Depo Provera Injection (Medroxyprogesterone)

Indications

Depo-Provera is an injectable contraceptive that contains the hormone medroxyprogesterone acetate. It is given by injection into the arm or buttocks every 12 to 13 weeks, depending on the prescription and individual factors. Depo-Provera works to prevent pregnancy by stopping ovulation and thickening the mucus in the cervix, making it difficult for sperm to reach the egg.

Use and Dosage

Depo Provera is a form of birth control that is administered by injection into a muscle in either the upper arm or buttock - as directed by your doctor - usually once every 3 months. Ensure that you are not pregnant; thus, the first injection is typically given during the first five days of your menstrual period.

If you have just given birth or experienced a pregnancy loss or abortion after the first 3 months of pregnancy, consult with your doctor to determine the best time to start using this type of birth control.

If you are administering the Depo Provera injection at home, it is crucial to follow all preparation and usage instructions provided by your healthcare professional. You should visually inspect the injection for particles or discoloration before using it and should not use the liquid if either is present. Additionally, learn how to store and discard medical supplies safely.

To obtain the maximum benefit of Depo Provera, use it regularly. If more than 13 weeks pass between injections, there is a risk of becoming pregnant. It is recommended to use a non-hormonal form of birth control (such as condoms, a diaphragm, or spermicide) until you can receive your next injection. Your doctor may advise you to undergo a pregnancy test before your next injection.

Side Effects

Common Side Effects of Depo Provera Injection (Medroxyprogesterone):

• Acne
• Bloating
• Breast tenderness
• Changes in appetite
• Changes in menstrual periods
• Decrease in breast size
• Decreased sex drive
• Depression
• Dizziness
• Drowsiness
• Excessive growth of facial and body hair
• Hair loss
• Headaches
• Hot flashes
• Injection site reactions (irritation pain skin changes or a hard lump)
• Irregular menstrual periods or no periods at all, which is a safe benefit of the shot
• Irritability
• Joint pain
• Nausea
• Nervousness
• Osteoporosis
• Stomach cramping or pain
• Tiredness
• Weight gain

Serious Side Effects of Depo Provera Injection (Medroxyprogesterone):

• Bone pain
• Changes in sexual interest or ability
• Dark urine
• Mental/mood changes (such as new or worsening depression)
• Persistent nausea or vomiting
• Seizures
• Severe stomach/abdominal/pelvic pain
• Swelling of the ankles or feet
• Unusual changes in vaginal bleeding (such as continuous spotting sudden heavy bleeding)
• Unusual weakness or tiredness
• Yellowing eyes or skin

Forms and Strength

Depo Provera Injection (Medroxyprogesterone) is available in the following forms and strength:

Depo Provera Injection: Vial

• 150mg/mL

Cautions

• Loss of bone density: Depo-Provera may cause a loss of bone density, especially in younger women or those who use Depo-Provera for a long time. This can increase the risk of osteoporosis and bone fractures.
• Increased risk of blood clots: Women who use Depo-Provera may be at a slightly increased risk of developing blood clots, especially if they have other risk factors for blood clots such as smoking, obesity, or a personal history of blood clots.
• Delay in return to fertility: After stopping the use of Depo-Provera, it may take several months for fertility to return to normal. This can be a concern for women who want to become pregnant soon after stopping Depo-Provera.
• Side effects: Depo-Provera can cause side effects, such as irregular menstrual bleeding, weight gain, headaches, and mood changes.
• Potential interactions with other medications: Some medications may interact with Depo-Provera and reduce its effectiveness or increase the risk of side effects.
• Potential delay in return of fertility: After stopping the use of Depo-Provera Injection, it may take several months for menstrual cycles and fertility to return to normal.
• Higher risk for sexually transmitted infections: Due to the lack of menstrual bleeding while using Depo-Provera, there may be a potential for increased risk of sexually transmitted infections if safe sex practices are not followed.
• Breastfeeding considerations: Women who are considering Depo-Provera use while breastfeeding should discuss potential concerns with their healthcare provider.
• Potential for allergic reactions: Some women may experience allergic reactions to Depo-Provera, which may include hives, difficulty breathing, or swelling of the face, lips, tongue, or throat.

Frequently Asked Questions (FAQ)

How long does Depo last?

Depo Provera is a hormone used for contraception. It is given by injection and its effects will last for three months at a time. It is similar to progesterone, which is one of the two main hormones made by a woman's ovaries during her normal cycle.

Can Depo Provera injection be used while breastfeeding?

Yes, Depo Provera injection can be used safely while breastfeeding.

How long after Depo can I get pregnant?

Hopefully, your fertility will come back within three or six months after your last shot. This is how it should work, and many women do get pregnant within 8 to 10 months of their last Depo-Provera shot. However, in some cases, it can take longer.

What happens if I miss a Depo Provera injection?

If you miss an injection, there is a risk of becoming pregnant. It is crucial to schedule your next injection as soon as possible, and until then, use a non-hormonal form of birth control.

Resources

• https://www.drugs.com/depo-provera.html
• https://www.rxlist.com/depo-provera-side-effects-drug-center.htm
• https://www.accessdata.fda.gov/drugsatfda_docs/label/2003/20246scs019_depo-provera_lbl.pdf
• https://my.clevelandclinic.org/health/drugs/4086-depo-provera-birth-control-shot
• https://www.verywellhealth.com/common-depo-provera-side-effects-906709
• https://www.webmd.com/drugs/2/drug-12156/depo-provera-intramuscular/details