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Imuran (Azathioprine) Shopper Approved

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Imuran

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Prescription Prescription Required FormationFormulation: Tablet

Azathioprine

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Imuran (active ingredient: azathioprine) is a prescription medication used to suppress the immune system. It is prescribed to help prevent the immune system from attacking healthy tissues or a transplanted organ.

Imuran is approved for the treatment of the following conditions:

Rheumatoid Arthritis

Imuran is used to treat active rheumatoid arthritis (RA) in adults, particularly when other treatments have not provided adequate symptom relief.

Rheumatoid arthritis is an autoimmune disease in which the immune system mistakenly attacks the lining of the joints, causing inflammation and damage.

Common symptoms of rheumatoid arthritis include:

  • Joint pain and tenderness.
  • Swelling in the joints.
  • Morning stiffness.
  • Fatigue.
  • Reduced range of motion.

Imuran helps reduce inflammation and may improve joint pain, swelling, stiffness, and overall physical function.

Prevention of Kidney Transplant Rejection

Imuran is also used to help prevent rejection after a kidney transplant.

After a transplant, the immune system recognizes the new kidney as foreign and may try to attack it. This is known as organ rejection.

Imuran helps suppress the immune response, reducing the risk of transplant rejection and helping the transplanted kidney function properly. It is often used together with other immunosuppressant medications as part of a long-term treatment plan.

How Does Imuran Work?

Imuran belongs to a group of medications called immunosuppressants.

It works by reducing the activity of the immune system, slowing the production of certain immune cells that contribute to inflammation and immune attacks.

By suppressing the immune response, Imuran helps:

  • Reduce inflammation and joint damage in rheumatoid arthritis.
  • Relieve symptoms such as pain, swelling, and stiffness.
  • Prevent the immune system from attacking a transplanted kidney.
  • Improve long-term transplant success.

Because Imuran weakens the immune system, it may also increase the risk of infections. Your healthcare provider will monitor you closely with regular blood tests throughout treatment to help ensure the medication remains safe and effective.

Imuran does not cure rheumatoid arthritis or eliminate the need for lifelong treatment after a kidney transplant. However, when taken consistently as prescribed, it can help control disease activity, prevent transplant rejection, and improve long-term outcomes.

Imuran is available as an oral tablet that should be taken exactly as prescribed by your healthcare provider.

It is usually taken once or twice daily. Taking Imuran with food may help reduce stomach upset.

Swallow the tablets whole with a glass of water. Do not crush, chew, or split the tablets, as this may release the medication as dust or powder, which should be avoided because it can be harmful if inhaled or comes into contact with your skin.

Take Imuran at the same time each day to help maintain a consistent level of medication in your body. Continue taking the medication for as long as your healthcare provider prescribes, even if you begin to feel better.

Your healthcare provider will determine the dose that is right for you based on your medical condition, body weight, and response to treatment.

Recommended Dosages

Kidney Transplant Rejection Prevention

For the prevention of kidney transplant rejection, the usual dose is:

  • 1 to 3 mg/kg of body weight per day, typically 50 mg to 150 mg daily.

Your healthcare provider may adjust your dose based on your response to treatment and your blood test results.

Rheumatoid Arthritis

For the treatment of rheumatoid arthritis, the usual starting dose is:

  • 1 mg/kg of body weight per day, taken as a single daily dose or divided into two doses daily.

Your healthcare provider may gradually adjust your dose depending on how well your symptoms improve and whether you experience any side effects.

Important Tips

  • Take Imuran with food to help reduce stomach upset.
  • Swallow the tablets whole with water.
  • Do not crush, chew, or split the tablets.
  • Take your medication at the same time each day.
  • Do not stop taking Imuran without first consulting your healthcare provider.
  • Keep all scheduled appointments for blood tests and follow-up visits, as your healthcare provider will monitor your blood cell counts and liver function regularly to help ensure the medication remains safe and effective.

Common Side Effects of Imuran (Azathioprine):

  • Dizziness
  • Drowsiness
  • Feeling of numbness, prickling, or heat
  • Flushing
  • Mild headache
  • Tingling sensation
  • Weakness

Serious Side Effects of Imuran (Azathioprine):

  • Bloody diarrhea
  • Bluish fingers or toenails
  • Cold hands and feet
  • Fainting
  • Hearing changes
  • High blood pressure
  • Irregular heartbeat
  • Mental or mood changes
  • Seizure
  • Severe abdominal pain
  • Signs of stroke
  • Weakness on one side of the body
  • Trouble speaking
  • Confusion
  • Sudden vision changes
  • Symptoms of heart attack
    • Chest pain
    • Shortness of breath
    • Unusual sweating
  • Symptoms of serotonin toxicity
    • Agitation
    • Hallucination
    • Loss of coordination
    • Muscle twitching
    • Palpitation
    • Severe vomiting
    • Unexplained fever

Imuran (Azathioprine) is available in the following forms and strengths:

Imuran: Tablet

  • 25 mg
  • 50 mg

Azathioprine: Tablet

  • 50 mg

Before taking Imuran, tell your healthcare provider about your complete medical history, including any allergies, medical conditions, and all medications you are taking. This helps ensure the medication is safe and appropriate for you.

