Indications
Efudex cream is a topical medication that contains the active ingredient fluorouracil, which is an antineoplastic antimetabolite. It is used to treat various skin conditions, including actinic keratoses, basal cell carcinoma, and other types of pre-cancerous and cancerous skin growths. The cream is applied directly to the affected area, and treatment can last for several weeks. It works by blocking the growth of abnormal cells that cause these skin conditions.
Efudex cream is used to treat various skin conditions, including actinic keratoses, basal cell carcinoma, and other types of pre-cancerous and cancerous skin growths. Efudex cream works by blocking the growth of abnormal cells that cause these skin conditions.
Uses and Dosage
Efudex cream is applied directly to the affected area, and treatment can last for several weeks. The cream is applied as a thin layer to the affected area(s) of the skin twice a day. To apply Efudex cream, start by cleaning the affected area and drying it well. Wait for 10 minutes, then apply a small amount of the cream, using just enough to cover the area with a thin film. Be sure to wash your hands immediately after applying the cream, even if you have used gloves.
Note that the treated area may become unsightly during treatment and for several weeks after treatment, and do not cover it with tight dressings or plastic bandages unless advised by your doctor. In addition, avoid applying the cream in or around the eyes or eyelids, as well as inside the nose or mouth. If you accidentally get the medication in these areas, rinse them thoroughly with plenty of water. If you have any questions or concerns, speak to your healthcare provider.
Side Effect
Common Side Effects of Efudex Cream (Fluorouracil):
- Skin redness
- Dry and scaly skin
- Crusting of the skin
- Stinging or burning feeling of the skin
- Skin itchiness
- Swelling of the skin
- Peeling of the skin
Serious Side Effects of Efudex Cream (Fluorouracil):
- Scarring
- Darkening of skin color
- Skin tenderness
- Open sores on skin
- Rash
Form and Strength
Efudex Cream (Fluorouracil) is available in the following forms and strength:
Efudex Cream: Cream
- 5%
Fluorouracil: Cream
- 5%
Caution
- Do not apply Efudex Cream in or around the eyes, eyelids, nose, or mouth. If the medication gets into these areas accidentally, rinse them thoroughly with water.
- Efudex Cream makes the skin more sensitive to sunlight so avoid exposure to the sun during treatment.
- The treated area may become unsightly during treatment and for several weeks after treatment, and do not cover it with tight dressings or plastic bandages unless advised by your doctor.
- Efudex Cream may interact with other medications, foods, or supplements. Therefore, inform your healthcare provider about all the medications and supplements you are taking before starting Efudex Cream.
- Efudex may cause side effects such as redness, swelling, crusting of the skin, and skin peeling or flaking. If you experience any severe or persistent side effects, you should notify your healthcare provider immediately.
- Use caution when applying the medication near the hairline or on the scalp, as hair loss may occur.
- Do not use Efudex Cream on open wounds or broken skin.
- If you are pregnant or breastfeeding, talk to your healthcare provider before using Efudex Cream, as the medication may be harmful to a developing fetus or infant.
- If you have a history of allergies or allergic reactions to medications, foods, or other substances, let your healthcare provider know before starting treatment with Efudex Cream.
- In rare cases, Efudex Cream may cause a severe allergic reaction. Seek immediate medical attention if you experience symptoms such as difficulty breathing, hives, or swelling of the face, lips, tongue, or throat.
- Inform your healthcare provider if you have a history of immune system problems or if you are taking medications that suppress the immune system, as this may increase your risk of developing skin infections while using Efudex Cream.
Frequently Asked Questions (FAQ)
Is Efudex cream available without a prescription?
No, Efudex cream is a prescription medication and should only be used under the guidance and supervision of a qualified healthcare professional.
How long does treatment with Efudex cream last?
The length of treatment with Efudex cream can vary depending on the specific skin condition being treated and the individual patient's needs. Treatment can range from a few days to several weeks.
Can Efudex cream be used during pregnancy or while breastfeeding?
The safety of using Efudex cream during pregnancy or while breastfeeding has not been fully established. It is important to consult with a healthcare professional before using Efudex cream if you are pregnant or breastfeeding.
How should Efudex cream be stored?
Efudex cream should be stored at room temperature, away from heat and moisture. It should be kept out of the reach of children and pets.
Can Efudex cream be used in conjunction with other medications?
Inform your healthcare professional of any other medications you are taking before using Efudex cream, as certain medications may interact with Efudex cream or increase the risk of side effects.
Resources
- https://www.goodrx.com/fluorouracil/what-is
- https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=35de1c1c-bef5-46c5-b6f8-ea032147411c
- https://www.webmd.com/drugs/2/drug-3723/efudex-topical/details
- https://reference.medscape.com/drug/efudex-carac-fluorouracil-topical-343545
- https://chemocare.com/chemotherapy/drug-info/efudex.aspx
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