Indications
Fragmin is a prescription medication commonly used to prevent deep vein thrombosis (DVT), a type of blood clot that can cause serious complications such as pulmonary embolism. It can be used to treat unstable angina and related conditions.
Fragmin’s primary component is Dalteparin, a low molecular weight heparin (LMWH). It belongs to the class of anticoagulants or blood thinners. It works by inhibiting specific clotting factors and enzymes that are responsible for the formation of blood clots.
Use and Dosage
Fragmin Ampule is usually administered by subcutaneous injection, which means it is injected just under the skin without injecting it into a muscle. The dosage and duration of treatment will depend on your medical condition and your response to treatment, with weight being a factor in some cases.
If you are using Fragmin at home, learn all the preparation and usage instructions from your healthcare professional and the product package. To safely inject yourself, you should be in a lying or sitting position and visually inspect the solution for any particles or discoloration before using it. Do not use if either is present and do not mix Fragmin with any other medication in the same syringe.
Before injecting each dose, thoroughly clean the injection site with rubbing alcohol, and change the site each time to reduce skin damage. To minimize bruising, avoid rubbing the injection site after administering the shot.
If you are using Fragmin to prevent blood clots due to surgery, your doctor might direct you to begin taking it before or after the surgery and continue for a few days.
Side Effects
Common Side Effects of Fragmin Ampule (Dalteparin Sodium):
- Bleeding
- Bruising
- Chest pain
- Chills
- Dizziness
- Fainting
- Fever
- Headache
- Injection site reactions (pain, redness, bruising, swelling)
- Itching
- Nausea
- Rapid breathing
- Rash
- Shortness of breath
- Swelling in your hands or feet
- Unusual tiredness or weakness
- Vomiting
- Weakness
Serious Side Effects of Fragmin Ampule (Dalteparin Sodium):
- Bleeding from your gums or nose
- Blood clot around the spinal cord if you undergo a spinal tap or receive spinal anesthesia (epidural), prolonged bleeding
- Blood in your urine or stool
- Chest pain
- Confusion
- Coughing up blood
- Easy bruising
- Rapid heart rate
- Severe headache
- Shortness of breath
- Sudden vision changes
- Weakness or numbness on one side of your body
Forms and Strength
Fragmin Ampule (Dalteparin Sodium) is available in the following forms and strength:
Fragmin Ampule: Ampule
- 10000IU/mL
Cautions
- Fragmin should be used with caution in patients with bleeding disorders or a history of bleeding, as it can increase the risk of bleeding.
- Fragmin should be used with caution in patients with severe hypertension, bacterial endocarditis, severe liver or kidney disease, and stroke, as the risk of bleeding or other complications may be increased in these populations.
- Fragmin is contraindicated in patients with hypersensitivity to heparin or pork products, as it may cause allergic reactions.
- The safety and efficacy of Fragmin in children has not been established.
- Fragmin should not be administered intramuscularly.
- The multi-dose vial of Fragmin (25,000 IU/mL) contains benzyl alcohol, which may cause allergic reactions and should not be used in newborns or premature infants.
- Fragmin should be used with caution in patients with a history of heparin-induced thrombocytopenia (HIT), as it may cause a recurrence of this condition.
- Fragmin should be used with caution in patients who are undergoing anesthesia or surgery, as it may increase the risk of bleeding.
- Fragmin should be used with caution in patients who are using other anticoagulant medications, as it may increase the risk of bleeding.
- Fragmin should be used with caution in patients who have a low body weight, as they may be at a higher risk of bleeding.
- Fragmin should be used with caution in pregnant or breastfeeding women, as the drug can cross the placenta or pass into breast milk.
- Fragmin should be stored in a cool, dry place and should not be frozen or exposed to excessive heat or light.
Frequently Asked Questions (FAQ)
What should I do if I miss a dose of Fragmin Ampule?
If you miss a dose of Fragmin Ampule, contact your healthcare provider as soon as possible to determine the best course of action. Do not double up on doses to make up for a missed dose.
Is Fragmin Ampule safe for children?
The safety and efficacy of Fragmin Ampule in children has not been established. It should only be used in children under the guidance of a healthcare provider who is experienced in the use of anticoagulant medications in pediatric populations.
How long should I continue using Fragmin Ampule?
The duration of treatment with Fragmin Ampule will depend on your individual needs and condition. Your healthcare provider will determine the appropriate duration of treatment for you.
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