Cortenema (Hydrocortisone Enema)

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Cortenema Brand

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Hydrocortisone Enema (Generic alternate to Cortenema) Generic

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Table of contents:

Cortenema is a prescribed enema used to treat inflammatory bowel diseases that affect the colon and rectum. This includes ulcerative colitis, ulcerative proctitis, regional enteritis with left side involvement, proctitis, proctocolitis, and proctitis caused by radiation. It contains hydrocortisone enema, a steroid medication that reduces inflammation and swelling in the lower intestines and rectum.

Cortenema is commonly used in combination with other medications. It is administered through the rectum and is typically used once daily for a period of 21 days or until the patient goes into remission both clinically and proctologically.

Uses and Dosage

Cortenema enema should be used in the rectum as directed by your doctor, usually once nightly before bedtime. The dosage and length of treatment will be determined by your medical condition and response to treatment.

To use Cortenema enema, please follow these steps:

  1. Wash your hands thoroughly with soap and water.
  2. Shake the enema well before use.
  3. Lie on your left side with your right knee bent, and gently insert the applicator tip into your rectum.
  4. Slowly squeeze the contents of the enema bottle into your rectum. It is recommended to retain the enema for at least 30 minutes to an hour before having a bowel movement.
  5. After use, dispose of the enema bottle as per the instructions provided on the label.

For optimal results, use Cortenema enema regularly as prescribed, and be patient as it may take 3 to 5 days for improvement to be noticeable.

Do not use more Cortenema enema, use it more often, or use it for longer than prescribed, as this can increase the risk of side effects. If you have been using the enema for a long time (more than 3 weeks), do not stop using it without consulting your doctor, as some conditions may become worse if the treatment is suddenly stopped. Your dose may need to be gradually decreased. Finally, let your doctor know if your condition does not improve after 2 to 3 weeks of treatment or if it worsens.

Side effect

Common Side Effects of Cortenema (Hydrocortisone Enema):

  • Acne
  • Discomfort
  • Dizziness
  • Increased sweating
  • Menstrual changes
  • Mild pain or burning in the rectum
  • Trouble sleeping
  • Unusual hair growth
  • Unusual weight gain

Serious Side Effects of Cortenema (Hydrocortisone Enema):

  • Bone pain
  • Easy bruising
  • Increased thirst
  • Increased urination
  • Irregular heartbeat
  • Muscle weakness
  • Painful urination
  • Persistent headache
  • Persistent rectal bleeding
  • Puffy face
  • Seizures
  • Severe heartburn
  • Skin thinning
  • Slow wound healing
  • Swelling of the lower extremities
  • Unusual bleeding
  • Unusual skin growths
  • Vision problems

Form and Strength

Cortenema (Hydrocortisone Enema) is available in the following forms and strength:

Cortenema: Enema

  • 100 mg


  • Cortenema should be used with caution in patients with heart problems such as chest pain, irregular heartbeats, swelling, and rapid weight gain.
  • Cortenema should also be used with caution in patients with low potassium levels or high blood pressure.
  • Cortenema should not be used in patients with certain medical conditions like fungal or bacterial infections unless it is prescribed by a doctor.
  • The medication may also cause local pain or a burning sensation at the site of administration.
  • Long-term use of Cortenema can lead to complications such as osteoporosis, muscle weakness, and increased risk of infections.
  • Cortenema may increase the risk of infections, so it should be used with caution in patients with a history of infections.
  • Cortenema may mask the symptoms of certain infections, making it difficult to diagnose them.
  • Patients should inform their doctor about any medications they are taking, including over-the-counter drugs and dietary supplements, as they may interact with Cortenema.
  • The use of Cortenema may increase the risk of glaucoma, cataracts, and other eye problems, especially if used for a long time.
  • Patients should avoid stopping Cortenema abruptly as it may lead to withdrawal symptoms, such as fatigue, weakness, joint pain, and muscle aches.

Frequently Asked Questions (FAQ)

How long does Cortenema take to work?

You may notice certain improvements in your symptoms within three to five days of using this enema. It could take a few weeks to a few months before ulcerative colitis could be in remission.

How often should I use Cortenema?

Use Cortenema as directed by your doctor, usually once nightly before bedtime. The duration of treatment is usually 2 to 3 weeks or until symptoms subside.

How long should you leave Cortenema in?

You must leave your retention enema only for as long as you can hold it. If your urge to evacuate is strong, you may expel the enema.

Can Cortenema interact with other medications?

Inform your healthcare provider of all the medications you are taking, including prescription, nonprescription, and herbal products, as they may interact with Cortenema.


It's important to purchase Cortenema from verified Canadian pharmacy.

Additional information

Generic name:

Hydrocortisone Enema





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