Table of contents:

---

Drug Description

Indications

Durolane is indicated for the treatment of pain in osteoarthritis of the knee in patients who have failed to respond adequately to other treatments. It is a single-injection treatment that is used to relieve knee pain when other arthritis medications have not been effective. It works by supplementing the natural hyaluronic acid in the joint fluid to improve lubrication and allow for smooth joint movement.

Durolane is a non-animal, biofermentation-derived product that is generally considered safe and effective for use in treating knee osteoarthritis. However, as with any medical treatment, it may not be suitable for everyone and should only be used as directed by a healthcare provider.

Uses and Dosage

The use of Durolane should be directed by a healthcare provider who is experienced with the injection technique required for the product. Typically, Durolane is given as a single injection to the affected knee joint. Before the injection, the healthcare provider may remove any joint effusion or swelling. Local anesthesia via a subcutaneous injection or a topical freezing agent may be used prior to the Durolane injection.

The recommended dosage for Durolane is 3 ml per knee or hip joint. Use separate syringes for each joint. Following the injection, some patients may experience transient pain or swelling at the injection site. As with any medical treatment, follow the healthcare provider’s instructions for the use of Durolane. If you have any questions or concerns about the use of Durolane, talk to your healthcare provider.

Side Effect

Common Side Effects of Durolane (Hyaluronic acid, stabilized):

• Joint pain
• Mild pain
• Muscle discomfort
• Muscle stiffness headache
• Swelling
• Warmth on the injection site

Serious Side Effects of Durolane (Hyaluronic acid, stabilized):

• Bleeding
• Blisters or discoloration around the area
• Severe itching
• Signs of infection (fever, chills, inflammation on the site)

Form and Strength

Durolane (Hyaluronic acid, stabilized) is available in the following forms and strength:

·        Durolane: Injection

• 60mg/3mL

Cautions

• Allergic reaction: Patients who are allergic to hyaluronic acid should not receive Durolane injections.
• Infection: Durolane injections should not be given to patients with active infections or skin diseases.
• Bleeding: The injection may cause bleeding in patients who have bleeding disorders or are taking blood thinners.
• Joint effusion: The healthcare provider may need to remove any joint effusion or swelling before the injection.
• Temporary pain or swelling: Some patients may experience transient pain or swelling at the injection site.
• Limited effectiveness: Durolane may not be effective in all patients and may not provide long-lasting pain relief.

Frequently Asked Questions (FAQ)

Is Durolane safe?

Durolane is generally considered safe for use in treating knee osteoarthritis. However, as with any medical treatment, it may not be suitable for everyone and should only be used as directed by a healthcare provider.

How long does the effect of Durolane last?

The effect of Durolane can last for up to six months.

How long does the Durolane injection take?

The Durolane injection usually takes only a few minutes to administer.

How soon can I expect to feel pain relief after a Durolane injection?

Pain relief may vary from patient to patient, but some patients may start to experience relief within a few days of the injection.

Resources

• https://www.drugs.com/mtm/durolane-injection.html
• https://www.accessdata.fda.gov/cdrh_docs/pdf17/P170007C.pdf
• https://sportdoctorlondon.com/durolane-injection/