ORGOVYX may cause changes in the heart’s electrical activity, leading to a condition known as QT interval prolongation. This can result in irregular heartbeats. Individuals with heart conditions, such as congenital long QT syndrome or heart failure, should be closely monitored during treatment. Regular electrocardiograms (ECGs) and electrolyte checks are recommended.
Some patients have experienced severe allergic reactions, including angioedema, characterized by swelling of the face, lips, tongue, or throat, leading to difficulty breathing or swallowing. If such symptoms occur, discontinue ORGOVYX immediately and seek emergency medical attention.
Based on animal studies and its mechanism of action, ORGOVYX can harm an unborn baby and may cause pregnancy loss if administered to a pregnant female. Males with female partners who can become pregnant should use effective contraception during treatment and for two weeks after the last dose.
ORGOVYX can suppress the pituitary-gonadal system, potentially affecting diagnostic tests related to pituitary and gonadal functions. It’s important to monitor prostate-specific antigen (PSA) levels periodically during treatment.
ORGOVYX can interact with various medications, potentially altering its effectiveness or increasing side effects. Inform your healthcare provider about all medications, supplements, and herbal products you are taking. Notably, certain drugs can increase the risk of side effects or reduce the effectiveness of ORGOVYX.
While there are no known direct interactions between ORGOVYX and alcohol, consuming alcohol during treatment may exacerbate certain side effects, such as diarrhea, hot flashes, and fatigue. Excessive alcohol consumption can lead to liver damage, and since ORGOVYX may also affect liver function, it’s advisable to limit alcohol intake during treatment.
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