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Depakote Sprinkles (Divalproex) Shopper Approved

Prescription Prescription Required FormationFormulation: Delayed Release Capsule

Depakote Sprinkles

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Prescription Prescription Required FormationFormulation: Delayed Release Capsule

Divalproex

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Depakote Sprinkle Capsules contain divalproex sodium, a prescription medicine that is converted to valproate in the body. It belongs to a group of medicines called anticonvulsants, also known as antiepileptic drugs.

The Depakote Sprinkle Capsule formulation is specifically approved to treat certain types of seizures, either by itself or together with other seizure medicines.

Epilepsy and Seizure Disorders

Depakote Sprinkles may be prescribed for complex partial seizures in adults and children 10 years of age and older. Complex partial seizures, also called focal impaired-awareness seizures, begin in one area of the brain and can affect awareness or behavior.

During a seizure, a person may experience symptoms such as:

  • Staring or appearing confused
  • Repetitive movements
  • Changes in awareness
  • Unusual sensations
  • Temporary difficulty responding to others

Depakote Sprinkles help stabilize abnormal electrical activity in the brain. This can help reduce how often seizures occur and improve seizure control.

Absence Seizures

Depakote Sprinkles may also be used to treat simple and complex absence seizures, with or without other types of seizures.

Absence seizures often cause a brief loss of awareness. A person may suddenly stop what they are doing, stare for a few seconds, and then return to normal activity without remembering what happened.

Depakote Sprinkles help control the abnormal brain activity that causes these episodes.

Can Depakote Sprinkles Be Used With Other Seizure Medicines?

Yes. Depakote Sprinkles may be used alone or together with other seizure medications, depending on the type and severity of the seizure disorder.

Your healthcare provider will decide whether divalproex should be used alone or as part of a combination treatment.

What About Bipolar Disorder?

Divalproex sodium is also used in some formulations to treat manic episodes associated with bipolar disorder. However, it is important to distinguish the medication itself from the specific Depakote Sprinkle Capsule formulation.

The current prescribing information for Depakote Sprinkle Capsules specifically lists seizure disorders as its approved uses. Other Depakote formulations have approved indications for mania.

Your healthcare provider may determine whether a particular divalproex formulation is appropriate based on your condition.

What About Migraine Prevention?

Divalproex is also used in certain formulations to help prevent migraine headaches. However, migraine prevention is an approved indication for Depakote delayed-release tablets and Depakote ER, rather than specifically for Depakote Sprinkle Capsules.

These medicines are taken regularly to help reduce migraine attacks. They are not intended to provide immediate relief from a migraine that has already started.

How Do Depakote Sprinkles Work?

Depakote Sprinkles affect chemical messengers and electrical signals in the brain. Valproate helps calm excessive nerve activity, which can make the brain’s electrical activity more stable.

This effect helps prevent the sudden bursts of abnormal electrical activity that can cause seizures.

Why Are They Called “Sprinkles”?

Depakote Sprinkle Capsules contain specially coated delayed-release particles of divalproex sodium. Each capsule contains the equivalent of 125 mg of valproic acid.

The capsule may be swallowed whole. For people who have difficulty swallowing capsules, it may also be opened and the contents sprinkled onto a small amount of soft food, such as applesauce or pudding. The particles should be swallowed without chewing.

How Long Does Depakote Sprinkles Take to Work?

How quickly the medicine works can vary from person to person. For seizure treatment, the goal is to maintain enough medicine in the body to help prevent future seizures.

Your healthcare provider may gradually adjust your dose until your seizures are well controlled. Blood tests may sometimes be used to measure valproate levels and make sure your dose is appropriate.

Why Is Regular Dosing Important?

Depakote Sprinkles work best when taken regularly as prescribed. Missing doses can lower the amount of medicine in your body and may increase your risk of having a seizure.

Do not change your dose or suddenly stop taking Depakote Sprinkles without speaking with your healthcare provider. Suddenly stopping an antiepileptic medicine can cause seizures to become worse or occur more often.

Important Safety Information

Valproate medicines such as Depakote can cause serious side effects, including liver problems, pancreatitis, and problems during pregnancy. They also require special caution in people with certain liver, metabolic, or mitochondrial disorders.

Tell your healthcare provider about your complete medical history and all medicines or supplements you take before starting treatment.

Your healthcare provider may order blood tests during treatment to check your liver function, blood cell counts, and sometimes the amount of valproate in your blood.

Important Pregnancy Warning

Valproate can cause major birth defects and developmental problems in an unborn baby. Its use during pregnancy requires careful consideration, especially when other effective treatments are available.

If you are pregnant, planning to become pregnant, or could become pregnant, discuss the risks and treatment options with your healthcare provider.

Do not suddenly stop Depakote Sprinkles if you become pregnant, particularly if you take it for seizures. Contact your healthcare provider promptly so your treatment can be reviewed safely.

Depakote Sprinkle Capsules are taken by mouth and may be taken with food if they cause stomach upset. Follow the exact schedule given by your healthcare provider.

