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Zofran ODT (Ondansetron) Shopper Approved

Prescription Prescription Required FormationFormulation: Orally disintegrating Tablet

Zofran ODT

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Prescription Prescription Required FormationFormulation: Orally disintegrating Tablet

Ondansetron

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Zofran ODT contains the active ingredient ondansetron. It is a prescription medication used to help prevent and control nausea and vomiting.

Nausea and Vomiting From Chemotherapy

Zofran ODT may be used to help prevent nausea and vomiting caused by certain cancer chemotherapy treatments.

It works best when taken according to the schedule provided by your healthcare provider, often before treatment begins.

Nausea and Vomiting From Radiation Therapy

Zofran ODT may also be used to help prevent nausea and vomiting caused by radiation therapy.

The timing of each dose depends on the type and schedule of radiation treatment.

Nausea and Vomiting After Surgery

Zofran ODT may be used to help prevent or treat nausea and vomiting related to surgery and anesthesia.

How Zofran ODT Works

Zofran ODT belongs to a group of medications called 5-HT3 receptor antagonists.

It works by blocking the effects of serotonin, a natural chemical that can trigger the vomiting reflex.

By blocking these signals in the brain and digestive system, Zofran ODT helps reduce nausea and vomiting.

What Does ODT Mean?

ODT stands for orally disintegrating tablet.

The tablet is designed to dissolve quickly on your tongue, so you do not need to swallow it whole with water.

Important Note

Zofran ODT helps prevent and control nausea and vomiting, but it does not treat the underlying cause.

Take it exactly as prescribed and follow the timing instructions provided by your healthcare provider.

Zofran ODT is an orally disintegrating tablet that dissolves on your tongue.

You do not need water to take it.

Place the tablet on your tongue and allow it to dissolve completely before swallowing.

Before Chemotherapy

For adults receiving moderately nausea-causing chemotherapy, the usual dose is:

8 mg taken 30 minutes before chemotherapy.

A second 8 mg dose is usually taken 8 hours after the first dose.

After that, 8 mg is generally taken every 12 hours for 1 to 2 days after chemotherapy is completed.

Different chemotherapy treatments may require different doses. For highly nausea-causing chemotherapy, a different single-dose regimen may be used.

Before Radiation Therapy

The dose and timing depend on the type of radiation therapy you receive.

For some radiation treatments, the usual adult dose is 8 mg taken 1 to 2 hours before treatment.

Additional doses may be needed later in the day or for several days, depending on your radiation schedule.

Before Surgery

Zofran ODT may also be prescribed to prevent nausea and vomiting related to surgery.

For adults, the usual oral dose is 16 mg taken 1 hour before anesthesia begins.

Dosing in Children

Children may receive a different dose based on their age and treatment plan.

For chemotherapy-related nausea and vomiting, pediatric dosing differs between younger children and adolescents.

Always give the exact dose prescribed by the child’s healthcare provider.

Take Zofran ODT Exactly as Prescribed

Do not take more Zofran ODT or take it more often than prescribed.

The correct schedule depends on whether you are receiving chemotherapy, radiation therapy, surgery, or another treatment.

Follow the instructions on your prescription carefully.

What to Do If You Miss a Dose

If you are taking Zofran ODT on a regular schedule and miss a dose, take it when you remember unless it is almost time for your next dose.

If your next dose is approaching, skip the missed dose and continue with your regular schedule.

Do not take two doses at the same time unless your healthcare provider specifically tells you to.

Common Side Effects of Zofran ODT (Ondansetron):

  • Chills
  • Constipation
  • Diarrhea
  • Drowsiness
  • Headache
  • Tired feeling
  • Tiredness
  • Weakness

Serious Side Effects of Zofran ODT (Ondansetron):

  • Agitation
  • Bloating
  • Blurred vision
  • Diarrhea
  • Fainting
  • Fast heart rate
  • Pounding heartbeats
  • Fever
  • Hallucinations
  • Headache with chest pain and severe dizziness
  • Loss of coordination
  • Nausea
  • Overactive reflexes
  • Severe constipation
  • Stomach pain
  • Temporary vision loss
  • Vomiting
  • Yellowing of the skin or eyes (jaundice)

Zofran ODT (Ondansetron) is available in the following forms and strength:

Zofran ODT: Orally Disintegrating Tablet

  • 4 mg
  • 8 mg

Ondansetron: Orally Disintegrating Tablet

  • 4 mg
  • 8 mg

Heart Rhythm Problems

Zofran ODT can affect the electrical activity of the heart and may cause QT prolongation.

In rare cases, this can lead to a serious abnormal heart rhythm called torsades de pointes.

The risk may be higher if you:

  • Have congenital long QT syndrome
  • Have heart failure
  • Have a slow or abnormal heartbeat
  • Have low potassium or magnesium levels
  • Take other medications that prolong the QT interval

Seek medical attention if you develop a fast or irregular heartbeat, severe dizziness, or fainting.

Serotonin Syndrome

Zofran ODT can rarely contribute to serotonin syndrome, especially when it is taken with other medications that increase serotonin.

These may include some antidepressants, tramadol, lithium, fentanyl, and certain other medicines.

Seek medical attention if you develop symptoms such as:

  • Agitation or confusion
  • Fast heartbeat
  • Sweating
  • Fever
  • Muscle stiffness
  • Tremors
  • Poor coordination

Serotonin syndrome can be serious and requires prompt treatment.

