Cortone (Cortisone Acetate)

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Cortisone Acetate (Generic alternate to Cortone) Generic
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Drug Description


Cortone (generically known as Cortisone Acetate) is a prescription medicine used to treat various conditions, including allergies, skin problems, arthritis, and ulcerative colitis. Cortisone Acetate is a synthetic version of cortisol, a hormone naturally produced by the adrenal glands. Cortisone is metabolized by the liver into cortisol, and the cortisol then binds to specific receptors in the cells of the body, leading to a decrease in inflammation in the affected tissues.

Cortisone Acetate is a steroid hormone that works by decreasing inflammation and suppressing the immune system. By suppressing the immune system, it helps to reduce the body’s response to various triggers that can cause inflammation, such as allergens or irritants.

Uses and Dosage

Cortisone Acetate tablets are typically taken by mouth with food or milk to prevent stomach upset. It is usually taken once or twice daily for several days to several weeks, depending on the condition being treated. Take the tablet with a full glass of water (8 ounces/240 milliliters) unless your doctor directs you otherwise. If you are taking Cortisone Acetate once daily, take it in the morning before 9 AM. If you are taking Cortisone Acetate every other day or on another schedule besides a daily one, it may be helpful to mark your calendar with a reminder.

The dosage and length of treatment for Cortisone Acetate tablets are determined based on your medical condition and response to therapy. To get the most benefit from the medication, take the tablets regularly. You should take Cortisone Acetate at the same time(s) each day to help you remember. Even if you feel well, keep taking the medication as prescribed by your doctor. Follow the dosing schedule carefully and take the medication exactly as prescribed.

Do not stop taking Cortisone Acetate tablets without first consulting with your doctor. Stopping the medication suddenly may cause some conditions to become worse, and your dose may need to be gradually decreased.

Side effect

Common Side Effects of Cortone (Cortisone Acetate):

  • Acne
  • Bloating
  • Bruising or discoloration
  • Changes in the shape or location of body fat (especially in your arms legs face neck breasts and waist)
  • Dizziness
  • Dry skin
  • Headache
  • Increased sweating
  • Mood changes
  • Nausea
  • Sleep problems (insomnia)
  • Slow wound healing
  • Spinning sensation
  • Stomach pain
  • Thinning skin

Serious Side Effects of Cortone (Cortisone Acetate):

  • Anxiety
  • Bloody or tarry stools
  • Blurred vision
  • Buzzing in your ears
  • Chest pain and
  • Confusion
  • Coughing up blood
  • Difficulty breathing
  • Extreme thirst
  • Fast heart rate
  • Hives
  • Increased urination
  • Leg discomfort
  • Limp feeling
  • Muscle weakness
  • Nausea
  • Rapid weight gain
  • Seizure
  • Severe depression
  • Severe headache
  • Severe pain in your upper stomach spreading to your back
  • Shortness of breath
  • Swelling
  • Swelling of your face lips tongue or throat
  • Uneven heart rate
  • Uneven heartbeats
  • Unusual thoughts of behavior
  • Vision problems
  • Vomiting

Form and Strength

Cortone (Cortisone Acetate) is available in the following forms and strength:

Cortisone Acetate: Tablet

  • 25 mg


  • Cortisone Acetate should not be taken by pregnant or breastfeeding women without a doctor’s approval.
  • Cortisone Acetate is not recommended for use in children unless prescribed by a doctor.
  • Cortisone Acetate may interact with other medicines, so patients should inform their doctor of any other medications they are taking before starting treatment.
  • Patients with certain health conditions, such as liver disease or high blood pressure, may need to be monitored more closely while taking Cortisone Acetate.
  • Cortisone Acetate may lower the immune system, making it harder for the body to fight infections.
  • Long-term use of Cortisone Acetate may increase the risk of developing certain health conditions such as osteoporosis, cataracts, and diabetes.
  • Patients should avoid live virus vaccines while taking Cortisone Acetate as it may make the vaccine less effective.
  • Cortisone Acetate may cause mood changes, including irritability, anxiety, or depression.
  • Patients should not stop taking Cortisone Acetate suddenly as this may cause withdrawal symptoms.
  • Cortisone Acetate may mask the symptoms of certain infections, making them harder to diagnose.

Frequently Asked Questions (FAQ)

How long does it take for Cortisone Acetate to work?

The amount of time it takes for Cortisone Acetate to work can vary depending on the condition being treated and the form of the medication. Typically, patients start to see improvement within a few days to a week.

Can Cortisone Acetate be used during pregnancy or while breastfeeding?

Discuss the safety of Cortisone Acetate use during pregnancy or while breastfeeding with your healthcare provider. The use of Cortisone Acetate during pregnancy and breastfeeding should be weighed against the potential risks and benefits.

Is it safe to stop taking Cortisone Acetate suddenly?

No, do not stop taking Cortisone Acetate suddenly. Stopping Cortisone Acetate suddenly can cause withdrawal symptoms and have other negative effects. Follow your healthcare provider’s instructions for gradually tapering off the medication.

Can Cortisone Acetate cause problems with the adrenal glands?

Prolonged use of Cortisone Acetate can cause problems with the adrenal glands. Follow your healthcare provider’s instructions for taking Cortisone Acetate and to report any symptoms of adrenal gland problems, such as fatigue or weakness.

Can Cortisone Acetate cause side effects on the skin?

Yes, Cortisone Acetate can cause side effects on the skin, such as thinning or discoloration of the skin. Discuss any new or worsening skin symptoms with your healthcare provider.


Additional information

Generic name:

Cortisone Acetate





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