You may swallow the capsule whole with water. If you have trouble swallowing capsules, you can open the capsule and sprinkle the contents onto a small amount of soft food, such as applesauce or pudding.

Swallow the food mixture right away. Do not chew the sprinkle particles, because chewing can damage their coating and change how the medicine is released.

If the contents of a capsule are spilled or lost, discard that capsule and use a new one as directed. Do not try to estimate or replace only part of the dose.

How is the Dose Determined?

The dose of Depakote Sprinkles is individualized. Your healthcare provider will choose your dose based on factors such as your age, body weight, type of seizure, response to treatment, and other medicines you take.

Your dose may need to be adjusted over time. In some cases, your healthcare provider may also check the amount of valproate in your blood to make sure your dose is within an appropriate range.

Tell your healthcare provider about all prescription medicines, over-the-counter products, vitamins, supplements, and herbal products you use. Some medicines can affect valproate levels or increase the risk of side effects.

Usual Starting Dose for Seizures

For many seizure disorders, the usual starting dose is around 10 to 15 mg per kilogram of body weight per day.

Your healthcare provider may slowly increase the dose until your seizures are better controlled or until you reach the highest dose you can safely tolerate.

The maximum recommended dose is generally 60 mg/kg per day.

If your total daily dose is more than 250 mg, it is usually divided into two or more doses during the day rather than taken all at once.

Why is the Dose Increased Slowly?

Starting with a lower dose and increasing it gradually can help reduce the chance of side effects.

It also gives your healthcare provider time to see how well the medicine controls your seizures.

Do not increase your dose on your own, even if you are still having seizures. Contact your healthcare provider if you feel that the medicine is not working well enough.

Take Depakote Sprinkles Regularly

Take Depakote Sprinkles at about the same times each day.

Regular dosing helps keep a steady amount of medication in your bloodstream. This is especially important for seizure control because missed or delayed doses can increase the risk of breakthrough seizures.

Using a pill organizer, phone alarm, or medication schedule may help you remember your doses.

What If You Miss a Dose?

If you miss a dose, take it when you remember unless it is almost time for your next scheduled dose.

If your next dose is coming up soon, skip the missed dose and return to your regular schedule.

Do not take two doses at the same time to make up for a missed dose.

If you miss several doses or are unsure what to do, contact your healthcare provider or pharmacist.

Do Not Stop Depakote Sprinkles Suddenly

Do not stop taking Depakote Sprinkles without medical advice.

Stopping an anticonvulsant suddenly can cause seizures to become more frequent or severe. In some cases, sudden withdrawal may lead to a medical emergency.

If treatment needs to be stopped, your healthcare provider may gradually reduce your dose while monitoring your symptoms.

Taking Depakote Sprinkles With Food

Taking Depakote Sprinkles with food may help reduce nausea, stomach discomfort, or indigestion.

If you use the sprinkle method, place the contents on only a small amount of soft food so you can easily swallow the entire dose.

Do not prepare the mixture ahead of time. Take it immediately after sprinkling the medication onto the food.

Monitoring During Treatment

Your healthcare provider may recommend blood tests while you are taking Depakote Sprinkles.

These tests may be used to check:

  • Valproate levels in your blood
  • Liver function
  • Platelet counts
  • Other blood cell levels

Regular monitoring helps your healthcare provider make sure the medicine is working safely.

Important Reminder

Take Depakote Sprinkles exactly as prescribed. Do not change your dose, skip doses regularly, or stop treatment suddenly.

If you have difficulty swallowing the medicine, experience side effects, continue having seizures, or are unsure about your dosing schedule, speak with your healthcare provider or pharmacist.

Common Side Effects of Depakote Sprinkles (Divalproex):

  • Blurred vision
  • Changes in appetite or weight
  • Dizziness
  • Drowsiness
  • Hair loss
  • Headache
  • Mood changes or depression
  • Nausea
  • Sleep problems
  • Stomach pain
  • Tremors, shaking
  • Vomiting

Serious Side Effects of Depakote Sprinkles (Divalproex):

  • Back pain
  • Blurred vision
  • Bruising or bleeding
  • Changes in weight or appetite
  • Change in your mental state
  • Cold feeling
  • Confusion
  • Memory problems
  • Mood changes
  • Easy bruising, unusual bleeding (nose, mouth, or gums)
  • Fever, swollen glands, mouth sores
  • Purple or red pinpoint spots under your skin
  • Severe drowsiness
  • Tiredness
  • Vomiting

Depakote Sprinkles (Divalproex) is available in the following forms and strength:

Depakote Sprinkles: Delayed Release Capsule

  • 125 mg

Depakote Sprinkle Capsules can cause serious side effects in some people. Before starting treatment, tell your healthcare provider about your medical history and all prescription medicines, over-the-counter products, vitamins, and supplements you take.

Pregnancy

Depakote Sprinkle Capsules contain valproate, which can cause serious harm to an unborn baby, including major birth defects and problems with development and learning.

