Skip to main content

Natazia (estradiol valerate and estradiol valerate/dienogest) Shopper Approved

Prescription Prescription Required FormationFormulation: Tablet

Natazia

(Brand Option)

Select the prescribed dosage

Select the quantity to see the price.

  *  
Prescription Prescription Required FormationFormulation: Tablet

estradiol valerate and estradiol valerate/dienogest

We don't sell this generic-version medication.

Select the quantity to see the price.

  *  
delivery

* This price includes a dispensing fee, medical review fee, and packing fee.

delivery

Shipped and delivered directly to your doorstep

Natazia is a prescription combination oral contraceptive that contains estradiol valerate and dienogest.

It is used to prevent pregnancy and may also be prescribed to treat heavy menstrual bleeding in women who choose to use an oral contraceptive for birth control.

What Is Natazia Used For?

Natazia is mainly used for:

  • Preventing pregnancy
  • Treating heavy menstrual bleeding in women without an underlying structural or medical cause who also want oral contraception

Your healthcare provider will determine whether Natazia is appropriate based on your medical history, bleeding pattern, and contraceptive needs.

How Does Natazia Prevent Pregnancy?

Natazia works mainly by preventing ovulation, which means it helps stop the ovaries from releasing an egg.

Without ovulation, there is no egg available for fertilization.

Natazia also thickens cervical mucus, which makes it more difficult for sperm to travel through the cervix.

How Does Natazia Affect the Uterine Lining?

Natazia also changes the lining of the uterus, called the endometrium.

These changes help make the reproductive environment less favorable for pregnancy and also contribute to its effects on menstrual bleeding.

How Does Natazia Help With Heavy Menstrual Bleeding?

Natazia may reduce the amount of menstrual bleeding in women who do not have another identifiable medical cause for their heavy periods.

Its combination of estrogen and progestin helps regulate hormonal changes throughout the menstrual cycle and can reduce the buildup and shedding of the uterine lining.

This may result in lighter and more manageable periods over time.

What Type of Birth Control Is Natazia?

Natazia belongs to a class of medications called combination oral contraceptives, or COCs.

Unlike some birth control pills that contain ethinyl estradiol, Natazia contains estradiol valerate along with the progestin dienogest.

The tablets are taken in a specific sequence during each 28-day pack because the hormone amounts change throughout the cycle.

Does Natazia Protect Against Sexually Transmitted Infections?

No. Natazia does not protect against HIV or other sexually transmitted infections.

Barrier protection, such as condoms, may still be needed to reduce the risk of sexually transmitted infections.

Does Natazia Cure Heavy Menstrual Bleeding?

Natazia can help control heavy menstrual bleeding while it is being used, but it does not necessarily cure the underlying tendency to have heavy periods.

If heavy bleeding continues, becomes worse, or returns after stopping treatment, your healthcare provider may recommend further evaluation.

Natazia is taken by mouth once daily.

Choose a time that is easy to remember and take your tablet at approximately the same time every day. Taking it consistently helps maintain reliable contraceptive protection.

Take the Tablets in the Correct Order

Natazia comes in a 28-day pack with tablets that contain different amounts of hormones.

Take the tablets in the exact order shown on the package. Do not skip ahead or rearrange the tablets, because the hormone dose changes throughout the cycle.

Start a new pack the day after you finish the previous pack, without taking a break between packs.

Can Natazia Be Taken With Food?

Natazia may be taken with or without food.

If it causes nausea or stomach upset, taking it with or after a meal may make it easier to tolerate.

When Should I Start Natazia?

If you are starting Natazia and are not switching directly from another hormonal contraceptive, treatment is generally started on the first day of your menstrual period.

Follow the specific starting instructions provided by your healthcare provider or in the package information, especially if you are switching from another birth control method.

Use Backup Birth Control When Starting

When starting Natazia, use a non-hormonal backup method of contraception, such as condoms, for the first 9 days unless your healthcare provider tells you otherwise.

This gives the medication enough time to provide reliable pregnancy protection during the first treatment cycle.

Take Natazia at the Same Time Each Day

Try not to take your tablet more than 12 hours later than your usual time.

Taking pills late or missing doses can reduce contraceptive protection, especially because the hormone amounts vary throughout the Natazia pack.

