Indications
Orudis SR (active ingredient: ketoprofen) is a prescription medication indicated for the following:
- Rheumatoid Arthritis: Orudis SR is used for the treatment of signs and symptoms of rheumatoid arthritis, helping to reduce inflammation, pain, and stiffness.
- Osteoarthritis: It is also indicated for the treatment of signs and symptoms of osteoarthritis, providing relief from joint pain and swelling.
Orudis SR belongs to a class of drugs known as nonsteroidal anti-inflammatory drugs (NSAIDs), which work by inhibiting the cyclooxygenase (COX) enzymes, thereby reducing the production of prostaglandins that cause inflammation, pain, and fever.
Use and Dosage
Ketoprofen SR Tablets should be swallowed whole with a full glass of water. Do not chew, crush, or break the tablets. You should take the tablet at the same time every day, preferably in the morning or evening with or without food.
The recommended dosage of Ketoprofen SR Tablets depends on the condition being treated, age, medical history, and other factors. Elderly patients may require lower doses. Generally, for adults, the recommended starting dosage for pain and inflammation is 200 mg once daily. The dosage can be increased up to a maximum of 400 mg once daily, taken as a single dose in the morning or evening.
The tablet should be stored in its original package in a dry place away from moisture and heat. Avoid exposing the tablets to excess sunlight. The SR form provides sustained pain relief for up to 24 hours with once-daily dosing.
Side Effects
Common Side Effects of Orudis SR (Ketoprofen SR):
- Dizziness
- Drowsiness
- Headache
- Disorientation
- Buzzing or ringing in the ears
Serious Side Effects of Orudis SR (Ketoprofen SR):
- Constipation
- Cramps
- Diarrhea
- Heartburn
- Indigestion
- Loss of appetite
- Pain in the stomach
- Stomach upset including nausea (feeling sick)
- Ulcers
- Vomiting
Forms and Strength
Orudis SR (Ketoprofen SR) is available in the following forms and strength:
Ketoprofen SR: Extended-Release Tablet
- 200mg
Cautions
- Peptic ulcer: Ketoprofen can worsen peptic ulcers, so it should be used with caution in patients with a history of ulcers.
- Kidney and liver disease: Patients with severe kidney or liver problems should use ketoprofen with caution due to increased risk of side effects.
- Elderly: Elderly patients are at higher risk of side effects and complications, so lower doses may be needed.
- Heart conditions: Ketoprofen should be used with caution in patients with heart problems.
- Fluid retention: Ketoprofen can cause swelling of the ankles and feet, so patients with cardiovascular conditions should be monitored.
- Use caution in patients with kidney disease since they may have higher systemic exposure to ketoprofen. Lower dose may be needed in these patients.
- Elderly patients are at higher risk of side effects like gastrointestinal bleeding and kidney toxicity, so a lower dose is recommended.
- Ketoprofen can cause reduced efficacy of medications used to manage high blood pressure, diabetes, or heart disease. Close monitoring is required.
- Ketoprofen may increase the risk of heart attack and stroke in patients with risk factors like high blood pressure, high cholesterol, or smoking.
Frequently Asked Questions (FAQ)
How does Orudis SR work?
Orudis SR works by blocking the enzyme cyclooxygenase (COX) which reduces prostaglandin production and subsequently reduces inflammation and pain.
When should I take Orudis SR?
You should take Orudis SR once daily in the evening with or after food. Taking it at the same time each day will provide a more consistent effect.
How long does Orudis SR take to work?
Orudis SR is an extended-release formulation, so it may take up to a few hours to start relieving pain. The effects typically last around 12 hours.
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