide together may provide a stronger diuretic effect than either medication alone.

The combination may also help balance potassium levels. However, potassium can still become too high or too low, so blood tests may be needed during treatment.

Take Aldactazide exactly as prescribed and attend all follow-up appointments so your healthcare provider can monitor your blood pressure, kidney function, and electrolyte levels.

Take Aldactazide exactly as prescribed by your healthcare provider. It is taken by mouth and may be taken with or without food.

The tablets are usually taken once or twice daily. Your dose and schedule will depend on your medical condition, blood pressure, fluid retention, kidney function, and response to treatment.

Take Aldactazide at approximately the same time each day. Taking it regularly helps the medication work effectively.

Best Time to Take Aldactazide

Aldactazide increases urination because it helps the body remove extra salt and water.

Take your last daily dose at least four hours before bedtime. This may reduce the need to wake up during the night to urinate.

Your healthcare provider may recommend taking it in the morning or dividing the dose between the morning and early afternoon.

Dosage for Fluid Retention

For swelling caused by congestive heart failure, liver cirrhosis, or nephrotic syndrome, the usual dose may be:

100 mg of spironolactone and 100 mg of hydrochlorothiazide once or twice daily.

The dose may be adjusted based on how much fluid is retained, how well the medication works, and the results of blood tests.

Dosage for High Blood Pressure

For high blood pressure, the usual dose may range from:

50 mg of spironolactone and 50 mg of hydrochlorothiazide to 100 mg of spironolactone and 100 mg of hydrochlorothiazide once or twice daily.

Your healthcare provider will prescribe the lowest dose that controls your blood pressure safely.

Missed Dose

Take a missed dose as soon as you remember.

However, skip the missed dose if it is almost time for your next scheduled dose. Continue with your regular dosing schedule.

Do not take two doses at once or take extra tablets to make up for a missed dose.

Continuing Treatment

High blood pressure often does not cause noticeable symptoms. Continue taking Aldactazide even if you feel well.

Do not change your dose or stop taking the medication without speaking with your healthcare provider. Regular appointments and blood tests may be needed to monitor your blood pressure, kidney function, and electrolyte levels.

Common Side Effects of Aldactazide (Spironolactone/Hctz):

  • Dizziness
  • Drowsiness
  • Hair loss
  • Itching
  • Lack of energy
  • Leg cramps
  • Feeling unsteady
  • Headache
  • Ill feeling
  • Mouth sores
  • Vomiting

Serious Side Effects of Aldactazide (Spironolactone/Hctz):

  • Breast swelling and tenderness
  • Chills
  • Confusion
  • Easy bruising
  • Extreme thirst
  • Eye pain
  • Increased urination
  • Leg discomfort
  • Lightheadedness
  • Limp feeling
  • Loss of coordination
  • Muscle weakness
  • Purple or red pinpoint spots under your skin
  • Severe weakness
  • Slow heart rate
  • Slurred speech
  • Sore throat
  • Sudden weakness
  • Tingly feeling
  • Uneven heart rate
  • Unusual bleeding
  • Vision problems
  • Weak pulse
  • Yellowing of your skin or eyes (jaundice)

Aldactazide (Spironolactone/Hctz) is available in the following forms and strength:

Spironolactone/Hctz: Scored Tablet

  • 25/25mg
  • 50/50mg

Allergies and Conditions That Prevent Use

Do not take Aldactazide if you are allergic to spironolactone, hydrochlorothiazide, thiazide diuretics, or certain sulfonamide-derived medications.

Aldactazide may also be unsuitable for people who:

  • Cannot produce urine
  • Have severe kidney impairment
  • Have high potassium or calcium levels
  • Have Addison’s disease
  • Have another condition that causes high potassium

Tell your healthcare provider about all kidney, liver, and adrenal gland conditions before starting treatment.

Medication Interactions

Aldactazide may interact with several medications. Some combinations may affect kidney function, blood pressure, or electrolyte levels.

Tell your healthcare provider about all prescription medications, over-the-counter products, vitamins, herbal products, and supplements you use.

Important interactions may occur with:

  • ACE inhibitors
  • Angiotensin receptor blockers
  • Nonsteroidal anti-inflammatory drugs, also called NSAIDs
  • Potassium supplements
  • Potassium-containing salt substitutes
  • Lithium
  • Other diuretics

Medications that increase potassium levels

Do not start or stop another medication without speaking with your healthcare provider.

High Potassium Levels

Spironolactone helps the body retain potassium. In some people, this may cause hyperkalemia, which means the potassium level in the blood becomes too high.

High potassium can be dangerous and may affect the heart.

Contact your healthcare provider if you develop:

  • Muscle weakness
  • Unusual tiredness
  • Numbness or tingling
  • Nausea
  • A slow, fast, or irregular heartbeat
  • Chest discomfort

Regular blood tests may be needed to monitor potassium and kidney function.

Potassium Supplements and Food

Do not take potassium supplements or use potassium-containing salt substitutes unless your healthcare provider recommends them.