Setting a daily reminder can help you stay on schedule.

What If I Miss a Pill?

Missed-pill instructions for Natazia depend on which tablet in the pack was missed and how many pills were missed.

Do not automatically follow the missed-pill directions for other birth control pills, because Natazia uses a multiphasic dosing schedule.

Check the package instructions or contact your healthcare provider or pharmacist for guidance. You may need to use backup contraception for a period of time.

Do Not Take More Than Directed

Take only one scheduled tablet each day unless the specific missed-dose instructions tell you otherwise.

Do not take extra tablets on your own to improve contraceptive protection.

If you miss several tablets, have vomiting or severe diarrhea, or are unsure whether you are still protected against pregnancy, contact your healthcare provider or pharmacist and use a non-hormonal backup method until you receive guidance.

Common Side Effects of Natazia (Estradiol Valerate/Dienogest):

  • Acne
  • Breast pain, discomfort, or tenderness
  • Headache
  • Irregular vaginal bleeding
  • Mood changes
  • Nausea or vomiting
  • Weight gain

Serious Side Effects of Natazia (Estradiol Valerate/Dienogest):

  • Chest pain
  • Cough
  • Dizziness
  • Fluid buildup
  • Leg cramp
  • Muscle tightness
  • Racing heart
  • Rash
  • Stomach pain
  • Swelling
  • Tiredness
  • Trouble breathing
  • Vaginal yeast infection
  • Yellowing of the skin or the whites of the eyes

Natazia (estradiol valerate/dienogest) is available in the following forms and strength:

Natazia: Tablet

  • 3 mg, 1 mg, and 2 mg/2 mg, 2 mg/3 mg

Natazia is a combined oral contraceptive that can increase the risk of blood clots and other serious cardiovascular problems.

Before starting Natazia, tell your healthcare provider about your medical conditions, smoking status, family medical history, and all medications and supplements you take.

Blood Clots, Stroke, and Heart Attack

Natazia can increase the risk of blood clots.

Blood clots may develop in the legs as deep vein thrombosis (DVT), travel to the lungs and cause a pulmonary embolism (PE), or contribute to serious cardiovascular events such as a stroke or heart attack.

Seek immediate medical attention if you develop:

  • Sudden chest pain
  • Shortness of breath
  • Coughing up blood
  • Sudden swelling or pain in one leg
  • Sudden weakness or numbness
  • Difficulty speaking
  • Sudden severe headache
  • Sudden vision changes

Smoking and Natazia

Smoking significantly increases the risk of serious cardiovascular side effects from combined oral contraceptives.

The risk is especially high in women 35 years of age and older who smoke. Natazia should generally not be used in this group.

If you smoke, talk to your healthcare provider about safer birth control options.

High Blood Pressure

Natazia and other combined oral contraceptives can increase blood pressure.

Your healthcare provider may check your blood pressure before and during treatment.

Tell your provider if your blood pressure becomes consistently elevated. Natazia may not be appropriate for people with uncontrolled hypertension.

Drug Interactions

Certain medications can cause the hormones in Natazia to be broken down more quickly.

This may reduce the effectiveness of Natazia and increase the risk of pregnancy.

Tell your healthcare provider about all prescription medications, over-the-counter drugs, vitamins, supplements, and herbal products you take.

You may need to use an additional non-hormonal contraceptive method during treatment with certain interacting medications and for a period afterward.

Breast Cancer

Natazia should not be used in people who currently have, or have had, certain hormone-sensitive cancers such as breast cancer.

Some breast cancers can grow in response to estrogen or other hormones.

Tell your healthcare provider about any personal or family history of breast cancer before starting Natazia.

Liver Problems

Natazia can rarely cause liver problems and should not be used in people with certain serious liver conditions or liver tumors.

Contact your healthcare provider if you develop symptoms such as:

  • Yellowing of the skin or eyes
  • Dark urine
  • Persistent nausea
  • Severe upper abdominal pain
  • Unusual tiredness

Diabetes and Blood Sugar

Natazia may affect glucose metabolism in some people.

If you have diabetes, your healthcare provider may recommend monitoring your blood sugar more closely after starting treatment.

Report significant or unexplained changes in your blood glucose levels.

High Triglycerides

Combined oral contraceptives may increase triglyceride levels in some patients.

