Indications
Avapro generically known as Irbesartan indicated for the treatment of high blood pressure (hypertension), congestive heart failure, diabetic nephropathy, and other cardiovascular diseases. It belongs to a class of drugs known as angiotensin II receptor blockers (ARBs). It works by blocking the hormones that narrow blood vessels, allowing for greater blood flow.
AVAPRO (irbesartan) is used to treat hypertension, helping to lower blood pressure and reduce the risk of fatal cardiovascular events.
AVAPRO can be used alone or in combination with other antihypertensive medications. As part of comprehensive cardiovascular risk management, blood pressure control should be combined with other treatments, such as lipid management, diabetes management, antithrombotic therapy, smoking cessation, exercise, and limited sodium intake.
Uses and Dosage
AVAPRO is available as unscored tablets that can be taken with or without food. It is usually taken once daily. It can be taken alone or in combination with other antihypertensive agents to help control blood pressure. The dosage is typically based on your medical condition and response to treatment.
The recommended starting dose of AVAPRO to control blood pressure is 150 mg taken once daily. Depending on the patient's response to the medication, the dosage may be increased up to a maximum of 300 mg taken once daily as needed. In cases where additional control of blood pressure is desired, an additional antihypertensive drug may be added, or the dosage of AVAPRO may be increased to 100 mg once daily.
For patients with Nephropathy caused by Type 2 Diabetes, the recommended dose of Avapro is 300 mg taken once daily. However, strictly follow the instructions of your doctor when taking this medication, as higher doses than the recommended maximum may cause adverse effects.
Side Effects
Serious Side Effects of Irbesartan Include:
- Confusion
- Dark-colored urine
- Fever
- Lightheadedness
- Little or no urination
- Loss of appetite
- Pain in your side or lower back
- Rapid weight gain
- Swelling
- Tenderness or weakness
- Unexplained muscle pain
- Unusual tiredness
- Vomiting
Common Side Effects of Avapro Include:
- Diarrhea
- Heartburn
- Upset stomach
- Tired feeling
Form and Strength
Avapro and its generic alternative Irbesartan are available in the following forms and strengths:
Avapro: Tablet
- 75 mg
- 150 mg
- 300 mg
Irbesartan: Tablet
- 75 mg
- 150 mg
Caution
- Upon detection of pregnancy, discontinuation of AVAPRO is imperative. Medications that act on the renin-angiotensin system are known to cause severe damage, including death, to the unborn child.
- Before taking AVAPRO, discuss your medical history with your doctor or pharmacist, particularly if you have had any liver disease, dehydration, or abnormally elevated levels of potassium in your blood.
- Before taking any potassium supplements, or salt substitutes containing potassium, consult your doctor or pharmacist, as AVAPRO may increase your potassium levels.
- AVAPRO can make you dizzy, avoid driving, operating machinery, or engaging in any other activity that requires alertness until you are sure you can do it safely.
- Alcohol or marijuana (cannabis) can also make you dizzier and should be avoided or limited. If you are using marijuana (cannabis), talk to your doctor about it.
- AVAPRO may also cause dehydration, so be sure to drink plenty of fluids while taking it. If you have any questions or concerns about taking Avapro, talk to your doctor.
Frequently Asked Questions (FAQ)
How long does irbesartan (Avapro) take to work?
Irbesartan (Avapro) can lower blood pressure within hours of the first dose. It may take up to 2 weeks of daily use before you see the full effect.
Can I take AVAPRO (irbesartan) with other medications?
Yes, but AVAPRO may interact with other medications, including potassium supplements and salt substitutes. Talk to your doctor before taking any other medications while taking AVAPRO (irbesartan).
Can I take Avapro (irbesartan) if I have high cholesterol?
Yes, Avapro (irbesartan) can be taken if you have high cholesterol. However, you should also be aware that Avapro can interact with some cholesterol-lowering medications.
Should I take irbesartan at night or in the morning?
Take irbesartan tablets once a day. Your doctor may suggest that you take your first dose before bedtime because it can make you dizzy. After the very first dose, you can take Avapro at any time of the day.
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