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Clinoril (active ingredient: sulindac) is a prescription nonsteroidal anti-inflammatory drug (NSAID). It is used to reduce pain, swelling, stiffness, and inflammation caused by several joint and musculoskeletal conditions.
Clinoril does not cure these conditions. Instead, it helps control symptoms so movement and daily activities may become more comfortable.
Indications
Clinoril is used to relieve the signs and symptoms of osteoarthritis.
Osteoarthritis develops when the protective cartilage that cushions the ends of bones gradually wears down. As the condition progresses, joints may become painful, stiff, or swollen.
Common symptoms may include:
Osteoarthritis frequently affects joints such as the knees, hips, hands, and spine.
Clinoril helps reduce inflammation and pain around the affected joints. This may make walking, bending, exercising, or performing other daily activities easier.
However, Clinoril does not rebuild damaged cartilage or cure osteoarthritis.
Clinoril may also be used to relieve symptoms of rheumatoid arthritis.
Rheumatoid arthritis is a long-term autoimmune condition. It occurs when the immune system mistakenly attacks the tissues that line the joints.
This immune reaction can cause inflammation that leads to:
Clinoril can help reduce pain, swelling, and stiffness associated with rheumatoid arthritis.
However, it does not treat the underlying autoimmune cause of the condition or prevent disease progression in the same way as disease-modifying antirheumatic drugs.
Your healthcare provider may prescribe Clinoril together with other treatments as part of a broader rheumatoid arthritis treatment plan.
Clinoril may be used to relieve pain and inflammation during an acute gout attack.
Gout develops when uric acid crystals collect inside or around a joint. These crystals can trigger sudden and intense inflammation.
A gout flare may cause:
The big toe is commonly affected, but gout can also occur in the ankles, knees, wrists, fingers, and other joints.
Clinoril helps reduce the inflammatory response during a gout attack, which may lessen pain and swelling.
It does not lower uric acid levels or prevent future attacks by itself. Other medications may be needed for long-term uric acid control.
Clinoril belongs to a group of medications called nonsteroidal anti-inflammatory drugs, or NSAIDs.
Reduces Prostaglandin Production
When tissues are injured or inflamed, the body produces substances called prostaglandins.
Prostaglandins contribute to:
Sulindac reduces the production of prostaglandins by blocking cyclooxygenase enzymes involved in their formation.
Reduces Joint Inflammation
Lower prostaglandin levels can decrease inflammation in and around affected joints.
As inflammation improves, swelling and tenderness may also decrease.
Helps Relieve Pain
Prostaglandins make pain-sensing nerves more sensitive.
By decreasing prostaglandin production, Clinoril can help reduce the intensity of pain caused by arthritis or an acute inflammatory condition.
Helps Improve Joint Movement
Pain, swelling, and stiffness can make it difficult to move an affected joint.
By reducing these symptoms, Clinoril may make movement easier and help improve comfort during everyday activities.
Clinoril Controls Symptoms
Clinoril mainly provides symptomatic relief.
For osteoarthritis, it can help manage pain and stiffness but does not reverse cartilage damage.
For rheumatoid arthritis, it reduces inflammation and discomfort but does not correct the underlying autoimmune disorder.
For acute gout, it can help control inflammation during a flare but does not remove excess uric acid from the body.
The amount of relief you experience can depend on the condition being treated, the severity of your symptoms, and your individual response to sulindac.
Some people may notice pain relief relatively soon after starting treatment, while the full anti-inflammatory benefit may take longer with ongoing use.
Take Clinoril exactly as prescribed by your healthcare provider.
Like other NSAIDs, Clinoril can cause serious side effects, particularly when taken at higher doses or for long periods.
Your healthcare provider will generally aim to use the lowest dose that effectively controls your symptoms for the shortest appropriate treatment period.
Do not increase your dose or take Clinoril more frequently without speaking with your healthcare provider.
Tell your healthcare provider about your complete medical history and all medications you take before starting Clinoril.
This is especially important if you have a history of stomach ulcers, gastrointestinal bleeding, kidney disease, heart disease, high blood pressure, or other conditions that may affect the safety of NSAID treatment.
Contact your healthcare provider if your symptoms do not improve, become worse, or you develop new or concerning symptoms during treatment.
Clinoril is taken by mouth as a tablet. It is commonly taken twice daily, although the exact dose and length of treatment depend on the condition being treated.
Take Clinoril exactly as prescribed by your healthcare provider. Do not take a larger dose or use it more often than recommended.
Take Clinoril with food to help reduce stomach irritation.