You may also be advised to limit foods that contain very large amounts of potassium. Do not make major dietary changes without medical guidance, as your potassium needs depend on your blood-test results and overall health.

Lithium Interaction

Aldactazide may reduce the amount of lithium removed by the kidneys. This can cause lithium levels to become too high and increase the risk of toxicity.

Signs of lithium toxicity may include:

  • Severe shaking
  • Confusion
  • Vomiting or diarrhoea
  • Poor coordination
  • Muscle weakness
  • Extreme drowsiness

Tell your healthcare provider if you take lithium. Your lithium level may need closer monitoring.

Dizziness and Low Blood Pressure

Aldactazide may cause dizziness, light-headedness, or fainting, especially when you stand up quickly.

Rise slowly from a sitting or lying position. Use caution when driving or operating machinery until you know how the medication affects you.

Contact your healthcare provider if dizziness is severe, persistent, or causes you to faint.

Blood Sugar Changes

Hydrochlorothiazide may increase blood sugar levels. This is especially important for people with diabetes or prediabetes.

Your healthcare provider may monitor your blood sugar more closely during treatment. Diabetes medication may need to be adjusted.

Contact your healthcare provider if you experience increased thirst, frequent urination, blurred vision, or unusual tiredness.

Low Sodium Levels

Aldactazide may lower the amount of sodium in the blood. This condition is called hyponatremia.

Possible symptoms include:

  • Headache
  • Nausea
  • Muscle cramps
  • Weakness
  • Confusion
  • Severe tiredness
  • Seizures in serious cases

The risk may be higher in older adults and people with liver, kidney, or heart conditions. Blood tests may be required to monitor sodium and other electrolyte levels.

Gout

Aldactazide may increase uric acid levels and trigger or worsen gout in some people.

Tell your healthcare provider if you have gout or a history of high uric acid.

Contact them if you develop sudden severe pain, redness, warmth, or swelling in a joint, especially the big toe.

Regular Monitoring

Your healthcare provider may regularly check:

  • Blood pressure
  • Kidney function
  • Potassium levels
  • Sodium levels
  • Blood sugar
  • Uric acid levels
  • Fluid balance

Attend all scheduled blood tests and follow-up appointments. Do not change your dose or stop taking Aldactazide without medical guidance.

Can Aldactazide Be Taken With Food?

Yes. Aldactazide may be taken with or without food. Taking it with food may help reduce stomach upset. Try to take each dose the same way and at approximately the same time each day.

Is It Safe to Drive While Taking Aldactazide?

Aldactazide may cause dizziness, light-headedness, or weakness, especially when treatment first begins or after the dose is increased. Do not drive, operate machinery, or perform activities that require alertness until you know how the medication affects you. Stand up slowly from a sitting or lying position to reduce the risk of dizziness or fainting.

How Long Does Aldactazide Take to Work?

Aldactazide begins helping the body remove extra salt and water soon after a dose. You may notice more frequent urination within several hours. Swelling may begin to improve within a few days. Its full effect on blood pressure may take several weeks of regular use. Continue taking Aldactazide as prescribed, even if you do not feel different. High blood pressure often does not cause noticeable symptoms.

Can Aldactazide Be Taken During Pregnancy or Breastfeeding?

Tell your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. Aldactazide is generally avoided during pregnancy unless a healthcare provider decides that the expected benefit is greater than the possible risk. Diuretics are not normally used to treat swelling caused by pregnancy. The ingredients may pass into breast milk or affect milk production. Your healthcare provider will help determine whether to continue the medication, use another treatment, or stop breastfeeding. Do not start or stop Aldactazide during pregnancy or breastfeeding without medical guidance.

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Additional Information Book
Generic name:

Spironolactone/Hctz

Formulation:

Scored Tablet

Strength(s):

25/25mg, 50/50mg

Quantities Available:

100

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Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.

Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.

How to Order

How much Aldactazide can I order at once from a Canadian pharmacy?

When ordering Aldactazide (spironolactone/hydrochlorothiazide) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure continuous management of conditions like hypertension and edema without frequent refills.

Here’s what you need to know:

Dosage and Quantity: Aldactazide is available in various strengths, such as spironolactone 25 mg/hydrochlorothiazide 25 mg. Depending on your healthcare provider’s instructions, Aldactazide is usually taken once daily. Therefore, for a 90-day supply, this means you would need to order 90 tablets (1 tablet daily x 90 days).

Do you sell spironolactone/hydrochlorothiazide?

Yes, we sell spironolactone/hydrochlorothiazide on our website, where you can enjoy low prices. To purchase spironolactone/hydrochlorothiazide, you will need a valid prescription from your healthcare provider. We require this prescription to dispense the medication safely and legally. During the ordering process, you can conveniently submit your prescription by mail, fax, or upload it through your online account.

Do you offer shipping of Aldactazide (spironolactone/hydrochlorothiazide) to the United States?

Yes, we ship Aldactazide (spironolactone/hydrochlorothiazide) to both the United States and Puerto Rico.

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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Aldactazide (Spironolactone/Hctz). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Aldactazide (Spironolactone/Hctz).