Allergic Reactions

Do not take Imuran if you are allergic to azathioprine, mercaptopurine, or any of the ingredients in the medication.

Some inactive ingredients may also cause allergic reactions in certain people. Tell your healthcare provider if you have had an allergic reaction to azathioprine, mercaptopurine, or any other medication.

Seek emergency medical attention immediately if you develop signs of a serious allergic reaction, including:

  • Rash or hives.
  • Severe itching.
  • Swelling of the face, lips, tongue, or throat.
  • Severe dizziness.
  • Difficulty breathing or swallowing.

Tell Your Healthcare Provider About Your Medical History

Before starting Imuran, tell your healthcare provider if you have or have ever had:

  • Kidney disease.
  • Liver disease.
  • Cancer.
  • A current or recurring infection.
  • A deficiency of the TPMT or NUDT15 enzyme.

People with TPMT or NUDT15 deficiency have a higher risk of serious side effects because their bodies may not break down azathioprine normally. Your healthcare provider may recommend genetic testing or adjust your dose before starting treatment.

Increased Risk of Skin Cancer

Long-term use of Imuran may increase your risk of developing skin cancer.

To help reduce this risk:

  • Limit your time in direct sunlight.
  • Avoid tanning beds and sunlamps.
  • Wear protective clothing, a wide-brimmed hat, and sunglasses when outdoors.
  • Use a broad-spectrum sunscreen with an appropriate SPF.

Tell your healthcare provider if you notice any new or changing moles, sores, or unusual skin changes.

Pregnancy and Breastfeeding

If you are pregnant, planning to become pregnant, or breastfeeding, tell your healthcare provider before taking Imuran.

Azathioprine may harm an unborn baby, so your healthcare provider will carefully weigh the potential benefits and risks before prescribing this medication during pregnancy. If you become pregnant while taking Imuran, contact your healthcare provider promptly to discuss your treatment options.

Increased Risk of Infection

Because Imuran suppresses the immune system, it can increase your risk of developing infections or make existing infections worse.

While taking Imuran:

  • Avoid close contact with people who have contagious illnesses, such as chickenpox, measles, or influenza (flu).
  • Wash your hands frequently and practice good hygiene.
  • Contact your healthcare provider immediately if you develop signs of an infection, including:
    • Fever or chills.
    • Sore throat.
    • Persistent cough.
    • Unusual tiredness.
    • Any other symptoms of illness.

Vaccinations

Tell your healthcare provider that you are taking Imuran before receiving any vaccinations or immunizations.

Avoid receiving live vaccines unless your healthcare provider specifically recommends them. Also, avoid close contact with people who have recently received certain live vaccines, such as the live intranasal flu vaccine, as they may be able to spread the vaccine virus.

Regular Monitoring

Your healthcare provider will schedule regular blood tests while you are taking Imuran to monitor:

  • Blood cell counts.
  • Liver function.
  • Kidney function.

These tests help detect side effects early and ensure your treatment remains safe and effective.

How does Imuran work?

Imuran works by suppressing the immune system. It reduces the activity of certain white blood cells that cause inflammation and immune reactions. This helps decrease inflammation in autoimmune diseases and prevents the immune system from attacking a transplanted organ.

Can Imuran be used to treat ulcerative colitis?

Yes, in some cases. Although Imuran is not approved for all patients with ulcerative colitis, healthcare providers may prescribe it off-label to help maintain remission and reduce flare-ups. It may be used on its own or together with corticosteroids, depending on your treatment plan.

Is Imuran safe to use during pregnancy?

If you are pregnant, planning to become pregnant, or breastfeeding, talk to your healthcare provider before taking Imuran. Azathioprine may not be suitable for everyone during pregnancy, and your healthcare provider will carefully weigh the potential benefits and risks before recommending treatment.

Can Imuran be used to treat myasthenia gravis?

Yes. Imuran is sometimes prescribed off-label to help manage myasthenia gravis, an autoimmune condition that causes muscle weakness. It works by reducing the immune system’s production of antibodies that attack the connection between nerves and muscles, which may help improve muscle strength and reduce symptoms over time.

REVIEWS

Additional Information Book
Generic name:

Azathioprine

Formulation:

Tablet

Strength(s):

25mg, 50mg

Quantities Available:

100

Why customers love Online Pharmacies Canada

Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.

Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.

How to Order

How much Imuran can I order at once from a Canadian pharmacy?

When ordering Imuran (azathioprine) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.

Here’s what you need to know:

Dosage and Quantity: Imuran is commonly prescribed in dosages of 25 mg or 50 mg taken once or multiple times daily depending on the condition being treated. The quantity you would order depends on your prescribed dosage.

For example, if you are prescribed 50 mg twice daily, for a 90-day supply, this means you would order 180 tablets (90 days x 2 tablets per day).

Do you sell azathioprine?

Yes, we sell azathioprine! You can enjoy low prices on your medication by ordering from our website. To place an order, you will need a valid prescription from your healthcare provider, as we require this to dispense the medication safely and accurately. You can conveniently submit your prescription by mail, fax, or by uploading it through your online account during the ordering process.

Do you offer shipping of Imuran (azathioprine) to the United States?

Yes, we ship Imuran (azathioprine) to both the United States and Puerto Rico.

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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Imuran (Azathioprine). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Imuran (Azathioprine).