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Fragmin is a prescription medication used to prevent blood clots, including deep vein thrombosis (DVT) and pulmonary embolism (PE), and to treat various forms of thrombosis, such as arterial thromboembolism, unstable angina, and non-Q wave myocardial infarction.
Fragmin’s primary component is Dalteparin, a low molecular weight heparin (LMWH). It belongs to the class of anticoagulants or blood thinners. It works by inhibiting specific clotting factors and enzymes responsible for blood clot formation.
Use and Dosage
The recommended administration method for Fragmin Pre-Filled Syringe involves injecting it into the fatty tissue on the right or left side of the stomach, thigh, or buttocks. If you need to self-administer the medication, your doctor or nurse will provide instructions on how to do so safely.
To take Fragmin, sit down or lie down before administering the shot. Wash your hands before and after using the syringe. For each injection, rotate the injection site to prevent excessive irritation at any one location. Follow the instructions provided in the package insert or by your healthcare professional.
The pre-filled syringe comes with a safety needle device and is for subcutaneous use only. Before injecting, check the syringe visually for any particulate matter or discoloration, and do not use it if present. Pinch a fatty fold of skin between your fingers, hold the syringe in your other hand, and firmly insert the needle at the injection site. Press down on the plunger to inject the medication, and then release the pressure on the plunger before removing the needle to avoid bleeding or medication leakage. Dispose of the used syringe and needle safely according to local regulations.
Do not use Fragmin Pre-Filled Syringe if you observe cloudiness, leakage, or the presence of particles in the solution. Similarly, avoid using the medication if there is any discernible change in the color of the solution. If you notice any of these issues, contact your healthcare provider for further guidance.
Common Side Effects of Fragmin Pre-Filled Syringe (Dalteparin Sodium):
- Chest pain
- Fainting, or swelling in your hands or feet
- Injection site reactions (pain, redness, bruising, swelling)
- Rapid breathing
- Shortness of breath
- Unusual tiredness or weakness
Serious Side Effects of Fragmin Pre-Filled Syringe (Dalteparin Sodium):
- Easy bruising or bleeding
- Pain, redness, irritation, bruising, or swelling where the medicine was injected
- Unusual or prolonged bleeding
- Unusual or easy bruising
- Purple or red pinpoints under your skin
- Dark urine
- Black or bloody stools
- Severe headache
- Trouble concentrating
- Vision changes
- Unusual dizziness
- Pale skin
- Shortness of breath
- Trouble breathing
- Rapid heart rate
- Coughing up blood or vomit that looks like coffee grounds
- Loss of movement in any part of your body
- Problems with speech vision or balance
- Sudden weakness
- Numbness, tingling, or muscle weakness (especially in your legs and feet)
Forms and Strength
Fragmin Pre-Filled Syringe (Dalteparin Sodium) is available in the following forms and strength:
Fragmin Pre-Filled Syringe: Injection
- Fragmin is a blood thinner and can increase the risk of bleeding.
- It should be used with caution in patients with a history of bleeding disorders, severe hypertension, or liver or kidney disease.
- Fragmin should be used with caution in patients with an increased risk of bleeding, such as those with uncontrolled high blood pressure, recent surgery, or pregnancy.
- Fragmin may interact with other medications, including over-the-counter medicines and herbal supplements. Consult with a doctor or pharmacist before taking any other medication while on Fragmin.
- Fragmin may cause allergic reactions and should be used with caution in patients with a history of hypersensitivity to heparin.
- Fragmin should not be used in patients with active major bleeding, thrombocytopenia (low platelet count), or a history of heparin-induced thrombocytopenia.
- Fragmin may increase the risk of spinal or epidural hematomas in patients undergoing spinal procedures or receiving epidural anesthesia.
- Fragmin should be used with caution in patients with an increased risk of falls or head injury.
- Fragmin should not be used in patients with uncontrolled high blood pressure, active or recent gastrointestinal bleeding, or a history of hemorrhagic stroke.
- Fragmin may cause side effects like bruising, pain, redness, or swelling at the injection site, which should be reported to a doctor if severe or persistent.
- Fragmin should be used with caution in elderly patients as they may be more prone to bleeding and other adverse reactions.
- Patients on Fragmin should avoid certain activities like contact sports or heavy lifting that may increase the risk of bleeding or injury.
- Fragmin should be used with caution in patients with a history of liver or kidney disease as it may affect the dose and frequency of Fragmin required.
- Patients on Fragmin should be closely monitored for signs of bleeding and other adverse reactions.
Frequently Asked Questions (FAQ)
Can I use Fragmin during pregnancy or while breastfeeding?
The use of Fragmin during pregnancy or while breastfeeding should be discussed with your healthcare provider. Fragmin may not be safe for all patients during these stages, and your provider will weigh the potential benefits and risks before deciding whether to prescribe the medication.
What should I do if I accidentally inject an air bubble along with the medication?
Small amounts of air or bubbles in the syringe are considered safe. However, if you inject a large air bubble or experience symptoms such as chest pain, shortness of breath, or difficulty breathing, seek immediate medical attention.
How often do I need to take Fragmin?
The dosing and frequency of Fragmin will depend on the condition being treated and the individual patient. Your healthcare provider will determine the correct dosage and frequency of administration.
It's important to purchase Fragmin Pre-Filled Syringe from verified Canadian pharmacy.