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Medrol (Methylprednisolone) is a prescription medication used to treat a variety of conditions, such as allergies, asthma, and skin problems. The active ingredient in Medrol is called Methylprednisolone. Methylprednisolone is a corticosteroid. It works by reducing inflammation and suppressing the body's immune system, allowing it to reduce symptoms associated with certain illnesses.

Methylprednisolone may also be used with other medications for hormone disorders. It is commonly used to treat a variety of inflammatory conditions such as arthritis, lupus, psoriasis, ulcerative colitis, and allergic disorders.

Uses and Dosage

Medrol is a tablet that should be taken orally with food or milk, as directed by your doctor. It is important to carefully follow the prescribed dosage and duration of treatment based on your medical condition and response. Methylprednisolone may have different dosing schedules, so if you are not taking the same dose every day or are taking it every other day, it may be helpful to mark a reminder on your calendar.

Typical dosing for methylprednisolone (Medrol) varies depending on your medical condition and severity, with a dosage ranging from 4 mg to 48 mg per day taken orally. Dosage adjustments may be made by your healthcare provider depending on your response to the medication, as well as any potential side effects that may arise.

Side Effects

Common Side Effects of Medrol (Methylprednisolone):

  • Acne
  • Changes in your mood
  • Headache
  • High blood pressure
  • High blood sugar
  • Insomnia (trouble sleeping)
  • Muscle Weakness
  • Stomach Pain
  • Swelling
  • Weight gain and greater appetite

Serious Side Effects of Medrol (Methylprednisolone):

  • Blurred and tunnel vision
  • Eye pain
  • Seeing halos around lights
  • Severe depression
  • Personality changes
  • Unusual thoughts or behavior
  • Sudden pain in the arm, leg, or back
  • Bloody or tarry stools
  • Coughing up blood or vomit that looks like coffee grounds
  • Seizures
  • Leg cramps
  • Constipation
  • Irregular heartbeats
  • Fluttering in your chest
  • Increased thirst or urination

Form and Strength

Medrol (Methylprednisolone)) is available in the following forms and strengths:

Medrol: Tablet

  • 2 mg
  • 4 mg
  • 8 mg
  • 16 mg


  • Before using methylprednisolone, inform your healthcare provider about any allergies you have to it or to prednisone, as well as any other allergies. Some inactive ingredients in the product may also cause allergic reactions or other problems, so speak with your pharmacist for more information.
  • Do not increase your dose or use methylprednisolone more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase.
  • Do not stop taking Medrol without consulting your doctor. If you suddenly stop using it, you may have withdrawal symptoms (such as weakness, weight loss, nausea, muscle pain, headache, tiredness, and dizziness). Your dose may need to be gradually decreased.
  • Long-term use of Medrol can weaken bones and increase the risk of fractures in adults and elderly individuals. Additionally, its use may slow the growth of children and infants, particularly when used for an extended period. It is advisable to discuss any concerns with a healthcare provider.
  • Using Medrol may increase the risk of stomach bleeding. Limit alcoholic beverages while taking this medication, as daily alcohol consumption can further increase the risk.

Frequently Asked Questions (FAQ)

How is methylprednisolone taken?

Methylprednisolone is typically taken orally in the form of a tablet, with or without food. The dosage and length of treatment are based on your medical condition and response to treatment.

What is the typical dosage of methylprednisolone?

The typical dosage of methylprednisolone can range from 4 mg to 48 mg by mouth per day, depending on your condition and how severe it is. Your healthcare provider may adjust your dosage based on your response to the medication and any side effects that may occur.

How long does it take for methylprednisolone to start working?

The time it takes for methylprednisolone to start working may vary depending on the condition being treated. In some cases, you may feel the effects within a few hours or days, while in others it may take longer.

Can methylprednisolone be stopped abruptly?

No, methylprednisolone should not be stopped abruptly as it may lead to withdrawal symptoms such as fatigue, weakness, nausea, and joint pain.


Additional information

Generic name:



Blister Tablet, Tablet


2mg, 4mg, 8mg, 16mg

Quantities Available:

28, 40, 60, 84, 100


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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Medrol (Methylprednisolone). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Medrol (Methylprednisolone).