Indications
Coreg CR (active ingredient: carvedilol) is a prescription medication indicated for the following:
- Heart Failure: Coreg CR is used for the treatment of chronic heart failure (CHF) in adults to improve symptoms, increase survival, and reduce the need for hospitalization.
- Hypertension: Coreg CR is indicated for the treatment of hypertension (high blood pressure) in adults to lower blood pressure.
- Left Ventricular Dysfunction Following Myocardial Infarction: Coreg CR is used for the treatment of left ventricular dysfunction following myocardial infarction (heart attack) to reduce cardiovascular mortality.
Coreg CR belongs to a class of drugs known as beta-blockers, which work by blocking the action of certain natural substances in the body such as adrenaline on the heart and blood vessels. This results in a slowing of the heart rate, reduction of blood pressure, and improved heart function.
Use and Dosage
Coreg CR is available in the form of capsules that need to be taken by mouth with food as directed by your doctor, usually once daily in the morning. However, its generic version Carvedilol Phosphate is available as CR tablets. Swallow the capsule/ tablet whole and do not crush or chew it.
If you are unable to swallow the capsule/ tablet, you may open the capsule/ tablet and sprinkle the beads over cool, smooth applesauce. However, you should not chew the mixture as doing so may cause the drug to be released too quickly, leading to increased side effects. Make sure to swallow the mixture right away. Do not prepare the mixture ahead of time for later use.
Your doctor will determine the appropriate dosage based on your medical condition and response to treatment. To reduce the risk of side effects, your doctor may direct you to start at a low dose and gradually increase it. It is important to follow your doctor's instructions carefully.
Take the capsule/ tablet regularly to get the most benefit from it and remember to take it at the same time each day. For high blood pressure, it may take 1 to 2 weeks before you feel the full benefit of this drug. Keep taking the capsule/ tablet even if you feel well, as most people with high blood pressure do not feel sick.
Side Effects
Common Side Effects of Coreg CR (Carvedilol Phosphate):
- Diarrhea
- Dizziness
- Dry eyes
- Problems wearing contact lenses
- Slow heartbeats
- Weight gain
Serious Side Effects of Coreg CR (Carvedilol Phosphate):
- Chest pain
- Chest tightness
- Cold feeling or numbness in your fingers or toes
- Dry cough
- Dry mouth and
- Fruity breath odor
- Increased thirst
- Increased urination
- Lightheadedness
- Rapid weight gain
- Shortness of breath
- Slow or uneven heartbeats
- Swelling
- Wheezing
Forms and Strength
Coreg CR (Carvedilol Phosphate) is available in the following forms and strength:
Coreg CR: Capsule
- 20 mg
Carvedilol Phosphate: CR Tablet
- 10 mg
- 20 mg
- 40 mg
Cautions
- Carvedilol Phosphate may cause drowsiness, dizziness, or fainting. Patients should avoid activities such as driving or operating heavy machinery until they know how the medication affects them.
- Patients with a history of heart, lung or liver disease, diabetes, or thyroid problems should inform their healthcare provider before taking Carvedilol Phosphate.
- Coreg CR may interact with other medications, so patients should inform their healthcare provider about any other medications they are taking.
- Patients with a history of asthma or other breathing problems should be cautious when taking Coreg CR as it may worsen their symptoms.
- Women who are pregnant or breastfeeding should consult their healthcare provider before taking Carvedilol Phosphate. Discuss the risks and benefits of taking any medication with a healthcare provider before starting a new medication.
- Coreg CR may cause low blood pressure. Patients should inform their healthcare provider if they experience symptoms such as dizziness, lightheadedness, or fainting.
- Patients with a history of kidney disease should be monitored closely while taking Coreg CR.
- Coreg CR may mask the symptoms of low blood sugar in patients with diabetes. Patients with diabetes should monitor their blood sugar levels closely while taking Coreg CR.
- Patients with a history of depression or mental illness should be cautious when taking Coreg CR as it may worsen their symptoms.
- Coreg CR may cause changes in blood sugar and cholesterol levels, so patients should have their levels checked regularly while taking the medication.
- Patients with a history of severe allergic reactions should inform their healthcare provider before taking Coreg CR as it may increase the risk of an allergic reaction. Patients who are allergic to any ingredients in Coreg CR should not take it.
Frequently Asked Questions (FAQ)
Is Coreg CR available in generic form?
Yes, Coreg CR is available in generic form under the name carvedilol phosphate. The generic version may be less expensive than the brand-name version.
Can Coreg CR be taken with food?
Yes, Coreg CR can be taken with or without food. However, taking it with a high-fat meal may increase blood levels of the medication.
What should I do if I miss a dose of Coreg CR?
If you miss a dose of Coreg CR, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
How long does it take for Coreg CR to start working?
It may take several weeks for Coreg CR to start working. You may not feel the full benefits of the medication for several months.
Can Coreg CR be taken at night?
Coreg CR can be taken at any time of day, but it is usually taken in the morning with breakfast to help prevent dizziness or fainting.
Resources
- https://www.webmd.com/drugs/2/drug-146269/coreg-cr-oral/details
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/022012lbl.pdf
- https://www.drugs.com/mtm/coreg-cr.html
- https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=06400a4c-42b4-440a-92b4-1f47f98ac7ba
- https://www.rxlist.com/coreg-cr-drug.htm
- https://coregcr.com/
REVIEWS