Colcrys (Colchicine)

Indications

Colcrys scientifically known as colchicine is a prescription medication used to treat gout flares and familial Mediterranean fever (FMF). Colchicine belongs to a class of drugs called anti-gout agents. It works by decreasing swelling and lessening the buildup of uric acid crystals that cause pain in the affected joints.

Colchicine is not a pain medication and should not be used to relieve other causes of pain. It can be used to prevent attacks of pain in the abdomen, chest, or joints caused by a certain inherited disease FMF.

Uses and Dosage

Colchicine is available in tablet form and should be taken orally, with or without food, once or twice a day as prescribed by your healthcare provider. Do not take more than this recommended dose or take it more frequently, without consulting your healthcare provider. If you do not experience relief or have another attack within several days after treatment, talk to your doctor before taking additional doses of medication.

The dosage and duration of treatment varies depending on the medical condition being treated and the individual's response to the medication. For acute gout flares in adults, the recommended dose is 1.2 mg followed by 0.6 mg one hour later, given orally. For prophylaxis of gout flares, the recommended dose is 0.6 mg orally once or twice daily. The dosage may be adjusted based on the patient's response to treatment and underlying medical conditions.

Side effect

Common Side Effects of Colcrys (Colchicine):

• Nausea
• Cramps
• Abdominal discomfort
• Diarrhea
• Vomiting

Serious Side Effects of Colcrys (Colchicine):

• Unusual bleeding
• Easy bruising
• Severe diarrhea and vomiting
• Tingling sensation on the toes and fingers
• Unusual fatigue
• Palpitations
• Changes in urine output
• Shortness of breath
• Signs of infection (fever, chills, persistent sore throat)

Form and Strength

Colcrys (Colchicine) is available in the following forms and strength:

Colchicine: Tablet

• 0.5 mg
• 0.6 mg

Caution

• Colcrys (Colchicine Tablets) can cause various side effects. The possible side effects are not listed, but you can check with your doctor to know more about them.
• Colcrys can interact with other drugs, including prescription/nonprescription drugs and herbal products. Keep a list of all the products you use to let your doctor know
• Colcrys should be used with caution in patients with kidney, liver, or heart problems, and those who consume grapefruit or grapefruit juice.
• Colchicine can cause serious health complications in some people. Talk to your healthcare provider about the risks before using this drug.
• The dosage of Colcrys should be carefully determined by a healthcare provider as the recommended doses can differ depending on the use of the medication. Using too much can cause serious side effects or death.
• The effects of Colcrys on pregnancy and breastfeeding are unclear. Women who are pregnant or breastfeeding should consult with their healthcare provider before using this medication.
• Some people may have allergic reactions to Colcrys. Signs of an allergic reaction include rash, itching, swelling, dizziness, or trouble breathing. Seek medical attention immediately if any of these symptoms occur.
• The safety and efficacy of Colcrys in children have not been established, and it is not recommended for use in children under 4 years of age.

Frequently Asked Questions (FAQ)

Is Colcrys safe to take during pregnancy?

The safety of Colcrys during pregnancy is not well established. You should talk to your doctor if you are pregnant or planning to become pregnant.

Can I drink alcohol while taking Colcrys?

You should avoid drinking alcohol while taking Colcrys, as it may increase your risk of developing certain side effects, such as dizziness or drowsiness.

Can I take Colcrys if I'm allergic to it?

No, you should not take Colcrys if you are allergic to it. You should talk to your doctor if you are unsure about your allergies or if you have had an allergic reaction to any medication in the past.

How quickly does Colcrys work?

Colcrys can start working within a few hours of taking it for a gout attack. However, it may take several days of regular use to prevent future gout flares.

Does Colcrys interact with other medications?

Colcrys can interact with certain medications, including statins, anti-fungal medications, and antibiotics. You should talk to your doctor or a healthcare professional about any medications you are taking and their potential interactions with Colcrys.

Resources

• https://www.drugs.com/colcrys.html
• https://www.rxlist.com/colcrys-drug.htm
• https://www.webmd.com/drugs/2/drug-152819/colcrys-oral/details
• https://medlineplus.gov/druginfo/meds/a682711.html
• https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=5ecaa34e-1bed-49a5-b97c-a8f8c0d885a7
• https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/022351lbl.pdf