People who already have very high triglycerides may have an increased risk of pancreatitis.

Tell your healthcare provider if you have a history of elevated triglycerides or pancreatitis.

Chloasma

Natazia may contribute to chloasma, which causes brown or darker patches of skin, commonly on the face.

If you have developed chloasma during pregnancy or while using hormonal contraceptives in the past, limit unnecessary exposure to sunlight and ultraviolet light.

Using sun protection may help prevent the pigmentation from becoming more noticeable.

Hereditary Angioedema

Estrogen-containing contraceptives such as Natazia may trigger or worsen symptoms in people with hereditary angioedema.

Tell your healthcare provider if you have a history of this condition before starting treatment.

Regular Medical Follow-Up

Regular checkups are important while taking Natazia.

Your healthcare provider may monitor your blood pressure and review changes in your health, medications, blood sugar, triglycerides, or other cardiovascular risk factors.

Contact your healthcare provider promptly if you develop new or worsening symptoms, and seek emergency care for possible signs of a blood clot, stroke, or heart attack.

Can Natazia Be Used to Treat Heavy Menstrual Bleeding?

Yes. Natazia can be used to treat heavy menstrual bleeding in women who also want to use an oral contraceptive for birth control. It is intended for women whose heavy bleeding is not caused by another underlying medical condition. If heavy bleeding continues or becomes worse while taking Natazia, contact your healthcare provider for further evaluation.

How Effective Is Natazia at Preventing Pregnancy?

Natazia is highly effective when taken correctly and consistently. With perfect use, combination oral contraceptives are more than 99% effective at preventing pregnancy. However, real-world effectiveness is lower because pills may sometimes be missed or taken late. Taking Natazia at the same time every day and following the correct tablet order in the pack helps maintain contraceptive protection.

How Quickly Does Natazia Start Working?

When Natazia is started on the first day of your menstrual period, use a non-hormonal backup method of contraception, such as condoms, for the first 9 days unless your healthcare provider tells you otherwise. If you start Natazia at another time or are switching from another contraceptive method, follow the specific instructions provided by your healthcare provider or in the package information. Because Natazia has a unique multiphasic dosing schedule, its backup contraception instructions differ from those of some other birth control pills.

Can Natazia Cause Weight Gain?

Some people may notice changes in weight while taking Natazia, but weight gain does not occur in everyone. Weight changes may also be influenced by fluid retention, diet, activity level, and other factors. If you experience significant or unexpected weight gain, swelling, or other concerning changes, talk to your healthcare provider.

REVIEWS

Additional Information Book
Generic name:

estradiol valerate and estradiol valerate/dienogest

Formulation:

Tablet

Strength(s):

3mg, 1mg and 2mg/2mg, 2mg/3mg

Quantities Available:

84

Why customers love Online Pharmacies Canada

Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.

Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.

How to Order

How much Natazia can I order at once from a Canadian pharmacy?

When ordering Natazia (estradiol valerate and estradiol valerate/dienogest) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time. This is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.

Here’s what you need to know:

Dosage and Quantity: Natazia is taken once daily according to a 28-day cycle. Each pack contains 28 tablets. For a 90-day supply, this means you would order 3 packs (90 days / 28 days per pack).

Do you sell estradiol valerate and estradiol valerate/dienogest?

No, we do not sell estradiol valerate and estradiol valerate/dienogest separately. However, you can still enjoy low prices on Natazia, which contains estradiol valerate and estradiol valerate/dienogest as an active ingredient. You will need a valid prescription from your healthcare provider to purchase Natazia. We require this prescription to dispense the medication, and you can submit it by mail, fax, or upload through your online account.

Do you offer shipping of Natazia (estradiol valerate and estradiol valerate/dienogest) to the United States?

Yes, we ship Natazia (estradiol valerate and estradiol valerate/dienogest) to both the United States and Puerto Rico.

Discover Our Users' Stories!

Watch how Online Pharmacies Canada is helping customers save money on their medications.

Online Pharmacies Canada Customer Testimonial #4
Online Pharmacies Canada Customer Testimonial #1
Online Pharmacies Canada - Customer Testimonial #2

Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Natazia (estradiol valerate and estradiol valerate/dienogest). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Natazia (estradiol valerate and estradiol valerate/dienogest).