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Synvisc-One is a type of viscosupplement injection used for the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative non-pharmacologic therapy and simple analgesics, such as acetaminophen. Synvisc-One is derived from a natural substance called hylan G-F 20, which is similar to the fluid that surrounds the joints in your body.
Synvisc-One is administered as a single intra-articular injection and supplements the fluid in your knee to help lubricate and cushion the joint, providing pain relief for up to six months. Synvisc-One should not be injected into the knees of patients having knee joint infections or skin diseases or infections around the injection site.
Synvisc-One is supplied in a pre-filled glass syringe with a total volume of 10 mL. The syringe contains three doses (48 mg) of hylan G-F 20 to take together as single dosages, a type of sodium hyaluronate. Hylan G-F 20 is administered by a licensed healthcare provider and is intended to be given in a single dose. The contents of the syringe are sterile and nonpyrogenic, meaning that they are free from bacteria and other harmful substances that could cause an infection or a fever.
To avoid increased side effects, the injection should not be given into a vein or artery. Patients should also avoid any strenuous activities that put pressure on the knee joint for at least 48 hours after receiving the injection, such as jogging, tennis, heavy lifting, or standing for more than an hour.
After the injection, initial pain and swelling in the knee joint are normal, and if it continues or worsens, patients should consult their doctor immediately.
Synvisc-One (Hylan GF 20) is available in the following forms and strengths:
Synvisc is injected directly into your knee joint. The Synvisc brand of hylan G-F 20 is usually given once every week until you have received 3 injections.
Tell your doctor for instructions if you miss an appointment for your hylan G-F 20 injection.
Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.
For at least 48 hours after your injection, avoid jogging, strenuous activity, or high-impact sports such as soccer or tennis. Also avoid weight-bearing activity or standing for longer than 1 hour at a time. Ask your doctor how long to wait before you resume these activities.
| Generic name: | Hylan GF 20 |
|---|---|
| Formulation: | Injection Kit |
| Strength(s): | 48mg/syr |
| Quantities Available: | 1syr |
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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Synvisc-One (Hylan GF 20). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Synvisc-One (Hylan GF 20).
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