Epi Pen Auto Injector (Epinephrine)

Indications

EpiPen Auto-Injectors are medical devices used for the emergency treatment of severe allergic reactions (anaphylaxis) caused by allergens or exercise. The device contains epinephrine. Epinephrine is in a class of medications called alpha- and beta-adrenergic agonists (sympathomimetic agents).

Epinephrine works by relaxing the muscles in the airways and tightening the blood vessels. It also helps to constrict blood vessels and reduce swelling in the airways, making it easier to breathe.

Use and Dosage

Epinephrine injection can be administered via a prefilled automatic injection device or via vials. The solution can be injected subcutaneously (under the skin) or intramuscularly (into the muscle). Epinephrine injection should only be administered as directed by your doctor and should not be injected more or less frequently than prescribed.

Talk to your doctor about these symptoms and know how to recognize signs of a serious allergic reaction. Keep your automatic injection device with you or available so you can quickly administer epinephrine if needed. Be sure to check the expiration date on the device and replace it when needed. Additionally, periodically inspect the solution in the device and if it is discolored or has particles, contact your doctor for a new injection device. Epinephrine injection can help treat serious allergic reactions, but it should not be a substitute for medical treatment.

If you inject epinephrine, seek emergency medical treatment immediately. Wait quietly for medical attention. Most automatic injection devices have enough solution for one dose. If your symptoms persist or return after the first injection, your doctor may advise you to use a second dose with a new device. Make sure you know how to administer the second dose and when to do so. Only healthcare providers should give more than two injections for a single allergic episode. Inject epinephrine only in the middle of the outer side of the thigh and through clothing, if necessary, in an emergency.

If administering to a child, ensure their leg is firmly held in place. Do not inject epinephrine into other parts such as fingers, hands, feet, or buttocks, or into a vein. Never cover or touch the needle area of the injection device, as this can result in accidental injection. Seek emergency medical attention if epinephrine is accidentally injected in these areas. After injecting, some solution will remain in the device. This is normal, and you should not use extra liquid. Dispose of the remaining liquid and device safely. Take the used device to the emergency room or ask your healthcare provider how to properly dispose of it.

Side Effects

Common Side Effects of Epi Pen Auto Injector (Epinephrine):

• Anxiety
• Breathing problems
• Dizziness
• Fast or pounding heartbeats
• Fearfulness
• Nausea and vomiting
• Nervousness
• Pale skin
• Sweating
• Throbbing headache
• Tremors
• Weakness

Forms and Strength

Epi Pen Auto Injector (Epinephrine) is available in the following forms and strength:

Epi Pen Auto Injector: Injection

• 0.3 mg

Cautions

• Keep the EpiPen Auto Injector at room temperature and protect it from light and extreme temperatures.
• Keep the EpiPen Auto Injector out of the reach of children.
• Be aware of the expiration date and replace the EpiPen Auto Injector before it expires.
• Use the EpiPen Auto Injector as directed by your healthcare professional and only for emergencies.
• Do not use the EpiPen Auto Injector if it appears to be discolored or contains particles.
• Seek immediate medical attention after using the EpiPen Auto Injector, even if symptoms improve.
• Keep the EpiPen Auto Injector at room temperature and away from light and extreme temperatures.
• Keep the EpiPen Auto Injector out of the reach of children and individuals who may accidentally use it.
• Know the expiration date of the EpiPen Auto Injector and replace it before it expires.
• Notify your healthcare provider of any medical conditions you may have, as they may exacerbate side effects of the EpiPen Auto Injector.
• Be aware of potential side effects, including increased heart rate, headache, dizziness, and anxiety, and seek medical attention if they persist or worsen.
• Notify your healthcare provider of all medications you may be taking, as they may interact with the EpiPen Auto Injector.
• Store the EpiPen Auto Injector in an easily accessible location in case of an emergency.

Frequently Asked Questions (FAQ)

Can anyone use an EpiPen Auto-Injector?

EpiPens can be used by anyone who has been prescribed the device by a healthcare provider.

Can an EpiPen Auto-Injector be reused?

No, EpiPens are designed for a single use only. Each device contains a single dose of epinephrine and should be disposed of appropriately after use.

How many EpiPens should I carry with me?

If you have been prescribed an EpiPen, carry two with you in case you need a second dose.

How often should I replace my EpiPen Auto-Injector?

EpiPens have an expiration date and should be replaced before they expire to ensure their effectiveness. Check the expiration date on your EpiPen regularly and replace it, as necessary.

Resources

• https://medlineplus.gov/druginfo/meds/a603002.html
• https://www.rxlist.com/epipen-drug.htm
• https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/019430s053lbl.pdf
• https://www.webmd.com/drugs/2/drug-20017/epipen-injection/details
• https://www.epipen.com/hcp/about-epipen-and-generic.aspx
• https://www.nationwidechildrens.org/family-resources-education/health-wellness-and-safety-resources/helping-hands/epipen