You may also take it with milk or an antacid if your healthcare provider recommends it.
Taking Clinoril with food does not completely prevent stomach problems, so tell your healthcare provider if you develop ongoing stomach pain, indigestion, or other digestive symptoms.
Swallow Clinoril with a full glass of water, about 8 ounces or 240 mL, unless your healthcare provider gives you different instructions.
Avoid lying down for at least 10 minutes after taking a dose.
For osteoarthritis, a common dose is 150 mg taken twice daily with food.
Osteoarthritis can cause joint pain, stiffness, swelling, and reduced movement. Clinoril helps reduce pain and inflammation, which may make movement and daily activities easier.
Your healthcare provider may adjust your dose based on your symptoms and how well you tolerate the medication.
The total daily dose should generally not exceed 400 mg.
For rheumatoid arthritis, a common dose is 150 mg taken twice daily with food.
Clinoril may help reduce joint pain, swelling, stiffness, and inflammation.
Because rheumatoid arthritis is a long-term autoimmune condition, Clinoril may be used along with other medications that treat the underlying disease.
The maximum recommended total daily dose is generally 400 mg.
For ankylosing spondylitis, a common dose is 150 mg taken twice daily with food.
Ankylosing spondylitis causes inflammation that mainly affects the spine and nearby joints. Clinoril can help reduce pain and stiffness associated with this inflammation.
Your healthcare provider may adjust the dose depending on your response.
The total daily dose should generally not exceed 400 mg.
For an acute gout attack, a common dose is 200 mg taken twice daily with food.
Treatment is usually short term and may last about 7 days.
Clinoril helps reduce pain, redness, swelling, and inflammation during a gout flare.
It does not lower uric acid levels or prevent future gout attacks by itself.
Clinoril may also be prescribed for acute subacromial bursitis or supraspinatus tendinitis.
These conditions can cause sudden shoulder pain, inflammation, tenderness, and difficulty moving the arm.
A common dose is 200 mg taken twice daily with food.
Treatment may last about 7 to 14 days, depending on your symptoms and your healthcare provider’s instructions.
The maximum recommended dose of Clinoril is generally 400 mg per day.
Do not take more than the prescribed amount.
Taking higher doses can increase the risk of serious side effects, including stomach ulcers or bleeding, kidney problems, high blood pressure, heart attack, and stroke.
If your healthcare provider tells you to take Clinoril twice daily, try to take each dose at about the same times every day.
For example, you may be instructed to take one dose in the morning and another in the evening.
A regular schedule can help you remember your medication and maintain more consistent symptom relief.
Clinoril may begin reducing pain within several hours after a dose.
However, when it is used for an ongoing inflammatory condition such as arthritis, it may take longer to notice the full anti-inflammatory benefit.
Continue taking it as directed rather than increasing the dose if your symptoms do not improve immediately.
If you miss a dose of Clinoril, take it when you remember unless it is almost time for your next scheduled dose.
If your next dose is close, skip the missed dose and continue with your normal schedule.
Do not take two doses at the same time to make up for a missed dose.
Clinoril belongs to the NSAID family.
Do not routinely combine it with other NSAIDs such as ibuprofen, naproxen, or similar pain relievers unless your healthcare provider tells you to do so.
Combining NSAIDs can increase the risk of stomach bleeding, kidney problems, and other side effects.
Alcohol can increase the risk of stomach irritation and gastrointestinal bleeding associated with NSAIDs.
Ask your healthcare provider whether alcohol is safe for you while taking Clinoril.
Older adults may be more sensitive to some NSAID side effects, particularly stomach bleeding, kidney problems, and cardiovascular complications.
A healthcare provider may recommend closer monitoring or the lowest effective dose.
Tell your healthcare provider if you have kidney or liver disease before taking Clinoril.
These conditions may affect how safely the medication can be used and may require closer monitoring.
NSAIDs such as Clinoril are generally used at the lowest dose that effectively controls symptoms for the shortest appropriate treatment period.
This approach helps reduce the risk of serious side effects.
Take Clinoril exactly as prescribed by your healthcare provider.
Do not change the dose, increase how often you take it, or continue treatment longer than recommended without medical advice.
Contact your healthcare provider if your pain or inflammation does not improve, becomes worse, or if you develop new or concerning symptoms during treatment.
Clinoril (Sulindac) is available in the following forms and strength:
Clinoril belongs to a group of medicines called nonsteroidal anti-inflammatory drugs (NSAIDs).
NSAIDs may increase the risk of serious cardiovascular problems, including heart attack and stroke. The risk may be higher with longer use, higher doses, or in people who already have heart disease or cardiovascular risk factors.