If you are pregnant, planning to become pregnant, or could become pregnant, talk with your healthcare provider about the risks and available treatment options. Do not suddenly stop taking Depakote Sprinkles, especially if you use them to control seizures.

Liver Problems

Depakote Sprinkles can cause serious liver damage, especially during the first several months of treatment. The risk is higher in children younger than 2 years and in people with certain liver, metabolic, or mitochondrial conditions.

Your healthcare provider may check your liver function before treatment and regularly afterward.

Contact your healthcare provider if you develop unusual tiredness, weakness, loss of appetite, repeated vomiting, swelling of the face, or yellowing of the skin or eyes.

Pancreatitis

Rarely, Depakote Sprinkles can cause pancreatitis, which is inflammation of the pancreas and can become life-threatening.

Seek medical attention right away if you develop severe or ongoing stomach pain, especially if it is accompanied by nausea, vomiting, or loss of appetite.

Mood Changes and Suicidal Thoughts

Antiepileptic medicines such as Depakote Sprinkles may increase the risk of suicidal thoughts or behavior in a small number of people.

Pay attention to new or worsening depression, anxiety, irritability, unusual behavior, or thoughts of harming yourself. Contact your healthcare provider promptly if these changes occur.

Medication Interactions

Depakote Sprinkles can interact with other medicines. These interactions may change the amount of valproate in your body or increase the chance of side effects.

Tell your healthcare provider about everything you take, especially other seizure medicines, certain antidepressants, blood thinners, and medicines that affect the liver or nervous system.

Bleeding and Low Platelet Levels

Depakote Sprinkles can lower the number of platelets in your blood. Platelets help your blood clot normally.

A low platelet count may make you bruise or bleed more easily. Tell your healthcare provider if you notice unexplained bruising, frequent nosebleeds, bleeding gums, or bleeding that takes longer than usual to stop. Your healthcare provider may order blood tests during treatment.

High Ammonia Levels

Depakote Sprinkles can sometimes cause too much ammonia to build up in the blood. This is called hyperammonemia and may affect normal brain function.

Contact your healthcare provider right away if you develop unusual weakness, repeated vomiting, extreme tiredness, confusion, changes in alertness, or difficulty thinking clearly.

Serious Allergic Reactions

Serious allergic reactions can occur with Depakote Sprinkles.

Seek emergency medical attention if you develop hives, difficulty breathing, or swelling of your face, lips, tongue, or throat.

Regular Monitoring

Your healthcare provider may recommend blood tests before and during treatment to check your liver function, platelet count, and other important health measures.

Keep your medical appointments and report any new or unusual symptoms promptly. Do not change your dose or stop taking Depakote Sprinkle Capsules without speaking with your healthcare provider.

Can Depakote Sprinkle Capsules Be Used During Pregnancy?

Depakote Sprinkle Capsules can cause serious harm to an unborn baby, including birth defects and developmental problems. If you are pregnant, planning to become pregnant, or could become pregnant, talk to your healthcare provider about the risks and available treatment options. Do not stop taking Depakote Sprinkles suddenly without medical advice, especially if you use them to control seizures.

How Long Does It Take for Depakote Sprinkle Capsules to Start Working?

How quickly Depakote Sprinkles begin to work can vary from person to person. It depends on the condition being treated, the dose, and how your body responds to the medication. For seizure control, it may take time to find the dose that works best for you. Take the medication regularly as prescribed, even if you do not notice an immediate effect.

Can Depakote Sprinkle Capsules Be Given to Children?

Yes. Depakote Sprinkle Capsules may be prescribed to children for certain seizure disorders. The dose is usually based on the child’s age, body weight, medical condition, and response to treatment. A healthcare provider may adjust the dose gradually and may order blood tests during treatment. Children taking valproate medicines may need closer monitoring because some serious side effects, including liver problems, can occur more often in younger children.

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Additional Information Book
Generic name:

Divalproex

Formulation:

Delayed Release Capsule

Strength(s):

125mg

Quantities Available:

100

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Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.

Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.

How to Order

How much Depakote Sprinkles can I order at once from a Canadian pharmacy?

When ordering Depakote Sprinkles (divalproex) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.

Here’s what you need to know:

Dosage and Quantity: Depakote Sprinkles are commonly prescribed in dosages such as 125 mg, taken once or multiple times daily. For example, if your prescribed dosage is 500 mg per day (which would be four 125 mg capsules per day), for a 90-day supply, you would order 360 capsules (90 days x 4 capsules per day).

Do you sell divalproex?

No, we do not sell divalproex separately. However, you can still enjoy low prices on Depakote Sprinkles, which contains divalproex as an active ingredient. You will need a valid prescription from your healthcare provider to purchase Depakote Sprinkles. We require this prescription to dispense the medication, and you can submit it by mail, fax, or upload through your online account.

Do you offer shipping of Depakote Sprinkles (divalproex) to the United States?

Yes, we ship Depakote Sprinkles (divalproex) to both the United States and Puerto Rico.

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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Depakote Sprinkles (Divalproex). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Depakote Sprinkles (Divalproex).