Table of contents:
Indications
Afinitor is a prescription medication indicated to treat certain types of kidney cancer, breast cancer, or brain tumor. It contains an active ingredient called Everolimus. Afinitor belongs to the class of drugs known as mTOR inhibitors, which are a type of selective immunosuppressant medication used to treat certain types of cancer and tumors. Afinitor interferes with the growth of cancer cells and slows their spread in the body.
Afinitor is indicated for the treatment of hormone receptor-positive, HER2/neu-negative advanced breast cancer in combination with exemestane, in postmenopausal women who have previously received endocrine therapy. It can be used to treat benign brain or kidney tumors, as well as certain types of seizures in individuals diagnosed with tuberous sclerosis complex, a genetic disorder. It is also used to treat certain types of advanced or progressive tumors of the stomach, intestines, or pancreas.
Uses and Dosage
To use Afinitor (Everolimus) tablets, you should follow the prescribed dosage and administration instructions provided by your healthcare provider. Typically, Afinitor tablets are taken by mouth once a day with a full glass of water. The tablets should be swallowed whole and should not be crushed, chewed, or broken. Talk to your healthcare provider about the appropriate dosage and administration of Afinitor based on your individual medical condition and needs.
The recommended dosage of Afinitor (Everolimus) may vary depending on the specific medical condition being treated.
- For Hormone Receptor-Positive, HER2-Negative Breast Cancer: The recommended dosage of AFINITOR is 10 mg orally once daily until disease progression or unacceptable toxicity.
- For Neuroendocrine Tumors (NET): The recommended dosage of Afinitor is 10 mg orally once daily until disease progression or unacceptable toxicity.
- For Renal Cell Carcinoma (RCC): The recommended dosage of Afinitor is 10 mg orally once daily until disease progression or unacceptable toxicity.
- For Tuberous Sclerosis Complex (TSC)-Associated Renal Angiomyolipoma: The recommended dosage of Afinitor is 10 mg orally once daily until disease progression or unacceptable toxicity.
Talk to your healthcare provider about the appropriate dosage and administration of Afinitor based on your individual medical condition and needs.
Side effect
Common Side Effects of Afinitor (Everolimus):
- Cough
- Feeling weak or tired
- Fever
- Headache
- Infections
- Loss of appetite
- Missed menstrual periods
- Mouth sores
- Nausea
- Rash
- Swelling anywhere in your body
Serious Side Effects of Afinitor (Everolimus):
- Any wound that will not heal
- Blisters or ulcers in your mouth
- Chest pain
- Easy bruising
- Feeling light-headed
- Feeling short of breath
- Fever
- Flu-like symptoms
- Little or no urination
- New or worsening cough
- Pale skin, cold hands and feet
- Red or swollen gums
- Skin sores
- Swelling in your feet or ankles
- Trouble swallowing
- Unusual bleeding
- Wheezing
- Yellowing of the skin or eyes
Form and strength
Afinitor (Everolimus) is available in the following forms and strength:
Afinitor: Tablet
- 2.5 mg
- 5 mg
- 10 mg
Caution
- Everolimus may cause fertility problems, including a risk to unborn babies and an increased risk of birth defects.
- Afinitor may cause high blood pressure (hypertension), which should be monitored closely by healthcare professionals.
- Everolimus may cause kidney problems, including kidney failure or proteinuria.
- Afinitor may cause lung or breathing problems, including interstitial lung disease or pneumonitis.
- Everolimus may cause mouth sores, which can become severe and lead to infections.
- Afinitor may increase the risk of certain types of cancers, including skin cancer and lymphoma.
- Afinitor may increase the risk of severe infections, including bacterial, viral, and fungal infections.
- Use caution with Afinitor in patients with diabetes, as it may increase blood sugar levels.
- Afinitor may cause dizziness or fatigue, which may affect a person's ability to operate machinery or drive.
- Afinitor may cause changes in vision, including blurry vision or difficulty seeing at night.
- Use caution with Afinitor in patients with liver problems, as it may worsen liver function.
Frequently Asked Questions (FAQ)
What is the typical dosage of Afinitor?
The dosage of Afinitor may vary depending on the condition being treated but the typical dosage of Afinitor is 10 mg once daily.
What should I do if I miss a dose of Afinitor?
If you miss a dose of Afinitor, you should take it as soon as possible. If it is close to the time for your next dose, skip the missed dose and take your next dose at the usual time. Do not take a double dose to make up for the missed one.
Can Afinitor be taken with other medications?
Inform your doctor of all the medications, vitamins, and supplements you are taking before starting treatment with Afinitor. Some medications may interact with Afinitor and affect how it works or increase the risk of side effects.
How long does it take for Afinitor to work?
The time it takes for Afinitor to work may vary depending on the condition being treated and other factors. Continue taking Afinitor for as long as directed, even if you do not notice any immediate improvement.
Resources
- https://www.medicalnewstoday.com/articles/326055
- https://www.us.afinitor.com/advanced-renal-cell-carcinoma/about-treatment/how-to-take/
- https://www.drugs.com/afinitor.html
- https://www.breastcancer.org/treatment/targeted-therapy/afinitor
- https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2150f73a-179b-4afc-b8ce-67c85cc72f04
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/022334s016lbl.pdf
It's important to purchase Afinitor from verified Canadian pharmacy.
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