Inspra (Eplerenone)

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Inspra Brand
Dosage Quantity & Price
Eplerenone (Generic alternate to Inspra) Generic
Dosage Quantity & Price
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Table of contents:

Inspra is a prescription medication used to treat high blood pressure (hypertension) and heart failure post myocardial infarction. It contains a drug called eplerenone, which is an aldosterone receptor antagonist. It works by blocking the effects of aldosterone, a hormone that can cause salt and fluid retention in the body, contributing to hypertension and heart failure. Aldosterone receptor antagonists like eplerenone are also used to treat other conditions, such as hyperaldosteronism and diabetic nephropathy.

Inspra is oral medication prescribed to enhance the survival rate of stable patients suffering from congestive heart failure (CHF) and left ventricular (LV) systolic dysfunction caused by acute myocardial infarction (MI). By reducing blood pressure levels, it helps in preventing fatal and non-fatal cardiovascular events such as strokes and myocardial infarction.

Uses and Dosage

Inspra (Eplerenone) is an orally administered tablet that is typically prescribed once or twice daily, or as instructed by your doctor. The tablet can be taken with or without food and should be swallowed whole with water immediately after. If you need to cut the tablet, seek assistance from a pharmacist. Take Inspra regularly and as prescribed, so it may be helpful to create a dosing schedule to avoid missing doses.

Do not change your dosage or frequency without consulting your doctor, as it is based on your individual medical condition and response to the medication. Additionally, do not stop taking Inspra suddenly, as doing so may worsen your condition.

The recommended dosages of Inspra (Eplerenone) may vary depending on the individual's medical condition and response to the medication. However, the typical starting doses for Inspra for certain conditions are as follows:

  • For heart failure: 25 milligrams (mg) once daily, which may be increased up to 50 mg once daily as needed and tolerated.
  • For hypertension: 50 mg once daily.

The doses may need to be adjusted based on the individual's medical condition and response to treatment. Follow your doctor's instructions regarding the dosages and do not adjust the dosages or frequency of administration without consulting with a healthcare professional.

Side effect

Common Side Effects of Inspra (Eplerenone):

  • Nausea
  • Headache
  • Dizziness
  • Abdominal pain
  • Diarrhea
  • Breast tenderness

Serious Side Effects of Inspra (Eplerenone):

  • Chest pain
  • Diarrhea
  • Difficulty breathing
  • Enlarged or sore breasts in males
  • Fast or irregular heartbeats
  • Hives
  • Lightheadedness
  • Little or no urination
  • Loss of movement
  • Nausea
  • Severe stomach pain
  • Swelling in your feet or lower legs
  • Swelling of your face, lips, tongue, or throat
  • Symptoms of high potassium level in the blood or hyperkalemia (muscle weakness, slow and irregular heartbeat)
  • Tingly feeling
  • Unusual vaginal bleeding
  • Vomiting
  • Weakness

Form and Strength

Inspra (Eplerenone) is available in the following forms and strength

路聽聽聽聽聽聽聽 Inspra: Tablet

  • 25 mg
  • 50 mg

路聽聽聽聽聽聽聽 Eplerenone: Tablet

  • 25 mg
  • 50 mg


  • Eplerenone may cause hyperkalemia (high potassium levels), which can be dangerous for people with certain medical conditions
  • Inspra may interact with other medications, such as certain antibiotics, antifungal drugs, and HIV (Human Immunodeficiency Virus) medications
  • Eplerenone may not be safe for people with severe liver disease or moderate to severe kidney disease
  • Inspra may cause dizziness or fainting when standing up, especially in older adults
  • Eplerenone may increase the risk of certain cardiovascular events in people with heart failure and diabetes.
  • Inspra may increase potassium levels in the blood, which can be harmful for people with certain medical conditions, such as kidney disease, diabetes, and heart disease.
  • Inspra may cause electrolyte imbalances, such as elevated levels of potassium, sodium, or magnesium.
  • Inspra may cause an allergic reaction in some people, which can be severe and require immediate medical attention.
  • Inspra may interact with certain herbal supplements, such as licorice root and St. John's wort.
  • Inspra may cause liver damage, although this is rare.

Frequently Asked Questions (FAQ)

How should Inspra be taken?

Inspra should be taken exactly as prescribed by a healthcare professional. It can be taken with or without food and should be swallowed whole with a glass of water.

Can Inspra be used during pregnancy or while breastfeeding?

Inspra is not recommended for use during pregnancy or breastfeeding, as it may harm a developing fetus or infant. Discuss any potential risks and benefits with a healthcare professional.

How long does it take for Inspra to start working?

The exact time it takes for Inspra to start working may vary depending on individual health conditions and other factors.

Can Inspra be taken with other medications?

Inspra may interact with other medications, such as certain antibiotics, antifungal drugs, and HIV medications, so inform a healthcare professional of any medications being taken. It may also increase the risk of certain cardiovascular events in people with heart failure and diabetes.

What should I do if I miss a dose of Inspra?

If a dose of Inspra is missed, it should be taken as soon as possible, unless it is almost time for the next dose. In that case, it is best to skip the missed dose and resume the normal dosing schedule. Do not take a double dose to make up for a missed dose.


It's important to purchase Inspra from verified Canadian pharmacy.

Additional information

Generic name:



Film Coated Tablet, Tablet


25mg, 50mg

Quantities Available:

84, 90, 100