Seek immediate medical attention if you develop chest pain, sudden shortness of breath, weakness on one side of the body, or difficulty speaking.
Clinoril may cause serious gastrointestinal problems, including stomach ulcers, bleeding, or perforation of the stomach or intestines.
These problems can sometimes occur without warning.
Contact your healthcare provider right away if you develop severe stomach pain, vomit that looks like coffee grounds, bloody vomit, black stools, or bloody stools.
Sulindac may rarely cause serious skin reactions, including Stevens-Johnson syndrome and toxic epidermal necrolysis.
Stop taking Clinoril and seek medical attention if you develop a severe rash, blistering, peeling skin, sores in the mouth, or swelling of the face.
Clinoril may cause liver injury in some people.
Tell your healthcare provider if you have liver disease or a history of liver problems. Your healthcare provider may recommend blood tests to monitor liver function during treatment.
Contact your healthcare provider if you develop yellowing of the skin or eyes, dark urine, unusual tiredness, nausea, or pain in the upper right side of the abdomen.
Clinoril should be used carefully in people with high blood pressure or heart failure.
NSAIDs may cause fluid retention, swelling, or increases in blood pressure.
Your healthcare provider may check your blood pressure and monitor for swelling, sudden weight gain, or worsening shortness of breath.
Clinoril may cause dizziness or drowsiness in some people.
Avoid driving, operating machinery, or doing activities that require full alertness until you know how the medication affects you.
Alcohol may increase the risk of stomach irritation, ulcers, and gastrointestinal bleeding while taking Clinoril.
Ask your healthcare provider whether alcohol is safe for you during treatment.
Tell your healthcare provider if you have asthma, especially if aspirin or another NSAID has caused wheezing, breathing problems, or an allergic reaction in the past.
Some people with aspirin-sensitive asthma can have a serious reaction to NSAIDs such as Clinoril.
Clinoril may increase the risk of bleeding.
This risk may be higher if you take anticoagulants, antiplatelet medicines, corticosteroids, or certain antidepressants, or if you have a bleeding disorder.
Tell your healthcare provider about all medicines and supplements you take before starting Clinoril.
Clinoril may reduce kidney function and can cause kidney injury, especially in people who already have kidney disease.
The risk may also be higher in older adults or people who are dehydrated, have heart failure, or take certain blood pressure medicines or diuretics.
Your healthcare provider may monitor your kidney function during treatment. Contact your healthcare provider if you notice decreased urination, swelling in your legs or feet, unusual tiredness, or sudden weight gain.
Yes. Clinoril belongs to a group of medicines called nonsteroidal anti-inflammatory drugs, or NSAIDs. Other NSAIDs include ibuprofen, naproxen, and diclofenac. These medicines help reduce pain, swelling, and inflammation.
Before taking Clinoril, tell your healthcare provider about all of your medical conditions. This is especially important if you have or have had heart failure, high blood pressure, asthma, bleeding problems, stomach ulcers, liver disease, or kidney disease. You should also tell your healthcare provider about all prescription medicines, over-the-counter drugs, vitamins, and herbal supplements you take.
Yes. Clinoril can interact with several types of medications, including blood thinners, blood pressure medicines, diuretics, antidepressants, corticosteroids, and other NSAIDs. Some of these interactions may increase the risk of bleeding, kidney problems, or other side effects. Always give your healthcare provider a complete list of all prescription medicines, over-the-counter drugs, vitamins, and supplements you take before starting Clinoril.
If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time or take extra Clinoril to make up for a missed dose.
| Generic name: | Sulindac |
|---|---|
| Formulation: | Tablet |
| Strength(s): | 150mg |
| Quantities Available: | 100 |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Clinoril (sulindac) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.
Here’s what you need to know:
Dosage and Quantity: Clinoril is commonly prescribed in dosage of 150 mg, taken once or twice daily depending on your healthcare provider’s recommendation. For a 90-day supply, this means you would order 90 tablets if taking once daily (90 days x 1 tablet per day), or 180 tablets if taking twice daily (90 days x 2 tablets per day).
Yes, we sell sulindac at our pharmacy, and you can enjoy low prices. However, to purchase sulindac, you will need a valid prescription from your healthcare provider. We require this to dispense the medication safely and appropriately. You can provide your prescription by mailing, faxing, or uploading it through your online account.
Yes, we ship Clinoril (sulindac) to both the United States and Puerto Rico.
Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Clinoril (Sulindac). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Clinoril (Sulindac).
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