Indications
Clinoril scientifically known as Sulindac is a prescription medicine used to treat the symptoms of Ankylosing Spondylitis, Osteoarthritis, Rheumatoid Arthritis, Shoulder Pain, and Gout. It is a nonsteroidal anti-inflammatory drug (NSAID). It works by blocking the production of prostaglandins, which are substances in the body that cause pain, swelling and inflammation.
Clinoril is used to treat pain, inflammation, and stiffness caused by conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It is available in tablet form and is usually taken once or twice daily with food to minimize stomach upset.
Uses and Dosage
Sulindac is taken orally in tablet form, as directed by your doctor, usually twice daily. You take this medication with a full glass of water (8 ounces/240 milliliters) unless your doctor provides different instructions. To avoid stomach upset, take tablet with food, milk, or an antacid. Additionally, avoid lying down for at least 10 minutes after taking this medication.
The dosage of Sulindac varies depending on your individual treatment needs.
- For osteoarthritis, rheumatoid arthritis, and arthritis of the spine (ankylosing spondylitis), the typical starting dose is 150 mg taken by mouth twice daily with food, and the maximum daily dose is 400 mg.
- For gout (gouty arthritis), the typical dose is 200 mg taken by mouth twice daily with food, and the maximum daily dose is 400 mg. Treatment usually lasts 7 days.
- For sharp shoulder pain (acute subacromial bursitis/supraspinatus tendinitis), the typical dose is 200 mg taken by mouth twice daily with food, and the maximum daily dose is 400 mg. Treatment usually lasts 7-14 days.
Side Effect
Common Side Effects of Clinoril (Sulindac):
- Constipation
- Diarrhea
- Dizziness
- Gas
- Headache
- Indigestion
- Itching
- Loss of appetite
- Nausea
- Nervousness
- Rash
- Ringing in your ears
- Stomach pain
- Vomiting
Serious Side Effects of Clinoril (Sulindac):
- Bloody or tarry stools
- Burning eyes
- Changes in your vision
- Chest pain spreading to your jaw or shoulder
- Clay-colored stools
- Cold hands and feet
- Coughing up blood
- Dark urine
- Difficulty breathing
- Fever
- Lightheadedness
- Little or no urinating
- Loss of appetite
- Painful or difficult urination
- Pale skin
- Rapid weight gain
- Red or purple skin rash with blistering and peeling,
- Runny nose
- Shortness of breath
- Skin pain
- Slurred speech
- Sneezing
- Sore throat
- Swelling
- Unusual tiredness
- Upper stomach pain
- Wheezing
- Yellowing of the skin or eyes (jaundice)
Form and Strength
Clinoril (Sulindac) is available in the following forms and strength:
Sulindac: Tablet
- 150 mg
Caution
- Sulindac belongs to a class of drugs called NSAIDs (Nonsteroidal anti-inflammatory drugs) and may increase the risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke.
- Clinoril may cause serious gastrointestinal (GI) adverse events, including bleeding, ulceration, and perforation of the stomach or intestines.
- Sulindac may cause an increased risk of serious skin reactions, including Stevens-Johnson syndrome and toxic epidermal necrolysis.
- Clinoril may cause an increased risk of liver injury, especially in patients with pre-existing liver disease.
- Sulindac tablets should be used with caution in patients with a history of heart failure or hypertension.
- It may cause dizziness or drowsiness in some people. If you experience these side effects, avoid driving or operating heavy machinery until you know how the medication affects you.
- Avoid alcohol while taking Clinoril (Sulindac) since alcohol may increase the risk of gastrointestinal side effects.
- Sulindac should be used with caution in patients with a history of asthma.
- Clinoril may cause an increased risk of bleeding, especially in patients taking anticoagulants or those with a history of bleeding disorders.
- Sulindac tablet may cause an increased risk of renal toxicity, especially in patients with pre-existing renal impairment.
Frequently Asked Questions (FAQ)
Is Clinoril (Sulindac) a member of the NSAID class of drugs?
Yes, Clinoril (Sulindac) belongs to the class of drugs called NSAIDs, which includes ibuprofen, naproxen, diclofenac, and others.
What should I tell my healthcare provider before taking Clinoril (Sulindac)?
You should tell your healthcare provider about all your medical conditions, including any history of heart failure, hypertension, asthma, bleeding disorders, or liver or kidney disease. You should also tell your healthcare provider about all the medications you are taking, including prescription and over-the-counter drugs, vitamins, and herbal supplements.
Can Clinoril (Sulindac) interact with other medications?
Yes, there are many drugs that can interact with Clinoril (Sulindac), including some antidepressants, blood pressure medications, blood thinners, and others. You should always tell your healthcare provider about all the medications you are taking to avoid drug interactions.
What should I do if I miss a dose of Clinoril (Sulindac)?
If you miss a dose of Clinoril (Sulindac), take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
REVIEWS