Allergic Reactions

Serious allergic reactions can occur.

Seek emergency medical attention if you develop:

  • Hives
  • Severe rash
  • Swelling of the face, lips, tongue, or throat
  • Difficulty breathing or swallowing

People who have had an allergic reaction to another 5-HT3 receptor antagonist may also be at increased risk.

Liver Problems

Ondansetron is processed mainly by the liver.

If you have severe liver impairment, your dose may need to be limited.

Tell your healthcare provider if you have liver disease before starting Zofran ODT.

Kidney Problems

Kidney impairment usually does not require a dose adjustment of ondansetron.

However, tell your healthcare provider if you have significant kidney disease so your overall treatment can be monitored appropriately.

Phenylketonuria (PKU)

Many ondansetron orally disintegrating tablets contain aspartame, which provides phenylalanine.

If you have phenylketonuria (PKU), check the product label or ask your pharmacist how much phenylalanine your specific tablet contains.

Constipation and Bowel Problems

Zofran ODT can cause constipation.

It may also hide signs of a slowing or blockage of the intestines, especially after abdominal surgery or during chemotherapy.

Contact your healthcare provider if you develop:

  • Severe abdominal swelling
  • Persistent constipation
  • Severe stomach pain
  • Vomiting
  • Little or no bowel movement

These symptoms may require medical evaluation.

Drug Interactions

Tell your healthcare provider about all prescription medications, over-the-counter products, vitamins, supplements, and herbal products you use.

Zofran ODT can interact with several medications.

Do not use ondansetron with apomorphine, because the combination can cause severe low blood pressure and loss of consciousness.

Extra caution is also needed with serotonergic medicines and drugs that can prolong the QT interval.

Pregnancy

Tell your healthcare provider if you are pregnant or planning to become pregnant.

Available human pregnancy data have not established a clear drug-related risk of major birth defects or miscarriage.

Your healthcare provider will consider your symptoms and overall health before recommending treatment.

Breastfeeding

Tell your healthcare provider if you are breastfeeding.

There is limited information about ondansetron in human breast milk.

Your healthcare provider will consider the benefits of breastfeeding, your need for treatment, and any potential risk to the nursing infant.

Dizziness and Vision Changes

Ondansetron may occasionally cause dizziness or vision changes.

Avoid driving or operating machinery if you feel dizzy or your vision is affected.

Rare cases of temporary vision loss have been reported, mainly with intravenous ondansetron rather than oral tablets.

Older Adults

Older adults may be more likely to have heart rhythm problems or take other medications that affect the QT interval.

Your healthcare provider may recommend closer monitoring if you have heart disease, electrolyte problems, or take several medications.

When to Seek Medical Attention

Seek prompt medical attention if you develop fainting, an irregular heartbeat, severe allergic symptoms, severe confusion, muscle rigidity, severe abdominal swelling, or other unusual or worsening symptoms.

Is Zofran ODT addictive?

No. Zofran ODT is not considered addictive and is not known to cause physical dependence. Take it only as prescribed for nausea and vomiting.

How long does it take for Zofran ODT to work?

Zofran ODT usually starts working within about 30 minutes to 1 hour after a dose. How long the effect lasts can vary depending on the dose, the cause of nausea, and your individual response.

Can children take Zofran ODT?

Yes. Ondansetron ODT can be used in certain children. For chemotherapy-related nausea and vomiting, current oral dosing information includes children 4 years of age and older, with the dose based mainly on age and treatment plan. Children should only take ondansetron when it has been prescribed by a healthcare provider.

Can Zofran ODT be used for motion sickness?

Zofran ODT is not routinely used for motion sickness. Ondansetron is designed to block serotonin signals involved in certain types of nausea and vomiting, such as those caused by chemotherapy, radiation therapy, or surgery. Motion sickness works through different pathways, so other medications are usually more appropriate.

Does Zofran ODT cause drowsiness?

Drowsiness is not one of the most common side effects of Zofran ODT. Some people may experience dizziness, headache, or tiredness. Avoid driving or operating machinery if you feel dizzy or if the medication affects your ability to concentrate.

REVIEWS

Additional Information Book
Generic name:

Ondansetron, Ondansetron ODT

Formulation:

Orally Disintegrating Tablet, Orally disintegrating Tablet

Strength(s):

4mg, 8mg

Quantities Available:

10, 30, 60

Why customers love Online Pharmacies Canada

Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.

Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.

How to Order

How much Zofran ODT can I order at once from a Canadian pharmacy?

When ordering Zofran ODT (ondansetron ODT) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of conditions without frequent refills.

Here’s what you need to know:

Dosage and Quantity: Zofran ODT is commonly prescribed in dosages of 4 mg or 8 mg, taken as needed. For example, if prescribed 8 mg tablets and taking one tablet twice daily, a 90-day supply would mean ordering 180 tablets (90 days x 2 tablets per day).

Do you sell ondansetron ODT?

Yes, we sell ondansetron ODT on our website. You can enjoy low prices when you order through us. To purchase ondansetron ODT, you will need a valid prescription from your healthcare provider. We require this prescription to dispense the medication safely and appropriately. You have the option to submit your prescription by mailing it to us, faxing it, or uploading it through your online account.

Do you offer shipping of Zofran ODT (ondansetron ODT) to the United States?

Yes, we ship Zofran ODT (ondansetron ODT) to both the United States and Puerto Rico.

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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Zofran ODT (Ondansetron). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Zofran ODT (Ondansetron).