Alesse 21 day (Levonorgestrel/Ethinyl Estradiol)

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Alesse 21 day Brand
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Levonorgestrel/Ethinyl Estradiol (Generic alternate to Alesse 21 day) Generic

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Table of contents:

Alesse 21-day is a birth control pill used to prevent pregnancy by suppressing ovulation, thickening cervical mucus to block sperm from reaching the egg, and thinning the lining of the uterus to make it less suitable for implantation.

Alesse contains levonorgestrel and ethinyl estradiol. Levonorgestrel - ethinyl estradiol is a progestin (levonorgestrel) and estrogen (ethinyl estradiol) combination birth control pill used to prevent pregnancy.

Use and Dosage

Alesse 21-day is taken orally, once a day, at the same time every day for 21 consecutive days, followed by 7 days without pills. Take the medication with food or at bedtime to prevent stomach upset.

Alesse 21-day comes in a pack of pills. Each pack contains 21 active pink pills (with hormones). Take 1 tablet daily for 21 days, then take no pills for 7 days, and then begin the next pack. Take the pills in the correct order and at the same time every day to maximize effectiveness in preventing pregnancy. Always follow your doctor's instructions on when to start taking Alesse and use an additional form of contraception, such as condoms, during the first week of taking the medication to ensure protection against pregnancy.

If you miss a pill, take it as soon as you remember, even if it means taking two pills in one day.

Side Effects

Common Side Effects of Alesse 21-day (levonorgestrel/ethinyl estradiol):

  • Acne
  • Breast pain, tenderness, or swelling
  • Contact lens discomfort
  • Gain or loss of body or facial hair
  • Growth of fibroids
  • Headache
  • Increased or decreased interest in sexual activity
  • Nausea
  • Skin rash
  • Vomiting
  • Weight changes

Serious Side Effects of Alesse 21-day (levonorgestrel/ethinyl estradiol):

  • Breakthrough bleeding or spotting
  • Breast lump(s)
  • Brown, blotchy spots on exposed skin
  • Changes in sleep
  • Changes in weight
  • Dark urine
  • Decreased interest in activities
  • Diarrhea
  • Increased blood pressure
  • Lack of period
  • Loss of appetite
  • Low back or flank pain
  • Lumps in the abdomen with pain, nausea, or vomiting
  • Pain when urinating
  • Pain, or tenderness in upper abdominal area
  • Pale stools
  • Poor concentration
  • Prolonged bleeding during periods
  • Severe headaches
  • Swelling
  • Thick, white, or curd-like discharge
  • Thoughts of suicide
  • Urinating more often than usual
  • Vaginal infection
  • Vaginal itching or irritation
  • Weight loss
  • Yellowing of the skin or whites of the eyes

Forms and Strength

Alesse 21-day (levonorgestrel/ethinyl estradiol) is available in the following forms and strength:

Alesse 21-day: Packs

  • 0.1/0.02mg


  • Patients with certain medical conditions, such as a history of blood clots, heart attack, stroke, angina, liver disease, breast cancer, or uncontrolled high blood pressure should use Alesse with caution.
  • Smoking tobacco while taking Alesse may increase the risk of serious cardiovascular side effects.
  • Alesse should not be used as a form of emergency contraception or by women who are already pregnant.
  • Women who are breastfeeding should consult their healthcare provider before taking Alesse.
  • Alesse may interact with other medications, such as antibiotics, antifungal drugs, and anti-seizure medications. Inform the healthcare provider of all medications currently being taken to avoid potential drug interactions.
  • Alesse may cause severe allergic reactions in some patients. Signs and symptoms to watch for include difficulty breathing, hives, and swelling of the face, lips, tongue, or throat. If an allergic reaction is suspected, medical attention should be sought immediately.
  • Alesse may increase the risk of a rare but serious brain condition called intracranial hypertension, which can cause headaches, vision changes, and in severe cases, permanent vision loss. Patients who experience these symptoms while taking Alesse should seek medical attention immediately.
  • Alesse may increase the risk of developing blood clots, which can lead to serious or life-threatening complications such as stroke, heart attack, or pulmonary embolism. Women with a personal or family history of blood clots or certain medical conditions that increase the risk of blood clots (such as thrombophilia) should use Alesse with caution and discuss the risks versus benefits with their healthcare provider.
  • Alesse should be used with caution in women who have a history of depression or other psychiatric disorders, as it may worsen these conditions or increase the risk of depressive symptoms.
  • Alesse may affect glucose tolerance and may worsen diabetes in some women. Women with diabetes should monitor their blood sugar levels closely while taking Alesse and report any changes to their healthcare provider.
  • Alesse may cause changes in menstrual bleeding patterns, including irregular bleeding, spotting, or prolonged bleeding, especially during the first few months of use. These changes may require medical attention if they persist or are severe.

Frequently Asked Questions (FAQ)

How effective is Alesse 21-day in preventing pregnancy?

Alesse 21-day is a highly effective form of birth control when taken correctly and consistently. It has a failure rate of less than 1% with perfect use and up to 9% with typical use.

Can Alesse 21-day (levonorgestrel/ethinyl estradiol) be used to treat acne?

Alesse 21-day is not approved by the FDA for the treatment of acne, but it may help improve acne in some women due to its ability to regulate hormone levels.

Can Alesse-21-day (levonorgestrel/ethinyl estradiol) cause mood swings?

Mood changes, including depression or anxiety, are possible side effects of Alesse 21-day. They are more likely to occur in women with a history of mental health problems or those who are sensitive to hormonal changes.

Is a prescription required to obtain Alesse 21-day (levonorgestrel/ethinyl estradiol)?

Yes, Alesse 21-day is a prescription-only medication and must be obtained through a healthcare provider or a licensed pharmacy.


It's important to purchase Alesse 21 day from verified Canadian pharmacy.

Additional information

Generic name:

Levonorgestrel/Ethinyl Estradiol





Quantities Available:

1, 3


Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Alesse 21 day (Levonorgestrel/Ethinyl Estradiol). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Alesse 21 day (Levonorgestrel/Ethinyl Estradiol).