Pregnancy
Azor carries a boxed warning for fetal toxicity. Do not use Azor during pregnancy.
Olmesartan affects the renin-angiotensin system and can cause serious harm or death to an unborn baby, especially during the second and third trimesters.
Stop taking Azor and contact your healthcare provider as soon as possible if you become pregnant or think you may be pregnant.
Low Blood Pressure
Azor may cause blood pressure to become too low, leading to dizziness, weakness, lightheadedness, or fainting.
The risk may be higher if you:
- Are dehydrated
- Take high doses of diuretics, also called water pills
- Follow a low-salt diet
- Have ongoing vomiting or diarrhea
Stand up slowly from a sitting or lying position. Contact your healthcare provider if dizziness is severe or you faint.
Kidney Problems
Azor may cause new or worsening kidney problems, particularly in people who already have kidney disease, severe heart failure, dehydration, or reduced blood flow to the kidneys.
Your healthcare provider may order blood tests to monitor kidney function during treatment.
Contact your healthcare provider if you develop reduced urination, swelling, unusual tiredness, or unexplained weight gain.
Liver Problems
Tell your healthcare provider if you have liver disease or reduced liver function.
Amlodipine may remain in the body longer in people with liver impairment. A lower starting dose or closer monitoring may therefore be needed.
Do not change your dose without medical advice.
High Potassium Levels
Olmesartan may increase potassium levels in the blood, a condition called hyperkalemia.
The risk may be higher in people with kidney disease or those taking potassium supplements, potassium-containing salt substitutes, or other medications that raise potassium levels.
Your healthcare provider may periodically check your potassium with blood tests.
Contact your healthcare provider if you experience unusual muscle weakness, numbness, tingling, or an irregular heartbeat.
Angioedema and Serious Allergic Reactions
Azor may rarely cause angioedema, which is sudden swelling beneath the skin. This reaction can become life-threatening if it affects the throat or airway.
Stop taking Azor and seek emergency medical care if you develop:
- Swelling of the face, lips, tongue, or throat
- Difficulty breathing or swallowing
- Hives
- Severe dizziness or fainting
Other allergic reactions may cause rash, itching, or swelling. Contact your healthcare provider if these symptoms occur.
Medication Interactions
Tell your healthcare provider and pharmacist about every prescription medication, over-the-counter medicine, vitamin, and supplement you use.
Azor may interact with medications such as:
- Diuretics
- Potassium supplements
- Potassium-containing salt substitutes
- Other blood pressure medications
- Nonsteroidal anti-inflammatory drugs, such as ibuprofen or naproxen
- Lithium
- Colesevelam
Some combinations may increase the risk of low blood pressure, kidney problems, high potassium levels, or other side effects.
Do not start, stop, or change another medication without first speaking with your healthcare provider.
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